klf4 (Xenopus tropicalis)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00096 (zf-C2H2) IPR007087 XB-GENE-1015049 T145353_2.00 Misc (2018-Jan-19)

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
KLF4
M04463_2.00 		Homo sapiens
NVCCACRCCCH
DGGGYGTGGBN		 SELEX
Yin et al.(2017)
KLF4_eDBD_HT-SELEX 		0.820 0.971
KLF4
M08091_2.00 		Homo sapiens
MCACACCCWNN
NNWGGGTGTGK		 ChIP-seq
Mathelier et al.(2014)
MA0039.3 		0.820 0.971
Klf4
M08021_2.00 		Mus musculus
VRCCMCRCCCH
DGGGYGKGGYB		 ChIP-seq
Chen et al.(2011)
SRP000217_Klf4 		0.820 0.971
KLF4
M08243_2.00 		Homo sapiens
RCCMCRCCCH
DGGGYGKGGY		 ChIP-seq
Najafabadi et al.(2015b)
KLF14 		0.820 0.971
KLF4
M08894_2.00 		Homo sapiens
RCCMCRCCCH
DGGGYGKGGY		 Misc
Kulakovskiy et al.(2013)
KLF4_HUMAN.H11MO.0.A 		0.820 0.971
Klf4
M08964_2.00 		Mus musculus
GCCMCRCCCWBYBBN
NVVRVWGGGYGKGGC		 Misc
Kulakovskiy et al.(2013)
KLF4_MOUSE.H11MO.0.A 		0.820 0.971
KLF4
M10217_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GKLF_02 		0.820 0.971
KLF4
M10218_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GKLF_Q3_01 		0.820 0.971
KLF4
M10219_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GKLF_Q3 		0.820 0.971
KLF4
M10220_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GKLF_Q4 		0.820 0.971
KLF4
M04464_2.00 		Homo sapiens
NVCCMCRCCCN
NGGGYGKGGBN		 SELEX
Yin et al.(2017)
KLF4_eDBD_Methyl-HT-SELEX 		0.820 0.971
KLF2
M04455_2.00 		Homo sapiens
NVCCMCRCCCH
DGGGYGKGGBN		 SELEX
Yin et al.(2017)
KLF2_eDBD_HT-SELEX 		0.813 0.942
KLF2
M10210_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$LKLF_Q3 		0.813 0.942
KLF2
M10211_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$LKLF_Q6 		0.813 0.942
KLF2
M04456_2.00 		Homo sapiens
NVCCMCRCCCN
NGGGYGKGGBN		 SELEX
Yin et al.(2017)
KLF2_eDBD_Methyl-HT-SELEX 		0.813 0.942
KLF1
M00226_2.00 		Homo sapiens
CMCGCCCM
KGGGCGKG		 PBM
Barrera et al.(2016)
KLF1_REF 		0.784 0.884
KLF1
M08293_2.00 		Homo sapiens
NVNNNRCCMCRCCCH
DGGGYGKGGYNNNBN		 ChIP-seq
Schmitges et al.(2016)
Q13351.MEME 		0.784 0.884
KLF1
M08871_2.00 		Homo sapiens
SVNDGCCMCRCCCH
DGGGYGKGGCHNBS		 Misc
Kulakovskiy et al.(2013)
KLF1_HUMAN.H11MO.0.A 		0.784 0.884
KLF1
M10163_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$EKLF_Q5_01 		0.784 0.884
KLF1
M10164_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$EKLF_Q5 		0.784 0.884
KLF1
M00224_2.00 		Homo sapiens
YMCGCCCH
DGGGCGKR		 PBM
Barrera et al.(2016)
KLF1_H299Y 		0.784 0.870
Klf1
M08099_2.00 		Mus musculus
NRCCACACCCW
WGGGTGTGGYN		 ChIP-seq
Mathelier et al.(2014)
MA0493.1 		0.781 0.855
Klf1
M09008_2.00 		Mus musculus
MVMNSCCMCRCCCH
DGGGYGKGGSNKBK		 Misc
Kulakovskiy et al.(2013)
KLF1_MOUSE.H11MO.0.A 		0.781 0.855
Klf1
M09516_2.00 		Mus musculus
DRCCACACCCWN
NWGGGTGTGGYH		 Misc
Heinz et al.(2010)
Erythrocyte-Klf1_GSE20478 		0.781 0.855
KLF5
M04410_2.00 		Homo sapiens
NMCACRCCCH
DGGGYGTGKN		 SELEX
Yin et al.(2017)
KLF5_eDBD_HT-SELEX 		0.781 0.826
KLF5
M08086_2.00 		Homo sapiens
BCCMCDCCCH
DGGGHGKGGV		 ChIP-seq
Mathelier et al.(2014)
MA0599.1 		0.781 0.826
KLF5
M08868_2.00 		Homo sapiens
NHVNRCCMCDCCCH
DGGGHGKGGYNBDN		 Misc
Kulakovskiy et al.(2013)
KLF5_HUMAN.H11MO.0.A 		0.781 0.826
Klf5
M08965_2.00 		Mus musculus
KCCMCDCCCHBBBCH
DGVVVDGGGHGKGGM		 Misc
Kulakovskiy et al.(2013)
KLF5_MOUSE.H11MO.0.A 		0.781 0.826
KLF5
M09502_2.00 		Homo sapiens
GCCMCRCCCH
DGGGYGKGGC		 Misc
Heinz et al.(2010)
LoVo-KLF5_GSE49402 		0.781 0.826
KLF5
M10149_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$BTEB2_Q3_01 		0.781 0.826
KLF5
M10150_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$BTEB2_Q3 		0.781 0.826
KLF5
M04411_2.00 		Homo sapiens
NMCACRCCYH
DRGGYGTGKN		 SELEX
Yin et al.(2017)
KLF5_eDBD_Methyl-HT-SELEX 		0.781 0.826
KLF3
M04418_2.00 		Homo sapiens
RRCCRCGCCCH
DGGGCGYGGYY		 SELEX
Yin et al.(2017)
KLF3_FL_HT-SELEX 		0.781 0.812
KLF3
M08876_2.00 		Homo sapiens
NSNNVCCMCRCCCHBBBBN
NVVVVDGGGYGKGGBNNSN		 Misc
Kulakovskiy et al.(2013)
KLF3_HUMAN.H11MO.0.B 		0.781 0.812
Klf3
M08982_2.00 		Mus musculus
NSNNVCCMCRCCCHBBBBN
NVVVVDGGGYGKGGBNNSN		 Misc
Kulakovskiy et al.(2013)
KLF3_MOUSE.H11MO.0.A 		0.781 0.812
KLF3
M10172_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$KLF3_Q3_01 		0.781 0.812
KLF3
M10173_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$KLF3_Q3 		0.781 0.812
KLF3
M04419_2.00 		Homo sapiens
DRCCACGCCCH
DGGGCGTGGYH		 SELEX
Yin et al.(2017)
KLF3_FL_Methyl-HT-SELEX_1 		0.781 0.812
KLF3
M04420_2.00 		Homo sapiens
RRSCGCARCCCN
NGGGYTGCGSYY		 SELEX
Yin et al.(2017)
KLF3_FL_Methyl-HT-SELEX_2 		0.781 0.812
Klf7
M00134_2.00 		Mus musculus
NHHMCRCCCH
DGGGYGKDDN		 PBM
Badis et al.(2009)
Klf7_0974 		0.765 0.812
luna
M03704_2.00 		Drosophila melanogaster
RCCACRCCCH
DGGGYGTGGY		 SELEX
Nitta et al.(2015)
luna_1 		0.765 0.812
luna
M06163_2.00 		Drosophila melanogaster
RRMHMCRCCC
GGGYGKDKYY		 B1H
Zhu et al.(2011)
luna_SANGER_5_FBgn0040765 		0.765 0.812
luna
M06164_2.00 		Drosophila melanogaster
DRCCMCGCCCHNNN
NNNDGGGCGKGGYH		 B1H
Zhu et al.(2011)
luna_SOLEXA_5_FBgn0040765 		0.765 0.812
KLF7
M08298_2.00 		Homo sapiens
VVCHMCGCCCH
DGGGCGKDGBB		 ChIP-seq
Schmitges et al.(2016)
O75840.MEME 		0.765 0.812
KLF6
M04400_2.00 		Homo sapiens
NVMCACRCCCH
DGGGYGTGKBN		 SELEX
Yin et al.(2017)
KLF6_eDBD_HT-SELEX 		0.765 0.797
KLF6
M08857_2.00 		Homo sapiens
BYBYVNBCYMCDCCCYBBN
NVVRGGGHGKRGVNBRVRV		 Misc
Kulakovskiy et al.(2013)
KLF6_HUMAN.H11MO.0.A 		0.765 0.797
Klf6
M08962_2.00 		Mus musculus
BYBYVNBCYMCDCCCYBBN
NVVRGGGHGKRGVNBRVRV		 Misc
Kulakovskiy et al.(2013)
KLF6_MOUSE.H11MO.0.B 		0.765 0.797
KLF6
M10113_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CPBP_Q6 		0.765 0.797
KLF6
M04401_2.00 		Homo sapiens
NRCCACGCCCH
DGGGCGTGGYN		 SELEX
Yin et al.(2017)
KLF6_eDBD_Methyl-HT-SELEX 		0.765 0.797
Klf12
M00787_2.00 		Mus musculus
NNHMCRCCCH
DGGGYGKDNN		 PBM
Weirauch et al.(2013)
pTH0977 		0.758 0.797
Klf12
M02937_2.00 		Mus musculus
GRCCACGCCCWHHHN
NDDDWGGGCGTGGYC		 SELEX
Jolma et al.(2013)
Klf12_1 		0.758 0.797
KLF12
M04430_2.00 		Homo sapiens
DRCCACGCCCH
DGGGCGTGGYH		 SELEX
Yin et al.(2017)
KLF12_FL_HT-SELEX 		0.758 0.797
KLF12
M08299_2.00 		Homo sapiens
SBNVGCCMCGCCCHB
VDGGGCGKGGCBNVS		 ChIP-seq
Schmitges et al.(2016)
Q9Y4X4.MEME 		0.758 0.797
KLF12
M08879_2.00 		Homo sapiens
GCCCCGCCCYB
VRGGGCGGGGC		 Misc
Kulakovskiy et al.(2013)
KLF12_HUMAN.H11MO.0.C 		0.758 0.797
KLF12
M10186_2.00 		Homo sapiens
HMYACDG
CHGTRKD		 Transfac
Matys et al.(2006)
V$AP2REP_01 		0.758 0.797
KLF12
M04431_2.00 		Homo sapiens
RGSCGACGCCCN
NGGGCGTCGSCY		 SELEX
Yin et al.(2017)
KLF12_FL_Methyl-HT-SELEX_1 		0.758 0.797
KLF12
M04432_2.00 		Homo sapiens
NRCCACGCCCH
DGGGCGTGGYN		 SELEX
Yin et al.(2017)
KLF12_FL_Methyl-HT-SELEX_2 		0.758 0.797
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
AAI25672 C2H2 ZF 335 359
AAI25672 C2H2 ZF 365 389
AAI25672 C2H2 ZF 395 417
AAI70893 C2H2 ZF 324 348
AAI70893 C2H2 ZF 354 378
AAI70893 C2H2 ZF 384 406
AAI70895 C2H2 ZF 324 348
AAI70895 C2H2 ZF 354 378
AAI70895 C2H2 ZF 384 406
CAJ81544 C2H2 ZF 324 348
CAJ81544 C2H2 ZF 354 378
CAJ81544 C2H2 ZF 384 406

Links

Other C2H2 ZF family TFs
Other Xenopus tropicalis TFs

644 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
KLF15 Homo sapiens ENSG00000163884 D
Klf15 Mus musculus ENSMUSG00000030087 D
cbt Drosophila melanogaster FBgn0043364 D
Aqu1.224794 Amphimedon queenslandica Aqu1.224794 I
CapteG30437 Capitella teleta CapteG30437 I
CGI_10020309 Crassostrea gigas CGI_10020309 I
DAPPUDRAFT_50068 Daphnia pulex DAPPUDRAFT_50068 I
ENSACAG00000012356 Anolis carolinensis ENSACAG00000012356 I
ENSAMEG00000006403 Ailuropoda melanoleuca ENSAMEG00000006403 I
ENSAMXG00000003461 Astyanax mexicanus ENSAMXG00000003461 I
ENSAMXG00000012874 Astyanax mexicanus ENSAMXG00000012874 I
ENSAMXG00000016240 Astyanax mexicanus ENSAMXG00000016240 I
ENSAPLG00000012971 Anas platyrhynchos ENSAPLG00000012971 I
KLF15 Bos taurus ENSBTAG00000008313 I
KLF15 Canis familiaris ENSCAFG00000003807 I
KLF15 Callithrix jacchus ENSCJAG00000006941 I
KLF15 Cavia porcellus ENSCPOG00000005315 I
ENSCSAG00000008037 Chlorocebus sabaeus ENSCSAG00000008037 I
si:ch211-117k10.3 Danio rerio ENSDARG00000090914 I
klf15 Danio rerio ENSDARG00000091127 I
KLF15 Dasypus novemcinctus ENSDNOG00000036157 I
ENSDORG00000016283 Dipodomys ordii ENSDORG00000016283 I
KLF15 Equus caballus ENSECAG00000021092 I
ENSFALG00000012601 Ficedula albicollis ENSFALG00000012601 I
klf15 Gasterosteus aculeatus ENSGACG00000003717 I
KLF15 Gasterosteus aculeatus ENSGACG00000011317 I
ENSGALG00000006245 Gallus gallus ENSGALG00000006245 I
ENSGALG00000021702 Gallus gallus ENSGALG00000021702 I
KLF15 Gorilla gorilla ENSGGOG00000009916 I
ENSGMOG00000000921 Gadus morhua ENSGMOG00000000921 I
ENSGMOG00000003751 Gadus morhua ENSGMOG00000003751 I
ENSLACG00000009512 Latimeria chalumnae ENSLACG00000009512 I
ENSLACG00000013240 Latimeria chalumnae ENSLACG00000013240 I
KLF15 Loxodonta africana ENSLAFG00000011970 I
ENSLOCG00000011807 Lepisosteus oculatus ENSLOCG00000011807 I
ENSLOCG00000013716 Lepisosteus oculatus ENSLOCG00000013716 I
ENSMGAG00000003006 Meleagris gallopavo ENSMGAG00000003006 I
KLF15 Meleagris gallopavo ENSMGAG00000007616 I
KLF15 Myotis lucifugus ENSMLUG00000010178 I
KLF15 Macaca mulatta ENSMMUG00000003721 I
ENSMPUG00000017390 Mustela putorius furo ENSMPUG00000017390 I
KLF15 Ornithorhynchus anatinus ENSOANG00000014825 I
KLF15 Oryctolagus cuniculus ENSOCUG00000012493 I
KLF15 Otolemur garnettii ENSOGAG00000000703 I
ENSONIG00000003215 Oreochromis niloticus ENSONIG00000003215 I
ENSONIG00000009164 Oreochromis niloticus ENSONIG00000009164 I
KLF15 Ochotona princeps ENSOPRG00000005237 I
klf15 Oryzias latipes ENSORLG00000001165 I
si:ch211-117k10.3 Oryzias latipes ENSORLG00000012237 I
ENSPANG00000026096 Papio anubis ENSPANG00000026096 I
KLF15 Procavia capensis ENSPCAG00000006301 I
ENSPFOG00000002472 Poecilia formosa ENSPFOG00000002472 I
ENSPFOG00000003698 Poecilia formosa ENSPFOG00000003698 I
ENSPFOG00000012815 Poecilia formosa ENSPFOG00000012815 I
ENSPPYG00000013455 Pongo abelii ENSPPYG00000013455 I
KLF15 Pan troglodytes ENSPTRG00000015329 I
KLF15 Pteropus vampyrus ENSPVAG00000004109 I
Klf15 Rattus norvegicus ENSRNOG00000017808 I
ENSSHAG00000007635 Sarcophilus harrisii ENSSHAG00000007635 I
si:ch211-117k10.3 Tetraodon nigroviridis ENSTNIG00000007382 I
si:ch211-117k10.3 Takifugu rubripes ENSTRUG00000000076 I
KLF15 Takifugu rubripes ENSTRUG00000006529 I
klf15 Takifugu rubripes ENSTRUG00000014976 I
KLF15 Tursiops truncatus ENSTTRG00000008498 I
ENSXMAG00000001323 Xiphophorus maculatus ENSXMAG00000001323 I
ENSXMAG00000007908 Xiphophorus maculatus ENSXMAG00000007908 I
ENSXMAG00000013094 Xiphophorus maculatus ENSXMAG00000013094 I
cbt Drosophila pseudoobscura FBgn0078183 I
cbt Drosophila ananassae FBgn0101744 I
cbt Drosophila erecta FBgn0116778 I
cbt Drosophila grimshawi FBgn0117994 I
cbt Drosophila mojavensis FBgn0140770 I
cbt Drosophila sechellia FBgn0171577 I
cbt Drosophila simulans FBgn0194348 I
cbt Drosophila virilis FBgn0206865 I
cbt Drosophila willistoni FBgn0226609 I
cbt Drosophila yakuba FBgn0233632 I
L798_11927 Zootermopsis nevadensis L798_11927 I
LotgiG100140 Lottia gigantea LotgiG100140 I
NEMVEDRAFT_v1g82548 Nematostella vectensis NEMVEDRAFT_v1g82548 I
SPU_015772 Strongylocentrotus purpuratus SPU_015772 I
YQE_06283 Dendroctonus ponderosae YQE_06283 I
Aan_R004458 Calypte anna Aan_R004458 I
Afo_R011755 Aptenodytes forsteri Afo_R011755 I
Alligator_sinensis_CCG003669.1 Alligator sinensis Alligator_sinensis_CCG003669.1 I
Alligator_sinensis_CCG019865.1 Alligator sinensis Alligator_sinensis_CCG019865.1 I
Brh_R002160 Buceros rhinoceros Brh_R002160 I
Cmyd_10010595 Chelonia mydas Cmyd_10010595 I
Cmyd_10013831 Chelonia mydas Cmyd_10013831 I
ENSP00000296233 Macaca fascicularis ENSP00000296233 I
Gfo_R014652 Geospiza fortis Gfo_R014652 I
Ogr01993 Ophisaurus gracilis Ogr01993 I
Ogr18174 Ophisaurus gracilis Ogr18174 I
Pvit_06090 Pogona vitticeps Pvit_06090 I
Pvit_11468 Pogona vitticeps Pvit_11468 I
Tal_R002960 Tyto alba Tal_R002960 I
Tal_R006156 Tyto alba Tal_R006156 I
gw.37.333.1 Branchiostoma floridae gw.37.333.1 I
gw.442.76.1 Branchiostoma floridae gw.442.76.1 I
Ocbimv22012776m.g Octopus bimaculoides Ocbimv22012776m.g I
Sakowv30044439m.g Saccoglossus kowalevskii Sakowv30044439m.g I
klf15.2 Xenopus tropicalis XB-GENE-1018580 I
klf15 Xenopus tropicalis XB-GENE-854149 I
klf15.S Xenopus laevis XB-GENE-854150 I