CDX2 (Homo sapiens)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSG00000165556 T209886_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
CDX2
M03196_2.00		 Homo sapiens
KTTTATKRB
VYMATAAAM		 SELEX
Jolma et al.(2013)
CDX2_1		 (Direct) (Direct)
CDX2
M05248_2.00		 Homo sapiens
NDTWAYRRYN
NRYYRTWAHN		 SELEX
Yin et al.(2017)
CDX2_eDBD_HT-SELEX_1		 (Direct) (Direct)
CDX2
M05249_2.00		 Homo sapiens
NDWWATKRB
VYMATWWHN		 SELEX
Yin et al.(2017)
CDX2_eDBD_HT-SELEX_2		 (Direct) (Direct)
CDX2
M05250_2.00		 Homo sapiens
NRTCGTAWHBNN
NNVDWTACGAYN		 SELEX
Yin et al.(2017)
CDX2_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)
CDX2
M08131_2.00		 Homo sapiens
YTTTATKRCHB
VDGYMATAAAR		 ChIP-seq
Mathelier et al.(2014)
MA0465.1		 (Direct) (Direct)
CDX2
M09152_2.00		 Homo sapiens
DTTBATKGCHNB
VNDGCMATVAAH		 Misc
Kulakovskiy et al.(2013)
CDX2_HUMAN.H11MO.0.A		 (Direct) (Direct)
CDX2
M10723_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CDX2_Q5_01		 (Direct) (Direct)
CDX2
M10724_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CDX2_Q5_02		 (Direct) (Direct)
CDX2
M10725_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CDX2_Q5		 (Direct) (Direct)
CDX2
M10726_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CDX2_Q6		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Cdx2
M00447_2.00 		Mus musculus
NWWAYDRNN
NNYHRTWWN		 PBM
Berger et al.(2008)
Cdx2_4272 		0.862 0.965
Cdx2
M09193_2.00 		Mus musculus
BTTTATKRCYBY
RVRGYMATAAAV		 Misc
Kulakovskiy et al.(2013)
CDX2_MOUSE.H11MO.0.A 		0.862 0.965
Cdx2
M09572_2.00 		Mus musculus
NTTTTATKRC
GYMATAAAAN		 Misc
Heinz et al.(2010)
mES-Cdx2_GSE14586 		0.862 0.965
CDX1
M10761_2.00 		Gallus gallus
BDBWAAK
MTTWVHV		 Transfac
Matys et al.(2006)
V$CDXA_01 		0.855 0.965
CDX1
M10762_2.00 		Gallus gallus
WWWWMYR
YRKWAWW		 Transfac
Matys et al.(2006)
V$CDXA_02 		0.855 0.965
Cdx1
M00427_2.00 		Mus musculus
NWWATDRNN
NNYHATWWN		 PBM
Berger et al.(2008)
Cdx1_2245 		0.855 0.947
CDX1
M03115_2.00 		Homo sapiens
NTTTATKRB
VYMATAAAN		 SELEX
Jolma et al.(2013)
CDX1_1 		0.855 0.947
CDX1
M05018_2.00 		Homo sapiens
VKTTTATKRCN
NGYMATAAAMB		 SELEX
Yin et al.(2017)
CDX1_eDBD_HT-SELEX 		0.855 0.947
CDX1
M09140_2.00 		Homo sapiens
HCWTAAAD
HTTTAWGD		 Misc
Kulakovskiy et al.(2013)
CDX1_HUMAN.H11MO.0.C 		0.855 0.947
Cdx1
M09186_2.00 		Mus musculus
HCWTAAAD
HTTTAWGD		 Misc
Kulakovskiy et al.(2013)
CDX1_MOUSE.H11MO.0.C 		0.855 0.947
CDX1
M10670_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CDX1_Q4 		0.855 0.947
CDX1
M10671_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CDX1_Q5 		0.855 0.947
CDX1
M05019_2.00 		Homo sapiens
NGTCGTAAAWB
VWTTTACGACN		 SELEX
Yin et al.(2017)
CDX1_eDBD_Methyl-HT-SELEX 		0.855 0.947
cad
M03780_2.00 		Drosophila melanogaster
NKTTTATKRCHB
VDGYMATAAAMN		 SELEX
Nitta et al.(2015)
cad_1 		0.851 0.877
cad
M03781_2.00 		Drosophila melanogaster
NDTTTATKRCHN
NDGYMATAAAHN		 SELEX
Nitta et al.(2015)
cad_2 		0.851 0.877
cad
M03782_2.00 		Drosophila melanogaster
NDTTTATKRCNB
VNGYMATAAAHN		 SELEX
Nitta et al.(2015)
cad_3 		0.851 0.877
cad
M03783_2.00 		Drosophila melanogaster
NNTTTAYGRYNN
NNRYCRTAAANN		 SELEX
Nitta et al.(2015)
cad_4 		0.851 0.877
cad
M06223_2.00 		Drosophila melanogaster
HTTWATTR
YAATWAAD		 B1H
Zhu et al.(2011)
Cad_Cell_FBgn0000251 		0.851 0.877
cad
M06224_2.00 		Drosophila melanogaster
RBYVDAAMV
BKTTHBRVY		 B1H
Zhu et al.(2011)
cad_FlyReg_FBgn0000251 		0.851 0.877
cad
M06225_2.00 		Drosophila melanogaster
NTTWATKR
YMATWAAN		 B1H
Zhu et al.(2011)
Cad_SOLEXA_FBgn0000251 		0.851 0.877
cad
M08420_2.00 		Drosophila melanogaster
DTTTTATKRYY
RRYMATAAAAH		 ChIP-chip
Mathelier et al.(2014)
MA0216.2 		0.851 0.877
cad
M09580_2.00 		Drosophila melanogaster
DTTTAYGRYN
NRYCRTAAAH		 Misc
Heinz et al.(2010)
Drosophila-Embryos_modEncode 		0.851 0.877
cad
M09674_2.00 		Drosophila melanogaster
HTTTATKRBY
RVYMATAAAD		 Misc
Kulakovskiy et al.(2009)
cad 		0.851 0.877
cad
M10783_2.00 		Drosophila melanogaster Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
I$CAD_Q6 		0.851 0.877
Q70LF3_ARTSF
M02211_2.00 		Artemia franciscana
BTAATTAB
VTAATTAV		 PBM
Weirauch et al.(2014)
pTH5553 		0.834 0.895
Cdx4
M09197_2.00 		Mus musculus
WGATTTATDRBH
DVYHATAAATCW		 Misc
Kulakovskiy et al.(2013)
CDX4_MOUSE.H11MO.0.A 		0.819 0.895
CDX4
M05129_2.00 		Homo sapiens
VKTTTATKRCH
DGYMATAAAMB		 SELEX
Yin et al.(2017)
CDX4_FL_HT-SELEX 		0.819 0.877
CDX4
M05130_2.00 		Homo sapiens
BGTCGTAAAHN
NDTTTACGACV		 SELEX
Yin et al.(2017)
CDX4_FL_Methyl-HT-SELEX_1 		0.819 0.877
CDX4
M05131_2.00 		Homo sapiens
VKTTTATKGCN
NGCMATAAAMB		 SELEX
Yin et al.(2017)
CDX4_FL_Methyl-HT-SELEX_2 		0.819 0.877
pal-1
M02183_2.00 		Caenorhabditis elegans
GYAATWAA
TTWATTRC		 PBM
Weirauch et al.(2014)
pTH6016 		0.650 0.684
Q9GP48_9TURB
M02217_2.00 		Discocelis tigrina
DTAATTAB
VTAATTAH		 PBM
Weirauch et al.(2014)
pTH6515 		0.641 0.702
Q24782_9CNID
M02206_2.00 		Eleutheria dichotoma
TTAATTAA
TTAATTAA		 PBM
Weirauch et al.(2014)
pTH5486 		0.613 0.561
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000370408 Homeodomain 187 243

Links

Other Homeodomain family TFs
Other Homo sapiens TFs

346 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSORLG00000000044 Oryzias latipes ENSORLG00000000044 D 0.000
lcorl Xenopus tropicalis XB-GENE-995017 D 0.000
ENSORLG00000007805 Oryzias latipes ENSORLG00000007805 D 0.000
ENSACAG00000012432 Anolis carolinensis ENSACAG00000012432 D 0.000
ENSMGAG00000009953 Meleagris gallopavo ENSMGAG00000009953 D 0.000
ENSGACG00000007469 Gasterosteus aculeatus ENSGACG00000007469 D 0.000
LCORL Homo sapiens ENSG00000178177 D 0.000
LCORL Choloepus hoffmanni ENSCHOG00000006922 D 0.000
ENSTTRG00000009856 Tursiops truncatus ENSTTRG00000009856 I 0.000
ENSVPAG00000007583 Vicugna pacos ENSVPAG00000007583 I 0.000
ENSTRUG00000008704 Takifugu rubripes ENSTRUG00000008704 I 0.000
lcor Takifugu rubripes ENSTRUG00000006194 I 0.000
lcor Tetraodon nigroviridis ENSTNIG00000003614 I 0.000
ENSTGUG00000009834 Taeniopygia guttata ENSTGUG00000009834 I 0.000
LCORL Tupaia belangeri ENSTBEG00000012926 I 0.000
ENSSTOG00000010808 Ictidomys tridecemlineatus ENSSTOG00000010808 I 0.000
ENSSSCG00000010511 Sus scrofa ENSSSCG00000010511 I 0.000
ENSSHAG00000018667 Sarcophilus harrisii ENSSHAG00000018667 I 0.000
ENSSARG00000008230 Sorex araneus ENSSARG00000008230 I 0.000
Lcor Rattus norvegicus ENSRNOG00000042679 I 0.000
ENSPVAG00000003364 Pteropus vampyrus ENSPVAG00000003364 I 0.000
LCOR Pan troglodytes ENSPTRG00000002800 I 0.000
ENSPSIG00000009179 Pelodiscus sinensis ENSPSIG00000009179 I 0.000
ENSPMAG00000003112 Petromyzon marinus ENSPMAG00000003112 I 0.000
ENSBTAP00000005261-D1 Bos grunniens ENSBTAP00000005261-D1 I 0.000
ENSAMEG00000000186 Ailuropoda melanoleuca ENSAMEG00000000186 I 0.000
Tal_R010723 Tyto alba Tal_R010723 I 0.000
Pvit_17823 Pogona vitticeps Pvit_17823 I 0.000
Ogr16502 Ophisaurus gracilis Ogr16502 I 0.000
Myotis_brandtii_LCORL_10024398 Myotis brandtii Myotis_brandtii_LCORL_10024398 I 0.000
Myotis_brandtii_LCOR_10025723 Myotis brandtii Myotis_brandtii_LCOR_10025723 I 0.000
Gfo_R002325 Geospiza fortis Gfo_R002325 I 0.000
ENSP00000360138 Macaca fascicularis ENSP00000360138 I 0.000
ENSPFOG00000009902 Poecilia formosa ENSPFOG00000009902 I 0.000
Cmyd_10003742 Chelonia mydas Cmyd_10003742 I 0.000
Brh_R001506 Buceros rhinoceros Brh_R001506 I 0.000
Alligator_sinensis_CCG020164.1 Alligator sinensis Alligator_sinensis_CCG020164.1 I 0.000
Afo_R002709 Aptenodytes forsteri Afo_R002709 I 0.000
Aan_R012556 Calypte anna Aan_R012556 I 0.000
ENSXMAG00000005637 Xiphophorus maculatus ENSXMAG00000005637 I 0.000
ENSXMAG00000002515 Xiphophorus maculatus ENSXMAG00000002515 I 0.000
ENSFCAG00000028121 Felis catus ENSFCAG00000028121 I 0.000
ENSLAFG00000014271 Loxodonta africana ENSLAFG00000014271 I 0.000
ENSLACG00000001265 Latimeria chalumnae ENSLACG00000001265 I 0.000
ENSGMOG00000018278 Gadus morhua ENSGMOG00000018278 I 0.000
ENSGGOG00000026110 Gorilla gorilla ENSGGOG00000026110 I 0.000
ENSGALG00000023649 Gallus gallus ENSGALG00000023649 I 0.000
ENSCAFG00000008905 Canis familiaris ENSCAFG00000008905 I 0.000
LCOR Homo sapiens ENSG00000196233 I 0.000
ENSCHOG00000001981 Choloepus hoffmanni ENSCHOG00000001981 I 0.000
ENSLOCG00000012823 Lepisosteus oculatus ENSLOCG00000012823 I 0.000
ENSFALG00000008484 Ficedula albicollis ENSFALG00000008484 I 0.000
ENSETEG00000015066 Echinops telfairi ENSETEG00000015066 I 0.000
ENSECAG00000013517 Equus caballus ENSECAG00000013517 I 0.000
lcor Danio rerio ENSDARG00000100908 I 0.000
ENSCSAG00000006043 Chlorocebus sabaeus ENSCSAG00000006043 I 0.000
ENSCPOG00000005739 Cavia porcellus ENSCPOG00000005739 I 0.000
ENSCJAG00000016484 Callithrix jacchus ENSCJAG00000016484 I 0.000
ENSPFOG00000013017 Poecilia formosa ENSPFOG00000013017 I 0.000
ENSBTAG00000004029 Bos taurus ENSBTAG00000004029 I 0.000
ENSMICG00000007572 Microcebus murinus ENSMICG00000007572 I 0.000
ENSMLUG00000000494 Myotis lucifugus ENSMLUG00000000494 I 0.000
ENSMMUG00000010425 Macaca mulatta ENSMMUG00000010425 I 0.000
ENSMODG00000004531 Monodelphis domestica ENSMODG00000004531 I 0.000
Lcor Mus musculus ENSMUSG00000025019 I 0.000
ENSNLEG00000013648 Nomascus leucogenys ENSNLEG00000013648 I 0.000
ENSOARG00000008725 Ovis aries ENSOARG00000008725 I 0.000
ENSOGAG00000008137 Otolemur garnettii ENSOGAG00000008137 I 0.000
ENSONIG00000000255 Oreochromis niloticus ENSONIG00000000255 I 0.000
ENSONIG00000018331 Oreochromis niloticus ENSONIG00000018331 I 0.000
ENSOPRG00000014745 Ochotona princeps ENSOPRG00000014745 I 0.000
ENSAPLG00000003032 Anas platyrhynchos ENSAPLG00000003032 I 0.000
ENSAMXG00000021599 Astyanax mexicanus ENSAMXG00000021599 I 0.000
ENSPCAG00000007084 Procavia capensis ENSPCAG00000007084 I 0.000