GRHL1 (Homo sapiens)
Grainyhead

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF04516 (CP2) IPR007604 ENSG00000134317 T199007_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
GRHL1
M03071_2.00		 Homo sapiens
RACYKGWHNDWCMGGTT
AACCKGWHNDWCMRGTY		 SELEX
Jolma et al.(2013)
GRHL1_1		 (Direct) (Direct)
GRHL1
M03072_2.00		 Homo sapiens
DAACCGGTTH
DAACCGGTTH		 SELEX
Jolma et al.(2013)
GRHL1_2		 (Direct) (Direct)
GRHL1
M03073_2.00		 Homo sapiens
HWAACCGGTTTD
HAAACCGGTTWD		 SELEX
Jolma et al.(2013)
GRHL1_3		 (Direct) (Direct)
GRHL1
M04887_2.00		 Homo sapiens
DAACCGGTTH
DAACCGGTTH		 SELEX
Yin et al.(2017)
GRHL1_eDBD_HT-SELEX		 (Direct) (Direct)
GRHL1
M04888_2.00		 Homo sapiens
DAACMKGTTH
DAACMKGTTH		 SELEX
Yin et al.(2017)
GRHL1_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
GRHL2
M08129_2.00 		Homo sapiens
NNNAACTGGTTTNNN
NNNAAACCAGTTNNN		 ChIP-seq
Mathelier et al.(2014)
MA1105.1 		0.723 0.723
GRHL2
M09125_2.00 		Homo sapiens
AACYDGYYBDDC
GHHVRRCHRGTT		 Misc
Kulakovskiy et al.(2013)
GRHL2_HUMAN.H11MO.0.A 		0.723 0.723
Grhl2
M09126_2.00 		Mus musculus
RDCCDGTYYKDC
GHMRRACHGGHY		 Misc
Kulakovskiy et al.(2013)
GRHL2_MOUSE.H11MO.0.A 		0.723 0.723
GRHL2
M09558_2.00 		Homo sapiens
NRAACHDGHHDDDCHDGTTY
RAACHDGHHHDDCHDGTTYN		 Misc
Heinz et al.(2010)
HBE-GRHL2_GSE46194 		0.723 0.723
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000324693 Grainyhead 230 442
ENSP00000384209 Grainyhead 34 253
ENSP00000418275 Grainyhead 230 442

Links

Other Grainyhead family TFs
Other Homo sapiens TFs

109 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
C1orf35 Otolemur garnettii ENSOGAG00000010978 I
RGD1304587 Rattus norvegicus ENSRNOG00000002944 I
OMERI10G00680 Oryza meridionalis OMERI10G00680 I
Traes_4BL_011308A76 Triticum aestivum Traes_4BL_011308A76 I
GLYMA07G12160 Glycine max GLYMA07G12160 N
GLYMA09G30040 Glycine max GLYMA09G30040 N
GLYMA09G30050 Glycine max GLYMA09G30050 N
VIT_17s0000g01860 Vitis vinifera VIT_17s0000g01860 N
Ca_22170 Cicer arietinum Ca_22170 N
LjSGA_029364.2 Lotus japonicus LjSGA_029364.2 N