mab-3 (Caenorhabditis elegans)
DM

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00751 (DM) IPR001275 WBGene00003100 T169430_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II; nematode male tail tip morphogenesis; and positive regulation of nematode male tail tip morphogenesis. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including SMDVL; head neurons; intestine; ray neurons; and tail. [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
mab-3
M00653_2.00		 Caenorhabditis elegans
NWTGTTGCRN
NYGCAACAWN		 PBM
Narasimhan et al.(2015)
pTH8998		 (Direct) (Direct)
mab-3
M07546_2.00		 Caenorhabditis elegans
AATGTTGCSWWNT
ANWWSGCAACATT		 EMSA
Mathelier et al.(2014)
MA0262.1		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.845 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00653_2.00 DM 24 69
M00653_2.00 DM 90 137

DNA Binding Domains

Protein ID Domain From To Sequence
Y53C12B.5a DM 24 69
Y53C12B.5a DM 90 137

Links

Other DM family TFs
Other Caenorhabditis elegans TFs

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10 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action