CIS-BP Database: Catalog of Inferred Sequence Binding Preferences

TF Information

tcf4 *(Xenopus tropicalis)* bHLH
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source
PF00010 (HLH)	IPR001092	XB-GENE-1011628	T051763_2.00	Misc (2018-Jan-19)
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
Tcf4 M01750_2.00	Mus musculus	VCAGVTGBN	NVCABCTGB	PBM Weirauch et al.(2014) pTH5101	0.914	1.000
TCF4 M02807_2.00	Homo sapiens	HRCACCTGBN	NVCAGGTGYD	SELEX Jolma et al.(2013) TCF4_1	0.914	1.000
TCF4 M02808_2.00	Homo sapiens	NVCACCTBBN	NVVAGGTGBN	SELEX Jolma et al.(2013) TCF4_2	0.914	1.000
TCF4 M02728_2.00	Homo sapiens	RCACCTG	CAGGTGY	SELEX Jolma et al.(2010) TCF4_dimer	0.914	1.000
TCF4 M04214_2.00	Homo sapiens	VCACCTGB	VCAGGTGB	SELEX Yin et al.(2017) TCF4_eDBD_HT-SELEX	0.914	1.000
Tcf4 M08775_2.00	Mus musculus	HRCACCTGB	VCAGGTGYD	Misc Kulakovskiy et al.(2013) ITF2_MOUSE.H11MO.0.B	0.914	1.000
TCF4 M09461_2.00	Homo sapiens	ASWTCAAAGRVN	NBYCTTTGAWST	Misc Heinz et al.(2010) Hct116-Tcf4_SRA012054	0.914	1.000
TCF4 M04215_2.00	Homo sapiens	VCACCTGN	NCAGGTGB	SELEX Yin et al.(2017) TCF4_eDBD_Methyl-HT-SELEX	0.914	1.000
Tcf12 M01740_2.00	Mus musculus	NVCAYCTGB	VCAGRTGBN	PBM Weirauch et al.(2014) pTH5071	0.912	0.962
TCF12 M04137_2.00	Homo sapiens	VCACSTGB	VCASGTGB	SELEX Yin et al.(2017) TCF12_eDBD_HT-SELEX	0.912	0.962
Tcf12 M08062_2.00	Mus musculus	RRCAGCTGNNN	NNNCAGCTGYY	ChIP-seq Mathelier et al.(2014) MA0521.1	0.912	0.962
TCF12 M07805_2.00	Homo sapiens	NVDSCAGSTGB	VCASCTGSHBN	ChIP-seq Gerstein et al.(2012) GM12878_TCF12_HudsonAlpha	0.912	0.962
TCF12 M07806_2.00	Homo sapiens	VCASCTGB	VCAGSTGB	ChIP-seq Gerstein et al.(2012) H1-hESC_TCF12_HudsonAlpha	0.912	0.962
TCF12 M08731_2.00	Homo sapiens	CMCASCTGSH	DSCAGSTGKG	Misc Kulakovskiy et al.(2013) HTF4_HUMAN.H11MO.0.A	0.912	0.962
Tcf12 M08762_2.00	Mus musculus	VMCASCTGSH	DSCAGSTGKB	Misc Kulakovskiy et al.(2013) HTF4_MOUSE.H11MO.0.A	0.912	0.962
TCF12 M09458_2.00	Homo sapiens	NNVCAGCTGB	VCAGCTGBNN	Misc Heinz et al.(2010) GM12878-Tcf12_GSE32465	0.912	0.962
TCF12 M09858_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$HEB_Q6	0.912	0.962
TCF12 M09859_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$HTF4_Q2	0.912	0.962
TCF12 M09860_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$TCF12_01	0.912	0.962
TCF12 M09861_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$TCF12_03	0.912	0.962
TCF12 M09862_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$TCF12_05	0.912	0.962
TCF12 M04138_2.00	Homo sapiens	NCAYCTGN	NCAGRTGN	SELEX Yin et al.(2017) TCF12_eDBD_Methyl-HT-SELEX	0.912	0.962
Tcf3 M00753_2.00	Mus musculus	VCACCTGBN	NVCAGGTGB	PBM Weirauch et al.(2013) pTH3866	0.912	0.885
Tcf3 M01723_2.00	Mus musculus	NNVCACSTGB	VCASGTGBNN	PBM Weirauch et al.(2014) pTH4580	0.912	0.885
Tcf3 M00118_2.00	Mus musculus	VCAYCTGB	VCAGRTGB	PBM Badis et al.(2009) Tcfe2a_3865	0.912	0.885
Tcf3 M09465_2.00	Mus musculus	ABWTCAAAGS	SCTTTGAWVT	Misc Heinz et al.(2010) mES-Tcf3_GSE11724	0.884	0.923
Tcf3 M09466_2.00	Mus musculus	VCAGCTGBNN	NNVCAGCTGB	Misc Heinz et al.(2010) proBcell-E2A_GSE21978	0.884	0.923
Tcf3 M09886_2.00	Mus musculus	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$E47_05	0.884	0.923
TCF3 M02775_2.00	Homo sapiens	NVCACCTGBN	NVCAGGTGBN	SELEX Jolma et al.(2013) TCF3_1	0.884	0.885
TCF3 M08710_2.00	Homo sapiens	VVCASCTGCHN	NDGCAGSTGBB	Misc Kulakovskiy et al.(2013) TFE2_HUMAN.H11MO.0.A	0.884	0.885
TCF3 M09791_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$E12_Q6	0.884	0.885
TCF3 M09792_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$E2A_Q6_01	0.884	0.885
TCF3 M09793_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$E2A_Q6_02	0.884	0.885
TCF3 M09794_2.00	Homo sapiens	VVVVMCACCTGCNBB	VVNGCAGGTGKBBBB	Transfac Matys et al.(2006) V$E47_01	0.884	0.885
TCF3 M09795_2.00	Homo sapiens	NNKWRCACCTGYDNNN	NNNHRCAGGTGYWMNN	Transfac Matys et al.(2006) V$E47_02	0.884	0.885
For this family, TFs with SR scores > 0.838* will likely have a similar motif*

DNA Binding Domains

Protein ID	Domain	From	To	Sequence
AAI21472	bHLH	563	616	RRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLE

Links
Other bHLH family TFs
Other *Xenopus tropicalis* TFs

212 Related TFs

Name	Species	Gene ID	Motif Evidence	SR Score	Action
NV16594	Nasonia vitripennis	NV16594	I	0.000
CpipJ_CPIJ006378	Culex pipiens	CpipJ_CPIJ006378	N	0.000
AAEL002343	Aedes aegypti	AAEL002343	N	0.000
AAEL014740	Aedes aegypti	AAEL014740	N	0.000
ACEP14936	Atta cephalotes	ACEP14936	N	0.000
ACYPI001635	Acyrthosiphon pisum	ACYPI001635	N	0.000
ADAC003908	Anopheles darlingi	ADAC003908	N	0.000
AGAP000056	Anopheles gambiae	AGAP000056	N	0.000
CGI_10014877	Crassostrea gigas	CGI_10014877	N	0.000
CPIJ006378	Culex quinquefasciatus	CPIJ006378	N	0.000
DAPPUDRAFT_59022	Daphnia pulex	DAPPUDRAFT_59022	N	0.000
ENSAMEG00000018716	Ailuropoda melanoleuca	ENSAMEG00000018716	N	0.000
ENSAPLG00000000714	Anas platyrhynchos	ENSAPLG00000000714	N	0.000
NPAS1	Bos taurus	ENSBTAG00000015576	N	0.000
NPAS1	Canis familiaris	ENSCAFG00000032405	N	0.000
NPAS3	Choloepus hoffmanni	ENSCHOG00000013756	N	0.000
NPAS3	Callithrix jacchus	ENSCJAG00000005437	N	0.000
NPAS1	Callithrix jacchus	ENSCJAG00000011666	N	0.000
NPAS3	Cavia porcellus	ENSCPOG00000006976	N	0.000
NPAS1	Cavia porcellus	ENSCPOG00000023069	N	0.000
ENSCSAG00000003006	Chlorocebus sabaeus	ENSCSAG00000003006	N	0.000
NPAS1	Dasypus novemcinctus	ENSDNOG00000035321	N	0.000
Npas3	Dipodomys ordii	ENSDORG00000000860	N	0.000
ENSECAG00000004630	Equus caballus	ENSECAG00000004630	N	0.000
NPAS3	Erinaceus europaeus	ENSEEUG00000006528	N	0.000
NPAS3	Echinops telfairi	ENSETEG00000016603	N	0.000
NPAS1	Felis catus	ENSFCAG00000004833	N	0.000
NPAS1	Homo sapiens	ENSG00000130751	N	0.000
NPAS3	Homo sapiens	ENSG00000151322	N	0.000
NPAS3	Gallus gallus	ENSGALG00000029022	N	0.000
NPAS1	Gorilla gorilla	ENSGGOG00000013398	N	0.000
NPAS3	Gorilla gorilla	ENSGGOG00000022941	N	0.000
ENSLACG00000001145	Latimeria chalumnae	ENSLACG00000001145	N	0.000
NPAS3	Loxodonta africana	ENSLAFG00000007169	N	0.000
ENSMEUG00000000606	Macropus eugenii	ENSMEUG00000000606	N	0.000
ENSMEUG00000012966	Macropus eugenii	ENSMEUG00000012966	N	0.000
ENSMGAG00000016559	Meleagris gallopavo	ENSMGAG00000016559	N	0.000
NPAS1	Microcebus murinus	ENSMICG00000006346	N	0.000
NPAS1	Macaca mulatta	ENSMMUG00000011330	N	0.000
NPAS3	Macaca mulatta	ENSMMUG00000014839	N	0.000
NPAS1	Monodelphis domestica	ENSMODG00000009053	N	0.000
ENSMODG00000024103	Monodelphis domestica	ENSMODG00000024103	N	0.000
ENSMPUG00000001046	Mustela putorius furo	ENSMPUG00000001046	N	0.000
ENSMPUG00000005118	Mustela putorius furo	ENSMPUG00000005118	N	0.000
Npas1	Mus musculus	ENSMUSG00000001988	N	0.000
Npas3	Mus musculus	ENSMUSG00000021010	N	0.000
ENSNLEG00000002946	Nomascus leucogenys	ENSNLEG00000002946	N	0.000
ENSNLEG00000003239	Nomascus leucogenys	ENSNLEG00000003239	N	0.000
ENSOANG00000014043	Ornithorhynchus anatinus	ENSOANG00000014043	N	0.000
ENSOARG00000010869	Ovis aries	ENSOARG00000010869	N	0.000
NPAS1	Otolemur garnettii	ENSOGAG00000012829	N	0.000
NPAS3	Otolemur garnettii	ENSOGAG00000014886	N	0.000
NPAS3	Ochotona princeps	ENSOPRG00000008184	N	0.000
NPAS1	Ochotona princeps	ENSOPRG00000014860	N	0.000
ENSPANG00000014704	Papio anubis	ENSPANG00000014704	N	0.000
ENSPCAG00000000784	Procavia capensis	ENSPCAG00000000784	N	0.000
NPAS3	Procavia capensis	ENSPCAG00000007391	N	0.000
ENSPPYG00000010165	Pongo abelii	ENSPPYG00000010165	N	0.000
ENSPSIG00000017052	Pelodiscus sinensis	ENSPSIG00000017052	N	0.000
NPAS3	Pan troglodytes	ENSPTRG00000006249	N	0.000
NPAS1	Pan troglodytes	ENSPTRG00000011199	N	0.000
Npas1	Rattus norvegicus	ENSRNOG00000015376	N	0.000
NPAS3	Sorex araneus	ENSSARG00000003164	N	0.000
ENSSARG00000014127	Sorex araneus	ENSSARG00000014127	N	0.000
ENSSHAG00000011475	Sarcophilus harrisii	ENSSHAG00000011475	N	0.000
NPAS1	Sus scrofa	ENSSSCG00000003108	N	0.000
ENSSSCG00000024473	Sus scrofa	ENSSSCG00000024473	N	0.000
ENSSTOG00000003396	Ictidomys tridecemlineatus	ENSSTOG00000003396	N	0.000
ENSSTOG00000014736	Ictidomys tridecemlineatus	ENSSTOG00000014736	N	0.000
NPAS3	Tupaia belangeri	ENSTBEG00000016041	N	0.000
ENSTGUG00000011911	Taeniopygia guttata	ENSTGUG00000011911	N	0.000
NPAS3	Tursiops truncatus	ENSTTRG00000003266	N	0.000
NPAS1	Tursiops truncatus	ENSTTRG00000011416	N	0.000
NPAS3	Vicugna pacos	ENSVPAG00000001108	N	0.000
trh	Drosophila sechellia	FBgn0025046	N	0.000
GA19928	Drosophila pseudoobscura	FBgn0079924	N	0.000
GF24890	Drosophila ananassae	FBgn0101882	N	0.000
GG14662	Drosophila erecta	FBgn0106918	N	0.000
GH15456	Drosophila grimshawi	FBgn0122928	N	0.000
GH23748	Drosophila grimshawi	FBgn0131205	N	0.000
GI16736	Drosophila mojavensis	FBgn0139484	N	0.000
GD25707	Drosophila simulans	FBgn0196992	N	0.000
GJ12482	Drosophila virilis	FBgn0199724	N	0.000
GK20151	Drosophila willistoni	FBgn0222148	N	0.000
GE21022	Drosophila yakuba	FBgn0238304	N	0.000
trh	Drosophila melanogaster	FBgn0262139	N	0.000
GB52114	Apis mellifera	GB52114	N	0.000
HelroG63031	Helobdella robusta	HelroG63031	N	0.000
ISCW018625	Ixodes scapularis	ISCW018625	N	0.000
L798_01241	Zootermopsis nevadensis	L798_01241	N	0.000
LotgiG127403	Lottia gigantea	LotgiG127403	N	0.000
MCINX015160	Melitaea cinxia	MCINX015160	N	0.000
NEMVEDRAFT_v1g96877	Nematostella vectensis	NEMVEDRAFT_v1g96877	N	0.000
NV13641	Nasonia vitripennis	NV13641	N	0.000
PHUM613040	Pediculus humanus	PHUM613040	N	0.000
SMAR015279	Strigamia maritima	SMAR015279	N	0.000
SPU_014249	Strongylocentrotus purpuratus	SPU_014249	N	0.000
TC001448	Tribolium castaneum	TC001448	N	0.000
tetur01g16040	Tetranychus urticae	tetur01g16040	N	0.000
Aan_R007988	Calypte anna	Aan_R007988	N	0.000
Afo_R000495	Aptenodytes forsteri	Afo_R000495	N	0.000
Brh_R013374	Buceros rhinoceros	Brh_R013374	N	0.000
Cflo_02462--XP_391937.2_APIME	Camponotus floridanus	Cflo_02462--XP_391937.2_APIME	N	0.000
ENSP00000348460-D1	Bos grunniens	ENSP00000348460-D1	N	0.000
ENSP00000348460	Macaca fascicularis	ENSP00000348460	N	0.000
ENSP00000405290	Macaca fascicularis	ENSP00000405290	N	0.000
Gfo_R012966	Geospiza fortis	Gfo_R012966	N	0.000
Hsal_10736--XP_391937.2_APIME	Harpegnathos saltator	Hsal_10736--XP_391937.2_APIME	N	0.000
Pvit_04747	Pogona vitticeps	Pvit_04747	N	0.000
Tal_R006980	Tyto alba	Tal_R006980	N	0.000
gw.84.113.1	Branchiostoma floridae	gw.84.113.1	N	0.000
Ocbimv22029779m.g	Octopus bimaculoides	Ocbimv22029779m.g	N	0.000
Sakowv30006415m.g	Saccoglossus kowalevskii	Sakowv30006415m.g	N	0.000
CLEC007310	Cimex lectularius	CLEC007310	N	0.000
LCUP010821	Lucilia cuprina	LCUP010821	N	0.000
LDEC011477	Leptinotarsa decemlineata	LDEC011477	N	0.000
npas3	Xenopus tropicalis	XB-GENE-999791	N	0.000
AALB007750	Anopheles albimanus	AALB007750	N	0.000
AARA001122	Anopheles arabiensis	AARA001122	N	0.000
AATE003730	Anopheles atroparvus	AATE003730	N	0.000
ACOM029080	Anopheles coluzzii	ACOM029080	N	0.000
ACUA021406	Anopheles culicifacies	ACUA021406	N	0.000
ADIR001051	Anopheles dirus	ADIR001051	N	0.000
AEPI007278	Anopheles epiroticus	AEPI007278	N	0.000
AFAF017713	Anopheles farauti	AFAF017713	N	0.000
AFUN004699	Anopheles funestus	AFUN004699	N	0.000
AMAM000698	Anopheles maculatus	AMAM000698	N	0.000
AMEC022213	Anopheles melas	AMEC022213	N	0.000
AMEM001368	Anopheles merus	AMEM001368	N	0.000
AMIN002121	Anopheles minimus	AMIN002121	N	0.000
AQUA005712	Anopheles quadriannulatus	AQUA005712	N	0.000
ASIS013948	Anopheles sinensis	ASIS013948	N	0.000
ASTEI06194	Anopheles stephensi	ASTEI06194	N	0.000
MDOA009035	Musca domestica	MDOA009035	N	0.000

tcf4 (Xenopus tropicalis) bHLH

TF Information

Directly determined binding motifs

Motifs from related TFs

DNA Binding Domains

Links

212 Related TFs

tcf4 **(Xenopus tropicalis)
bHLH**