SMAD3 (Homo sapiens)
SMAD

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF03165 (MH1) IPR003619 ENSG00000166949 T324629_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
The SMAD family of proteins are a group of intracellular signal transducer proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. The SMAD3 protein functions in the transforming growth factor-beta signaling pathway, and transmits signals from the cell surface to the nucleus, regulating gene activity and cell proliferation. This protein forms a complex with other SMAD proteins and binds DNA, functioning both as a transcription factor and tumor suppressor. Mutations in this gene are associated with aneurysms-osteoarthritis syndrome and Loeys-Dietz Syndrome 3. [provided by RefSeq, May 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
SMAD3
M03482_2.00		 Homo sapiens
YGTCTAGACA
TGTCTAGACR		 SELEX
Jolma et al.(2013)
SMAD3_1		 (Direct) (Direct)
SMAD3
M09380_2.00		 Homo sapiens
NBCTSHCWSCWB
VWGSWGDSAGVN		 Misc
Kulakovskiy et al.(2013)
SMAD3_HUMAN.H11MO.0.B		 (Direct) (Direct)
SMAD3
M11283_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD3_Q6_01		 (Direct) (Direct)
SMAD3
M11284_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD3_Q6_02		 (Direct) (Direct)
SMAD3
M11285_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD3_Q6		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Smad3
M00192_2.00 		Mus musculus
NNNNNMGMCN
NGKCKNNNNN		 PBM
Badis et al.(2009)
Smad3_3805 		0.984 0.984
Smad3
M09384_2.00 		Mus musculus
NBCTSHCWSCWB
VWGSWGDSAGVN		 Misc
Kulakovskiy et al.(2013)
SMAD3_MOUSE.H11MO.0.B 		1.000 1.000
Smad3
M09637_2.00 		Mus musculus
BYAGMCWN
NWGKCTRV		 Misc
Heinz et al.(2010)
NPC-Smad3_GSE36673 		1.000 1.000
SMAD1
M11286_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD1_01 		0.781 0.781
SMAD9
M11274_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD8_01 		0.723 0.723
Smad9
M11290_2.00 		Rattus norvegicus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD8_02 		0.723 0.723
SMAD1
M11287_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD1_Q6 		0.781 0.781
Smad9
M11289_2.00 		Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD8_03 		0.723 0.723
Mad
M06446_2.00 		Drosophila melanogaster
GYGHCGBCVS
SBGVCGDCRC		 B1H
Zhu et al.(2011)
Mad_FlyReg_FBgn0011648 		0.703 0.703
Mad
M08427_2.00 		Drosophila melanogaster
SNGRCGMSRVSRBNS
SNVYSBYSKCGYCNS		 ChIP-chip
Mathelier et al.(2014)
MA0535.1 		0.703 0.703
Mad
M09692_2.00 		Drosophila melanogaster
KCBGSHGKCGCSNC
GNSGCGMCDSCVGM		 Misc
Kulakovskiy et al.(2009)
Mad 		0.703 0.703
Mad
M11293_2.00 		Drosophila melanogaster Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
I$MAD_Q6 		0.703 0.703
Smad5
M11288_2.00 		Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD5_01 		0.703 0.703
Smad5
M11292_2.00 		Rattus norvegicus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD5_03 		0.703 0.703
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000332973 SMAD 31 131
ENSP00000401133 SMAD 5 87
ENSP00000437757 SMAD 1 26
ENSP00000453082 SMAD 1 26
ENSP00000453684 SMAD 1 26
ENSP00000455095 SMAD 1 26
ENSP00000458060 SMAD 1 26

Links

Other SMAD family TFs
Other Homo sapiens TFs

393 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
SMAD3 Callithrix jacchus ENSCJAG00000002088 I 1.000
ENSNLEG00000012983 Nomascus leucogenys ENSNLEG00000012983 I 1.000
ENSOARG00000018276 Ovis aries ENSOARG00000018276 I 1.000
ENSTBEG00000003884 Tupaia belangeri ENSTBEG00000003884 I 1.000
ENSSTOG00000010286 Ictidomys tridecemlineatus ENSSTOG00000010286 I 1.000
Myotis_brandtii_Smad3_10022298 Myotis brandtii Myotis_brandtii_Smad3_10022298 I 1.000
ENSAMEG00000003318 Ailuropoda melanoleuca ENSAMEG00000003318 I 1.000
SMAD3 Myotis lucifugus ENSMLUG00000002185 I 1.000
ENSMPUG00000000304 Mustela putorius furo ENSMPUG00000000304 I 1.000
SMAD3 Microcebus murinus ENSMICG00000006119 I 1.000
SMAD3 Canis familiaris ENSCAFG00000017388 I 1.000
Smad3 Mus musculus ENSMUSG00000032402 D 1.000
SMAD3 Bos taurus ENSBTAG00000012599 I 1.000
SMAD3 Otolemur garnettii ENSOGAG00000014217 I 1.000
SMAD3 Pteropus vampyrus ENSPVAG00000002626 I 1.000
ENSPPYG00000006583 Pongo abelii ENSPPYG00000006583 I 1.000
SMAD3 Felis catus ENSFCAG00000027081 I 1.000
SMAD3 Pan troglodytes ENSPTRG00000007199 I 1.000
Smad3 Rattus norvegicus ENSRNOG00000008620 I 1.000
SMAD3 Ochotona princeps ENSOPRG00000014996 I 1.000
SMAD3 Sus scrofa ENSSSCG00000004952 I 1.000
SMAD3 Dasypus novemcinctus ENSDNOG00000044090 I 1.000
ENSP00000332973-D1 Bos grunniens ENSP00000332973-D1 I 1.000
SMAD3 Procavia capensis ENSPCAG00000008103 I 1.000
SMAD3 Choloepus hoffmanni ENSCHOG00000001562 I 0.990
ENSCSAG00000013275 Chlorocebus sabaeus ENSCSAG00000013275 I 0.990
SMAD3 Macaca mulatta ENSMMUG00000015455 I 0.990
ENSPANG00000016627 Papio anubis ENSPANG00000016627 I 0.990
SMAD3 Cavia porcellus ENSCPOG00000021314 I 0.984
ENSFALG00000012861 Ficedula albicollis ENSFALG00000012861 I 0.980
SMAD3 Echinops telfairi ENSETEG00000003356 I 0.980
SMAD3 Monodelphis domestica ENSMODG00000009609 I 0.980
Gfo_R005908 Geospiza fortis Gfo_R005908 I 0.980
Brh_R001114 Buceros rhinoceros Brh_R001114 I 0.974
ENSGMOG00000001314 Gadus morhua ENSGMOG00000001314 I 0.974
Aan_R005610 Calypte anna Aan_R005610 I 0.970
ENSGALG00000007870 Gallus gallus ENSGALG00000007870 I 0.970
Afo_R015053 Aptenodytes forsteri Afo_R015053 I 0.970
SMAD3 Equus caballus ENSECAG00000020259 I 0.969
Tal_R001210 Tyto alba Tal_R001210 I 0.968
ENSAPLG00000007006 Anas platyrhynchos ENSAPLG00000007006 I 0.968
Brh_R001115 Buceros rhinoceros Brh_R001115 I 0.968
ENSPSIG00000010579 Pelodiscus sinensis ENSPSIG00000010579 I 0.968
ENSMEUG00000016668 Macropus eugenii ENSMEUG00000016668 I 0.962
ENSAMXG00000002880 Astyanax mexicanus ENSAMXG00000002880 I 0.960
smad3a Danio rerio ENSDARG00000036096 I 0.960
Cmyd_10013581 Chelonia mydas Cmyd_10013581 I 0.953
Alligator_sinensis_CCG004626.1 Alligator sinensis Alligator_sinensis_CCG004626.1 I 0.953
Pvit_04529 Pogona vitticeps Pvit_04529 I 0.953
smad3 Xenopus tropicalis XB-GENE-481992 I 0.953
SMAD3 Anolis carolinensis ENSACAG00000009914 I 0.953
SMAD3 Taeniopygia guttata ENSTGUG00000009470 I 0.953
ENSLOCG00000013897 Lepisosteus oculatus ENSLOCG00000013897 I 0.951
SMAD3 Meleagris gallopavo ENSMGAG00000009879 I 0.949
Tal_R011237 Tyto alba Tal_R011237 I 0.947
ENSAPLG00000011496 Anas platyrhynchos ENSAPLG00000011496 I 0.947
ENSPFOG00000006336 Poecilia formosa ENSPFOG00000006336 I 0.941
smad3a Takifugu rubripes ENSTRUG00000016858 I 0.941
smad3a Tetraodon nigroviridis ENSTNIG00000009546 I 0.941
ENSP00000332973 Macaca fascicularis ENSP00000332973 I 0.941
ENSGMOG00000008364 Gadus morhua ENSGMOG00000008364 I 0.931
ENSXMAG00000002377 Xiphophorus maculatus ENSXMAG00000002377 I 0.931
ENSMGAG00000001351 Meleagris gallopavo ENSMGAG00000001351 I 0.931
ENSONIG00000013271 Oreochromis niloticus ENSONIG00000013271 I 0.931
Aan_R002236 Calypte anna Aan_R002236 I 0.931
smad3b Gasterosteus aculeatus ENSGACG00000005092 I 0.931
ENSGALG00000014184 Gallus gallus ENSGALG00000014184 I 0.931
AAB39329 Xenopus laevis AAB39329 I 0.931
Ogr07749 Ophisaurus gracilis Ogr07749 I 0.923
ENSLACG00000010552 Latimeria chalumnae ENSLACG00000010552 I 0.922
smad2.S Xenopus laevis XB-GENE-864923 I 0.921
smad3b Danio rerio ENSDARG00000010207 I 0.921
ENSGACG00000017820 Gasterosteus aculeatus ENSGACG00000017820 I 0.921
ENSONIG00000015464 Oreochromis niloticus ENSONIG00000015464 I 0.921
SMAD2 Sorex araneus ENSSARG00000003487 I 0.921
smad3a Oryzias latipes ENSORLG00000002207 I 0.921
ENSORLG00000011834 Oryzias latipes ENSORLG00000011834 I 0.921
Gfo_R012055 Geospiza fortis Gfo_R012055 I 0.921
ENSSTOG00000003788 Ictidomys tridecemlineatus ENSSTOG00000003788 I 0.921
smad3.L Xenopus laevis XB-GENE-864816 I 0.921
ENSBTAP00000003668-D4 Bos grunniens ENSBTAP00000003668-D4 I 0.921
smad3b Oryzias latipes ENSORLG00000006803 I 0.911
ENSONIG00000004109 Oreochromis niloticus ENSONIG00000004109 I 0.911
ENSAPLG00000004964 Anas platyrhynchos ENSAPLG00000004964 I 0.906
ENSPFOG00000002285 Poecilia formosa ENSPFOG00000002285 I 0.901
SMAR008230 Strigamia maritima SMAR008230 I 0.901
ENSPFOG00000004885 Poecilia formosa ENSPFOG00000004885 I 0.901
smad3b Tetraodon nigroviridis ENSTNIG00000008432 I 0.901
ENSXMAG00000003553 Xiphophorus maculatus ENSXMAG00000003553 I 0.891
ENSTNIG00000004827 Tetraodon nigroviridis ENSTNIG00000004827 I 0.891
ENSPFOG00000008802 Poecilia formosa ENSPFOG00000008802 I 0.891
ENSXMAG00000004505 Xiphophorus maculatus ENSXMAG00000004505 I 0.891
smad3b Takifugu rubripes ENSTRUG00000014802 I 0.891
ENSPMAG00000004234 Petromyzon marinus ENSPMAG00000004234 I 0.889
ENSSHAG00000012543 Sarcophilus harrisii ENSSHAG00000012543 I 0.877
Sakowv30032201m.g Saccoglossus kowalevskii Sakowv30032201m.g I 0.875
ENSPMAG00000000489 Petromyzon marinus ENSPMAG00000000489 I 0.871
L798_14024 Zootermopsis nevadensis L798_14024 I 0.871
ISCW001846 Ixodes scapularis ISCW001846 I 0.859
ENSTRUG00000002512 Takifugu rubripes ENSTRUG00000002512 I 0.859
NEMVEDRAFT_v1g168041 Nematostella vectensis NEMVEDRAFT_v1g168041 I 0.859
SPU_017642 Strongylocentrotus purpuratus SPU_017642 I 0.844
ACEP23524 Atta cephalotes ACEP23524 I 0.842
SMAD2 Microcebus murinus ENSMICG00000007882 I 0.837
estExt_fgenesh2_pg.C_1720042 Branchiostoma floridae estExt_fgenesh2_pg.C_1720042 I 0.832
estExt_gwp.C_540260 Branchiostoma floridae estExt_gwp.C_540260 I 0.832
ML011743a Mnemiopsis leidyi ML011743a I 0.830
CapteG167863 Capitella teleta CapteG167863 I 0.828
DAPPUDRAFT_314805 Daphnia pulex DAPPUDRAFT_314805 I 0.828
ENSETEG00000017446 Echinops telfairi ENSETEG00000017446 I 0.828
CGI_10017370 Crassostrea gigas CGI_10017370 I 0.822
TriadG49742 Trichoplax adhaerens TriadG49742 I 0.812
ENSCSAVG00000004749 Ciona savignyi ENSCSAVG00000004749 I 0.797
SMAD9 Dasypus novemcinctus ENSDNOG00000048385 I 0.797
PPAI005080 Phlebotomus papatasi PPAI005080 I 0.795
LotgiG189014 Lottia gigantea LotgiG189014 I 0.792
AAL86774 Xenopus laevis AAL86774 I 0.781
ENSSTOG00000007103 Ictidomys tridecemlineatus ENSSTOG00000007103 I 0.781
SMAD9 Sorex araneus ENSSARG00000011878 I 0.781
SMAD1 Pteropus vampyrus ENSPVAG00000014298 I 0.781
Smad9 Rattus norvegicus ENSRNOG00000000091 D 0.781
SMAD9 Pteropus vampyrus ENSPVAG00000013871 I 0.781
D918_06928 Trichuris suis D918_06928 I 0.781
TTRE_0000645601 Trichuris trichiura TTRE_0000645601 I 0.781
SMAD1 Pan troglodytes ENSPTRG00000016485 I 0.781
XP_002160208.1 Hydra magnipapillata XP_002160208.1 I 0.781
Smad1 Rattus norvegicus ENSRNOG00000018483 I 0.781
ENSSHAG00000006387 Sarcophilus harrisii ENSSHAG00000006387 I 0.781
HHAL005200-PA Halyomorpha halys HHAL005200-PA I 0.781
ENSSHAG00000001186 Sarcophilus harrisii ENSSHAG00000001186 I 0.781
AAL86773 Xenopus laevis AAL86773 I 0.781
LOC103691556 Rattus norvegicus ENSRNOG00000058416 I 0.781
smad9 Xenopus tropicalis XB-GENE-484686 I 0.781
SMAD9 Sus scrofa ENSSSCG00000009357 I 0.781
SMAD9 Tursiops truncatus ENSTTRG00000007903 I 0.781
SMAD9 Pan troglodytes ENSPTRG00000005788 I 0.781
Aan_R003078 Calypte anna Aan_R003078 I 0.781
Aan_R005227 Calypte anna Aan_R005227 I 0.781
ENSP00000382216 Macaca fascicularis ENSP00000382216 I 0.781
TriadG50301 Trichoplax adhaerens TriadG50301 I 0.781
tetur04g09040 Tetranychus urticae tetur04g09040 I 0.781
Gfo_R005758 Geospiza fortis Gfo_R005758 I 0.781
Gfo_R000868 Geospiza fortis Gfo_R000868 I 0.781
Afo_R003117 Aptenodytes forsteri Afo_R003117 I 0.781
Afo_R005797 Aptenodytes forsteri Afo_R005797 I 0.781
Alligator_sinensis_CCG012577.1 Alligator sinensis Alligator_sinensis_CCG012577.1 I 0.781
Cmyd_10015900 Chelonia mydas Cmyd_10015900 I 0.781
Brh_R009512 Buceros rhinoceros Brh_R009512 I 0.781
ENSBTAP00000003668-D1 Bos grunniens ENSBTAP00000003668-D1 I 0.781
Alligator_sinensis_CCG006386.1 Alligator sinensis Alligator_sinensis_CCG006386.1 I 0.781
ENSP00000377652 Macaca fascicularis ENSP00000377652 I 0.781
ENSBTAP00000029021-D3 Bos grunniens ENSBTAP00000029021-D3 I 0.781
PHUM612590 Pediculus humanus PHUM612590 I 0.781
PHUM612490 Pediculus humanus PHUM612490 I 0.781
Brh_R002100 Buceros rhinoceros Brh_R002100 I 0.781
Tal_R004657 Tyto alba Tal_R004657 I 0.781
SMAD1 Tursiops truncatus ENSTTRG00000008086 I 0.781
ENSTSYG00000005021 Tarsius syrichta ENSTSYG00000005021 I 0.781
Sakowv30001252m.g Saccoglossus kowalevskii Sakowv30001252m.g I 0.781
AAK02019 Xenopus laevis AAK02019 I 0.781
SMAD9 Tupaia belangeri ENSTBEG00000011491 I 0.781
SMAD1 Taeniopygia guttata ENSTGUG00000002675 I 0.781
Tal_R004006 Tyto alba Tal_R004006 I 0.781
Pvit_04328 Pogona vitticeps Pvit_04328 I 0.781
Myotis_brandtii_SMAD9_10010468 Myotis brandtii Myotis_brandtii_SMAD9_10010468 I 0.781
Myotis_brandtii_SMAD1_10016918 Myotis brandtii Myotis_brandtii_SMAD1_10016918 I 0.781
NEMVEDRAFT_v1g228395 Nematostella vectensis NEMVEDRAFT_v1g228395 I 0.781
Ogr00592 Ophisaurus gracilis Ogr00592 I 0.781
L798_03803 Zootermopsis nevadensis L798_03803 I 0.781
HelroG186716 Helobdella robusta HelroG186716 I 0.781
Pvit_02496 Pogona vitticeps Pvit_02496 I 0.781
ENSSTOG00000010836 Ictidomys tridecemlineatus ENSSTOG00000010836 I 0.781
SMAD1 Tupaia belangeri ENSTBEG00000016459 I 0.781
SMAD9 Gallus gallus ENSGALG00000017050 I 0.781
SMAD9 Gorilla gorilla ENSGGOG00000001017 I 0.781
ENSGGOG00000022121 Gorilla gorilla ENSGGOG00000022121 I 0.781
ENSLACG00000011178 Latimeria chalumnae ENSLACG00000011178 I 0.781
SMAD1 Gallus gallus ENSGALG00000009977 I 0.781
SMAD1 Homo sapiens ENSG00000170365 D 0.781
ENSFALG00000008280 Ficedula albicollis ENSFALG00000008280 I 0.781
SMAD9 Felis catus ENSFCAG00000003813 I 0.781
SMAD1 Felis catus ENSFCAG00000004136 I 0.781
SMAD9 Homo sapiens ENSG00000120693 D 0.781
ENSLACG00000011249 Latimeria chalumnae ENSLACG00000011249 I 0.781
SMAD9 Loxodonta africana ENSLAFG00000002903 I 0.781
SMAD9 Microcebus murinus ENSMICG00000003343 I 0.781
SMAD9 Myotis lucifugus ENSMLUG00000006399 I 0.781
SMAD1 Myotis lucifugus ENSMLUG00000012261 I 0.781
SMAD9 Macaca mulatta ENSMMUG00000009914 I 0.781
SMAD1 Microcebus murinus ENSMICG00000000562 I 0.781
SMAD9 Meleagris gallopavo ENSMGAG00000015060 I 0.781
SMAD1 Loxodonta africana ENSLAFG00000018345 I 0.781
ENSMEUG00000007556 Macropus eugenii ENSMEUG00000007556 I 0.781
SMAD1 Meleagris gallopavo ENSMGAG00000003725 I 0.781
ENSFALG00000005536 Ficedula albicollis ENSFALG00000005536 I 0.781
SMAD9 Echinops telfairi ENSETEG00000020236 I 0.781
ENSAPLG00000012107 Anas platyrhynchos ENSAPLG00000012107 I 0.781
SMAD1 Bos taurus ENSBTAG00000002835 I 0.781
SMAD9 Bos taurus ENSBTAG00000007589 I 0.781
SMAD9 Canis familiaris ENSCAFG00000006162 I 0.781
ENSAPLG00000009135 Anas platyrhynchos ENSAPLG00000009135 I 0.781
ENSAMEG00000016645 Ailuropoda melanoleuca ENSAMEG00000016645 I 0.781
SMAD1 Anolis carolinensis ENSACAG00000003544 I 0.781
SMAD9 Anolis carolinensis ENSACAG00000004463 I 0.781
ENSAMEG00000014442 Ailuropoda melanoleuca ENSAMEG00000014442 I 0.781
SMAD1 Canis familiaris ENSCAFG00000007659 I 0.781
SMAD1 Choloepus hoffmanni ENSCHOG00000009259 I 0.781
SMAD9 Equus caballus ENSECAG00000012534 I 0.781
SMAD1 Equus caballus ENSECAG00000022649 I 0.781
SMAD1 Erinaceus europaeus ENSEEUG00000008384 I 0.781
SMAD1 Echinops telfairi ENSETEG00000016533 I 0.781
Smad9 Dipodomys ordii ENSDORG00000002526 I 0.781
ENSPSIG00000016396 Pelodiscus sinensis ENSPSIG00000016396 I 0.781
SMAD1 Callithrix jacchus ENSCJAG00000002542 I 0.781
SMAD1 Cavia porcellus ENSCPOG00000009073 I 0.781
ENSCSAG00000017872 Chlorocebus sabaeus ENSCSAG00000017872 I 0.781
SMAD1 Macaca mulatta ENSMMUG00000018384 I 0.781
SMAD1 Dasypus novemcinctus ENSDNOG00000048112 I 0.781
ENSPANG00000014460 Papio anubis ENSPANG00000014460 I 0.781
ENSPMAG00000009833 Petromyzon marinus ENSPMAG00000009833 I 0.781
ENSPSIG00000002483 Pelodiscus sinensis ENSPSIG00000002483 I 0.781
SMAD9 Procavia capensis ENSPCAG00000002604 I 0.781
SMAD9 Ochotona princeps ENSOPRG00000004923 I 0.781
ENSNLEG00000001639 Nomascus leucogenys ENSNLEG00000001639 I 0.781
SMAD9 Monodelphis domestica ENSMODG00000010017 I 0.781
SMAD1 Ochotona princeps ENSOPRG00000012775 I 0.781
ENSMPUG00000006867 Mustela putorius furo ENSMPUG00000006867 I 0.781
ENSMPUG00000001838 Mustela putorius furo ENSMPUG00000001838 I 0.781
SMAD1 Monodelphis domestica ENSMODG00000000500 I 0.781
ENSONIG00000012614 Oreochromis niloticus ENSONIG00000012614 I 0.781
SMAD9 Otolemur garnettii ENSOGAG00000002742 I 0.781
Smad9 Mus musculus ENSMUSG00000027796 D 0.781
ENSPANG00000016688 Papio anubis ENSPANG00000016688 I 0.781
Smad1 Mus musculus ENSMUSG00000031681 I 0.781
SMAD1 Ornithorhynchus anatinus ENSOANG00000006538 I 0.781
ENSNLEG00000005537 Nomascus leucogenys ENSNLEG00000005537 I 0.781
SMAD1 Otolemur garnettii ENSOGAG00000000150 I 0.781
SMAD9 Oryctolagus cuniculus ENSOCUG00000007453 I 0.781
ENSOARG00000009089 Ovis aries ENSOARG00000009089 I 0.781
SMAD9 Ornithorhynchus anatinus ENSOANG00000015497 I 0.781
XP_002157279.1 Hydra magnipapillata XP_002157279.1 I 0.775
smad9 Oryzias latipes ENSORLG00000003956 I 0.766
smad1 Danio rerio ENSDARG00000027199 I 0.766
smad5 Tetraodon nigroviridis ENSTNIG00000003701 I 0.766
TsM_000781600 Taenia solium TsM_000781600 I 0.766
TMUE_s0173000400 Trichuris muris TMUE_s0173000400 I 0.766
smad9 Danio rerio ENSDARG00000021938 I 0.766
ENSAPLG00000003593 Anas platyrhynchos ENSAPLG00000003593 I 0.766
smad1.L Xenopus laevis XB-GENE-1018199 I 0.766
smad1 Xenopus tropicalis XB-GENE-1018193 I 0.766
SMRZ_0000889701 Schistosoma margrebowiei SMRZ_0000889701 I 0.766
SMTD_0001194901 Schistosoma mattheei SMTD_0001194901 I 0.766
BGIBMGA010481 Bombyx mori BGIBMGA010481 I 0.766
smad1.S Xenopus laevis XB-GENE-6253892 I 0.766
BGLB010651 Biomphalaria glabrata BGLB010651 I 0.766
BGLB001215 Biomphalaria glabrata BGLB001215 I 0.766
SCUD_0000553301 Schistosoma curassoni SCUD_0000553301 I 0.766
SMU15035000 Schmidtea mediterranea SMU15035000 I 0.766
Sjc_0006780 Schistosoma japonicum Sjc_0006780 I 0.766
SMAD5 Ornithorhynchus anatinus ENSOANG00000009906 I 0.766
ENSPFOG00000015984 Poecilia formosa ENSPFOG00000015984 I 0.766
ENSPFOG00000015910 Poecilia formosa ENSPFOG00000015910 I 0.766
ENSAMXG00000016040 Astyanax mexicanus ENSAMXG00000016040 I 0.766
Ocbimv22036741m.g Octopus bimaculoides Ocbimv22036741m.g I 0.766
SROB_0000039301 Schistosoma rodhaini SROB_0000039301 I 0.766
DAPPUDRAFT_300607 Daphnia pulex DAPPUDRAFT_300607 I 0.766
ACYPI007984 Acyrthosiphon pisum ACYPI007984 I 0.766
ENSPFOG00000005752 Poecilia formosa ENSPFOG00000005752 I 0.766
ENSCSAG00000003430 Chlorocebus sabaeus ENSCSAG00000003430 I 0.766
Mad Drosophila melanogaster FBgn0011648 D 0.766
GE14935 Drosophila yakuba FBgn0232525 I 0.766
GF20577 Drosophila ananassae FBgn0097583 I 0.766
SMAR012602 Strigamia maritima SMAR012602 I 0.766
Smp_013060 Schistosoma mansoni Smp_013060 I 0.766
ENSXMAG00000016280 Xiphophorus maculatus ENSXMAG00000016280 I 0.766
GA28973 Drosophila pseudoobscura FBgn0250331 I 0.766
ENSLOCG00000008877 Lepisosteus oculatus ENSLOCG00000008877 I 0.766
ENSLOCG00000008478 Lepisosteus oculatus ENSLOCG00000008478 I 0.766
ENSTSYG00000000913 Tarsius syrichta ENSTSYG00000000913 I 0.766
SMAD1 Vicugna pacos ENSVPAG00000003340 I 0.766
HelroG185435 Helobdella robusta HelroG185435 I 0.766
GH10284 Drosophila grimshawi FBgn0117765 I 0.766
smad5 Takifugu rubripes ENSTRUG00000001329 I 0.766
GM18164 Drosophila sechellia FBgn0173071 I 0.766
GD22774 Drosophila simulans FBgn0194168 I 0.766
GL26531 Drosophila persimilis FBgn0164113 I 0.766
smad5 Gasterosteus aculeatus ENSGACG00000018718 I 0.766
GI17981 Drosophila mojavensis FBgn0140721 I 0.766
SPU_020722 Strongylocentrotus purpuratus SPU_020722 I 0.766
GJ19553 Drosophila virilis FBgn0206695 I 0.766
GG24457 Drosophila erecta FBgn0116589 I 0.766
SPU_023107 Strongylocentrotus purpuratus SPU_023107 I 0.766
TC014921 Tribolium castaneum TC014921 I 0.766
ENSXMAG00000008595 Xiphophorus maculatus ENSXMAG00000008595 I 0.766
GK18268 Drosophila willistoni FBgn0220267 I 0.766
PHUM033930 Pediculus humanus PHUM033930 I 0.760
NV10880 Nasonia vitripennis NV10880 I 0.752
ASTEI05192 Anopheles stephensi ASTEI05192 I 0.750
Aqu1.229822 Amphimedon queenslandica Aqu1.229822 I 0.750
Aqu1.228116 Amphimedon queenslandica Aqu1.228116 I 0.750
AQUA000239 Anopheles quadriannulatus AQUA000239 I 0.750
MCOS_0000603801 Mesocestoides corti MCOS_0000603801 I 0.750
ENSXMAG00000009618 Xiphophorus maculatus ENSXMAG00000009618 I 0.750
HmN_000160100 Hymenolepis microstoma HmN_000160100 I 0.750
ADAC002355 Anopheles darlingi ADAC002355 I 0.750
PPAI007902 Phlebotomus papatasi PPAI007902 I 0.750
MDOA015236 Musca domestica MDOA015236 I 0.750
MDOA012257 Musca domestica MDOA012257 I 0.750
LLOJ009024 Lutzomyia longipalpis LLOJ009024 I 0.750
AMIN001006 Anopheles minimus AMIN001006 I 0.750
AMEM010864 Anopheles merus AMEM010864 I 0.750
ACUA017601 Anopheles culicifacies ACUA017601 I 0.750
ACHR005633 Anopheles christyi ACHR005633 I 0.750
AEPI001857 Anopheles epiroticus AEPI001857 I 0.750
ACUA022001 Anopheles culicifacies ACUA022001 I 0.750
HNAJ_0000781101 Hymenolepis nana HNAJ_0000781101 I 0.750
AATE020501 Anopheles atroparvus AATE020501 I 0.750
AARA011030 Anopheles arabiensis AARA011030 I 0.750
AMAM023956 Anopheles maculatus AMAM023956 I 0.750
AMEC005585 Anopheles melas AMEC005585 I 0.750
AFUN010580 Anopheles funestus AFUN010580 I 0.750
AGAP008551 Anopheles gambiae AGAP008551 I 0.750
AALB000402 Anopheles albimanus AALB000402 I 0.750
ADIR010877 Anopheles dirus ADIR010877 I 0.750
CPIJ000420 Culex quinquefasciatus CPIJ000420 I 0.750
TASK_0000610701 Taenia asiatica TASK_0000610701 I 0.750
csin106589 Clonorchis sinensis csin106589 I 0.750
smad1 Takifugu rubripes ENSTRUG00000014344 I 0.750
smad1 Oryzias latipes ENSORLG00000007377 I 0.750
EmuJ_001018300 Echinococcus multilocularis EmuJ_001018300 I 0.750
ECPE_0001803101 Echinostoma caproni ECPE_0001803101 I 0.750
HDID_0000986701 Hymenolepis diminuta HDID_0000986701 I 0.750
ENSONIG00000010000 Oreochromis niloticus ENSONIG00000010000 I 0.750
smad9 Gasterosteus aculeatus ENSGACG00000020562 I 0.750
smad1 Gasterosteus aculeatus ENSGACG00000017230 I 0.750
TTAC_0000954401 Hydatigera taeniaeformis TTAC_0000954401 I 0.750
smad1 Tetraodon nigroviridis ENSTNIG00000017720 I 0.750
DILT_0000355601 Diphyllobothrium latum DILT_0000355601 I 0.750
CpipJ_CPIJ000420 Culex pipiens CpipJ_CPIJ000420 I 0.750
LDEC003904 Leptinotarsa decemlineata LDEC003904 I 0.750
smad5 Oryzias latipes ENSORLG00000009395 I 0.750
HMEL009295 Heliconius melpomene HMEL009295 I 0.750
ECANG7_02712 Echinococcus canadensis ECANG7_02712 I 0.750
CGI_10014747 Crassostrea gigas CGI_10014747 I 0.750
D915_05666 Fasciola hepatica D915_05666 I 0.750
SMAD3 Gasterosteus aculeatus ENSGACG00000016882 I 0.750
ENSPFOG00000024550 Poecilia formosa ENSPFOG00000024550 I 0.750
KGM_04785 Danaus plexippus KGM_04785 I 0.750
AAEL005513 Aedes aegypti AAEL005513 I 0.750
LCUP000453 Lucilia cuprina LCUP000453 I 0.750
LotgiG104873 Lottia gigantea LotgiG104873 I 0.750
T265_01150 Opisthorchis viverrini T265_01150 I 0.750
CLEC006591 Cimex lectularius CLEC006591 I 0.750
TMUE_s0005013500 Trichuris muris TMUE_s0005013500 I 0.743
D918_09504 Trichuris suis D918_09504 I 0.743
TTRE_0000192701 Trichuris trichiura TTRE_0000192701 I 0.743
csin108472 Clonorchis sinensis csin108472 I 0.734
ENSCING00000022875 Ciona intestinalis ENSCING00000022875 I 0.734
ENSOARG00000010293 Ovis aries ENSOARG00000010293 I 0.734
RPRC008357 Rhodnius prolixus RPRC008357 I 0.734
T265_03875 Opisthorchis viverrini T265_03875 I 0.734
HHAL000023-PA Halyomorpha halys HHAL000023-PA I 0.734
ML093050a Mnemiopsis leidyi ML093050a I 0.734
EFV60166 Trichinella spiralis EFV60166 I 0.733
D917_04509 Trichinella nativa D917_04509 I 0.733
ENSPPYG00000005285 Pongo abelii ENSPPYG00000005285 I 0.725
ENSCING00000006188 Ciona intestinalis ENSCING00000006188 I 0.723
estExt_fgenesh2_pm.C_1880004 Branchiostoma floridae estExt_fgenesh2_pm.C_1880004 I 0.719
SMAD5 Homo sapiens ENSG00000113658 D 0.719
SMU15039699 Schmidtea mediterranea SMU15039699 I 0.719
ENSCSAVG00000002875 Ciona savignyi ENSCSAVG00000002875 I 0.719
BGLB003972 Biomphalaria glabrata BGLB003972 I 0.719
estExt_fgenesh2_pg.C_20279 Branchiostoma floridae estExt_fgenesh2_pg.C_20279 I 0.719
SNAPOd2T00013556001 Oikopleura dioica SNAPOd2T00013556001 I 0.719
ADIR005117 Anopheles dirus ADIR005117 I 0.718
Aqu1.222022 Amphimedon queenslandica Aqu1.222022 I 0.717
SMAD9 Cavia porcellus ENSCPOG00000010255 I 0.716
smad9 Takifugu rubripes ENSTRUG00000001196 I 0.706
ENSAMXG00000016178 Astyanax mexicanus ENSAMXG00000016178 I 0.706
smad9 Tetraodon nigroviridis ENSTNIG00000009925 I 0.706
smad9.S Xenopus laevis XB-GENE-865114 I 0.706
SMAD9 Taeniopygia guttata ENSTGUG00000011897 I 0.703
TsM_000653100 Taenia solium TsM_000653100 I 0.703
TTAC_0000691201 Hydatigera taeniaeformis TTAC_0000691201 I 0.703
EmuJ_000893400 Echinococcus multilocularis EmuJ_000893400 I 0.703
L893_g15060 Steinernema glaseri L893_g15060 N 0.703
ECANG7_00782 Echinococcus canadensis ECANG7_00782 I 0.703
nRc.2.0.1.g14309 Romanomermis culicivorax nRc.2.0.1.g14309 N 0.703
SPAL_0001290200 Strongyloides papillosus SPAL_0001290200 N 0.703
MESCA008319 Megaselia scalaris MESCA008319 I 0.703
TASK_0000487901 Taenia asiatica TASK_0000487901 I 0.703
LDEC015977 Leptinotarsa decemlineata LDEC015977 I 0.700