TBX2 (Homo sapiens)
T-box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00907 (T-box) IPR001699 ENSG00000121068 T339889_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
TBX2
M03556_2.00		 Homo sapiens
GGTGTKADDWNTVACACB
VGTGTBANWHHTMACACC		 SELEX
Jolma et al.(2013)
TBX2_1		 (Direct) (Direct)
TBX2
M03557_2.00		 Homo sapiens
NAGGTGTBAWN
NWTVACACCTN		 SELEX
Jolma et al.(2013)
TBX2_2		 (Direct) (Direct)
TBX2
M05799_2.00		 Homo sapiens
NNVRCRCNNN
NNNGYGYBNN		 SELEX
Yin et al.(2017)
TBX2_eDBD_HT-SELEX		 (Direct) (Direct)
TBX2
M05800_2.00		 Homo sapiens
NNVRCRCBNN
NNVGYGYBNN		 SELEX
Yin et al.(2017)
TBX2_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)
TBX2
M11381_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TBX2_Q2		 (Direct) (Direct)
TBX2
M11382_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TBX2_Q5		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Tbx2
M00830_2.00 		Mus musculus
NYVDCACBHN
NDVGTGHBRN		 PBM
Weirauch et al.(2013)
pTH3751 		0.920 1.000
Tbx2
M08044_2.00 		Mus musculus
GCHYBCTGGGADHTGTAGTYH
DRACTACADHTCCCAGVRDGC		 ChIP-seq
Chen et al.(2011)
SRP001585_Tbx2 		0.920 1.000
Tbx3
M00834_2.00 		Mus musculus
NHNDCACNHN
NDNGTGHNDN		 PBM
Weirauch et al.(2013)
pTH3998 		0.906 0.950
TBX3
M05801_2.00 		Homo sapiens
NDSGTGTBRN
NYVACACSHN		 SELEX
Yin et al.(2017)
TBX3_eDBD_HT-SELEX 		0.906 0.950
TBX3
M09426_2.00 		Homo sapiens
DVDGGTGBNAR
YTNVCACCHBH		 Misc
Kulakovskiy et al.(2013)
TBX3_HUMAN.H11MO.0.C 		0.906 0.950
Tbx3
M09429_2.00 		Mus musculus
RRGGTGBBR
YVVCACCYY		 Misc
Kulakovskiy et al.(2013)
TBX3_MOUSE.H11MO.0.B 		0.906 0.950
TBX3
M05802_2.00 		Homo sapiens
DAGGTGTKAN
NTMACACCTH		 SELEX
Yin et al.(2017)
TBX3_eDBD_Methyl-HT-SELEX 		0.906 0.950
TBX2
M02495_2.00 		Gasterosteus aculeatus
NNVDCACNHN
NDNGTGHBNN		 PBM
Weirauch et al.(2014)
pTH9182 		0.887 0.972
TBX2
M02496_2.00 		Takifugu rubripes
DAGGTGTBRN
NYVACACCTH		 PBM
Weirauch et al.(2014)
pTH9289 		0.887 0.967
XP_008203914.1
M01029_2.00 		Nasonia vitripennis
AGGTGTBA
TVACACCT		 PBM
SebePedros et al.(2013)
pTH9336 		0.842 0.873
estExt_fgenesh2_pg.C_1570024
M01030_2.00 		Branchiostoma floridae
NHNDCACNHN
NDNGTGHNDN		 PBM
SebePedros et al.(2013)
pTH9244 		0.808 0.724
Tbx5
M00833_2.00 		Mus musculus
AGGTGTBA
TVACACCT		 PBM
Weirauch et al.(2013)
pTH3775 		0.799 0.657
TBX5
M03552_2.00 		Homo sapiens
AGGTGTBA
TVACACCT		 SELEX
Jolma et al.(2013)
TBX5_1 		0.799 0.657
TBX5
M03553_2.00 		Homo sapiens
AGGTGTKANWWNTVACACCT
AGGTGTBANWWNTMACACCT		 SELEX
Jolma et al.(2013)
TBX5_2 		0.799 0.657
Tbx5
M09649_2.00 		Mus musculus
AGGTGHBA
TVDCACCT		 Misc
Heinz et al.(2010)
HL1-Tbx5.biotin_GSE21529 		0.799 0.657
TBX5
M11374_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TBX5_01 		0.799 0.657
TBX5
M11375_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TBX5_02 		0.799 0.657
Tbx5
M11387_2.00 		Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TBX5_05 		0.799 0.657
TBX5
M11376_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TBX5_Q2 		0.799 0.657
TBX5
M11377_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TBX5_Q5 		0.799 0.657
Tbx4
M00831_2.00 		Mus musculus
AGGTGTBA
TVACACCT		 PBM
Weirauch et al.(2013)
pTH3973 		0.785 0.657
TBX4
M03558_2.00 		Homo sapiens
AGGTGTBA
TVACACCT		 SELEX
Jolma et al.(2013)
TBX4_1 		0.785 0.657
TBX4
M03559_2.00 		Homo sapiens
AGGTGTBANWWNTVACACBT
AVGTGTBANWWNTVACACCT		 SELEX
Jolma et al.(2013)
TBX4_2 		0.785 0.657
XP_001195863
M02498_2.00 		Strongylocentrotus purpuratus
AGGTGTBA
TVACACCT		 PBM
Weirauch et al.(2014)
pTH9340 		0.782 0.707
For this family, TFs with SR scores > 0.734 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000240328 T-box 107 287
ENSP00000404781 T-box 107 139

Links

Other T-box family TFs
Other Homo sapiens TFs

554 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
30006.m000282 Ricinus communis 30006.m000282 N 0.000
30170.m013669 Ricinus communis 30170.m013669 N 0.000
AMTR_s00159p00062070 Amborella trichopoda AMTR_s00159p00062070 N 0.000
Aquca_009_00241 Aquilegia coerulea Aquca_009_00241 N 0.000
AT2G41710 Arabidopsis thaliana AT2G41710 N 0.000
BGIOSGA019793 Oryza indica BGIOSGA019793 N 0.000
BGIOSGA023402 Oryza indica BGIOSGA023402 N 0.000
Bo3g035770 Brassica oleracea Bo3g035770 N 0.000
Bo4g013420 Brassica oleracea Bo4g013420 N 0.000
Bra004641 Brassica rapa Bra004641 N 0.000
BRADI2G26987 Brachypodium distachyon BRADI2G26987 N 0.000
Cagra.0914s0005 Capsella grandiflora Cagra.0914s0005 N 0.000
Carubv10023272m.g Capsella rubella Carubv10023272m.g N 0.000
cassava19560.m1 Manihot esculenta cassava19560.m1 N 0.000
cassava40681.m1 Manihot esculenta cassava40681.m1 N 0.000
cassava421.valid.m1 Manihot esculenta cassava421.valid.m1 N 0.000
Ca_07237 Cicer arietinum Ca_07237 N 0.000
chr3.CM0452.130.nd Lotus japonicus chr3.CM0452.130.nd N 0.000
Ciclev10005012m.g Citrus clementina Ciclev10005012m.g N 0.000
Cla022214 Citrullus lanatus Cla022214 N 0.000
Cucsa.338170 Cucumis sativus Cucsa.338170 N 0.000
Cucsa.353040 Cucumis sativus Cucsa.353040 I 0.000
Eucgr.A02341 Eucalyptus grandis Eucgr.A02341 N 0.000
evm.TU.supercontig_129.70 Carica papaya evm.TU.supercontig_129.70 N 0.000
evm.TU.supercontig_224.4 Carica papaya evm.TU.supercontig_224.4 N 0.000
evm.TU.supercontig_99.39 Carica papaya evm.TU.supercontig_99.39 N 0.000
F775_10869 Aegilops tauschii F775_10869 N 0.000
fgenesh2_kg.4__2311__AT2G41710.2 Arabidopsis lyrata fgenesh2_kg.4__2311__AT2G41710.2 N 0.000
gene02470-v1.0-hybrid Fragaria vesca gene02470-v1.0-hybrid N 0.000
GLYMA02G33090 Glycine max GLYMA02G33090 N 0.000
GLYMA03G29240 Glycine max GLYMA03G29240 N 0.000
GLYMA19G31960 Glycine max GLYMA19G31960 N 0.000
Gorai.003G091500 Gossypium raimondii Gorai.003G091500 N 0.000
GRMZM2G013657 Zea mays GRMZM2G013657 N 0.000
GRMZM2G146688 Zea mays GRMZM2G146688 N 0.000
LjSGA_012098.1 Lotus japonicus LjSGA_012098.1 N 0.000
LPERR05G11930 Leersia perrieri LPERR05G11930 N 0.000
Lus10000965.g Linum usitatissimum Lus10000965.g N 0.000
Lus10011730.g Linum usitatissimum Lus10011730.g N 0.000
Lus10039650.g Linum usitatissimum Lus10039650.g N 0.000
Lus10040140.g Linum usitatissimum Lus10040140.g N 0.000
MDP0000314518 Malus domestica MDP0000314518 N 0.000
MDP0000803527 Malus domestica MDP0000803527 N 0.000
mgf017600m Mimulus guttatus mgf017600m N 0.000
mgf019897m Mimulus guttatus mgf019897m N 0.000
MLOC_7325 Hordeum vulgare MLOC_7325 N 0.000
MTR_7g091390 Medicago truncatula MTR_7g091390 N 0.000
OB03G42600 Oryza brachyantha OB03G42600 N 0.000
OB05G22940 Oryza brachyantha OB05G22940 N 0.000
OB06G31060 Oryza brachyantha OB06G31060 N 0.000
OBART05G15060 Oryza barthii OBART05G15060 N 0.000
OBART06G23380 Oryza barthii OBART06G23380 N 0.000
OGLUM05G15890 Oryza glumaepatula OGLUM05G15890 N 0.000
OGLUM06G03000 Oryza glumaepatula OGLUM06G03000 N 0.000
OLONG_002212 Oryza longistaminata OLONG_002212 N 0.000
OLONG_020459 Oryza longistaminata OLONG_020459 N 0.000
OMERI05G13370 Oryza meridionalis OMERI05G13370 N 0.000
OMERI06G23370 Oryza meridionalis OMERI06G23370 N 0.000
ONIVA05G15390 Oryza nivara ONIVA05G15390 N 0.000
OPUNC05G13110 Oryza punctata OPUNC05G13110 N 0.000
orange1.1g018292m.g Citrus sinensis orange1.1g018292m.g N 0.000
ORGLA05G0129100 Oryza glaberrima ORGLA05G0129100 N 0.000
ORUFI05G16140 Oryza rufipogon ORUFI05G16140 N 0.000
Pavir.Ca01410 Panicum virgatum Pavir.Ca01410 N 0.000
Pavir.Cb01456 Panicum virgatum Pavir.Cb01456 N 0.000
PDK_20s1313371g002 Phoenix dactylifera PDK_20s1313371g002 N 0.000
PK12273.1 Cannabis sativa PK12273.1 N 0.000
PK15670.1 Cannabis sativa PK15670.1 N 0.000
PK18855.1 Cannabis sativa PK18855.1 N 0.000
POPTR_0006s04820 Populus trichocarpa POPTR_0006s04820 N 0.000
POPTR_0016s05670 Populus trichocarpa POPTR_0016s05670 N 0.000
PRUPE_ppa006202mg Prunus persica PRUPE_ppa006202mg N 0.000
SapurV1A.0037s0030 Salix purpurea SapurV1A.0037s0030 N 0.000
SapurV1A.3066s0020 Salix purpurea SapurV1A.3066s0020 N 0.000
Sb09g019190 Sorghum bicolor Sb09g019190 N 0.000
Si021952m.g Setaria italica Si021952m.g N 0.000
Solyc02g030210.2 Solanum lycopersicum Solyc02g030210.2 N 0.000
TCM_024554 Theobroma cacao TCM_024554 N 0.000
Thhalv10016812m.g Eutrema salsugineum Thhalv10016812m.g N 0.000
Traes_6AS_53FA034C9 Triticum aestivum Traes_6AS_53FA034C9 N 0.000
TRIUR3_07433 Triticum urartu TRIUR3_07433 N 0.000
BBM Vitis vinifera VIT_04s0023g00950 N 0.000
VIT_08s0007g08580 Vitis vinifera VIT_08s0007g08580 N 0.000