nkx2.4b (Tetraodon nigroviridis)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSTNIG00000010713 T216490_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
scro
M03854_2.00 		Drosophila melanogaster
NNBRMGTGB
VCACKYVNN		 SELEX
Nitta et al.(2015)
scro_1 		0.846 0.895
Nkx2-1
M00385_2.00 		Mus musculus
NNRAGDRN
NYHCTYNN		 PBM
Berger et al.(2008)
Titf1_1722 		0.839 0.912
Nkx2-4
M00514_2.00 		Mus musculus
NNRAGDRBNN
NNVYHCTYNN		 PBM
Berger et al.(2008)
Nkx2-4_3074 		0.839 0.912
NKX2-1
M09146_2.00 		Homo sapiens
BTKGAGWGBN
NVCWCTCMAV		 Misc
Kulakovskiy et al.(2013)
NKX21_HUMAN.H11MO.0.A 		0.839 0.912
Nkx2-1
M09171_2.00 		Mus musculus
NBTKGAGWGB
VCWCTCMAVN		 Misc
Kulakovskiy et al.(2013)
NKX21_MOUSE.H11MO.0.A 		0.839 0.912
Nkx2-1
M09563_2.00 		Mus musculus
BTBRAGWGBH
DVCWCTYVAV		 Misc
Heinz et al.(2010)
LungAC-Nkx2.1_GSE43252 		0.839 0.912
NKX2-1
M10694_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TITF1_Q3 		0.839 0.912
NKX2-1
M10695_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TTF1_Q5_01 		0.839 0.912
NKX2-1
M10696_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TTF1_Q5 		0.839 0.912
NKX2-1
M10697_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TTF1_Q6 		0.839 0.912
ceh-24
M02181_2.00 		Caenorhabditis elegans
NNRAKWRNN
NNYWMTYNN		 PBM
Weirauch et al.(2014)
pTH6327 		0.837 0.842
Nkx2-9
M00520_2.00 		Mus musculus
NNNRAGDRBN
NVYHCTYNNN		 PBM
Berger et al.(2008)
Nkx2-9_3082 		0.803 0.807
Nkx2-9
M00800_2.00 		Mus musculus
NNRAGDRBNN
NNVYHCTYNN		 PBM
Weirauch et al.(2013)
pTH2842 		0.803 0.807
Nkx2-9
M09215_2.00 		Mus musculus
BTCAAGKRB
VYMCTTGAV		 Misc
Kulakovskiy et al.(2013)
NKX28_MOUSE.H11MO.0.C 		0.803 0.807
Nkx2-2
M00438_2.00 		Mus musculus
NNNRAGDRN
NYHCTYNNN		 PBM
Berger et al.(2008)
Nkx2-2_2823 		0.794 0.842
Nkx2-2
M09190_2.00 		Mus musculus
NTBRAGWGBBN
NVVCWCTYVAN		 Misc
Kulakovskiy et al.(2013)
NKX22_MOUSE.H11MO.0.A 		0.794 0.842
NKX2-2
M10681_2.00 		Homo sapiens
WTAAGTRBTT
AAVYACTTAW		 Transfac
Matys et al.(2006)
V$NKX22_01 		0.794 0.842
NKX2-2
M10682_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NKX2B_Q3_01 		0.794 0.842
NKX2-2
M10683_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NKX2B_Q3 		0.794 0.842
vnd
M06551_2.00 		Drosophila melanogaster
WYTCAAGTR
YACTTGARW		 B1H
Mathelier et al.(2014)
MA0253.1 		0.794 0.825
vnd
M06377_2.00 		Drosophila melanogaster
WYTCAAGTR
YACTTGARW		 B1H
Zhu et al.(2011)
Vnd_Cell_FBgn0003986 		0.794 0.825
vnd
M06378_2.00 		Drosophila melanogaster
KYTSAAGWGY
RCWCTTSARM		 B1H
Zhu et al.(2011)
vnd_FlyReg_FBgn0003986 		0.794 0.825
vnd
M06379_2.00 		Drosophila melanogaster
BTBAAGTR
YACTTVAV		 B1H
Zhu et al.(2011)
Vnd_SOLEXA_FBgn0003986 		0.794 0.825
vnd
M09683_2.00 		Drosophila melanogaster
TCAAGTGB
VCACTTGA		 Misc
Kulakovskiy et al.(2009)
vnd 		0.794 0.825
NKX2-5
M00323_2.00 		Homo sapiens
NWYAAGTGSNN
NNSCACTTRWN		 PBM
Barrera et al.(2016)
NKX2-5_REF 		0.787 0.772
Nkx2-5
M00404_2.00 		Mus musculus
NNNRAGDRBN
NVYHCTYNNN		 PBM
Berger et al.(2008)
Nkx2-5_3436 		0.787 0.772
NKX2-5
M05346_2.00 		Homo sapiens
BHYAAGTGBN
NVCACTTRDV		 SELEX
Yin et al.(2017)
NKX2-5_FL_HT-SELEX 		0.787 0.772
Nkx2-5
M02686_2.00 		Mus musculus
WTAAKWK
MWMTTAW		 SELEX
Mathelier et al.(2014)
MA0063.1 		0.787 0.772
Nkx2-5
M08136_2.00 		Mus musculus
SYTGAGWGSYH
DRSCWCTCARS		 ChIP-seq
Mathelier et al.(2014)
MA0503.1 		0.787 0.772
NKX2-5
M09163_2.00 		Homo sapiens
BKRAGWGV
BCWCTYMV		 Misc
Kulakovskiy et al.(2013)
NKX25_HUMAN.H11MO.0.B 		0.787 0.772
Nkx2-5
M09177_2.00 		Mus musculus
NBYBRAGTGS
SCACTYVRVN		 Misc
Kulakovskiy et al.(2013)
NKX25_MOUSE.H11MO.0.A 		0.787 0.772
Nkx2-5
M09567_2.00 		Mus musculus
HBRAGWGBNN
NNVCWCTYVD		 Misc
Heinz et al.(2010)
HL1-Nkx2.5.biotin_GSE21529 		0.787 0.772
NKX2-5
M10742_2.00 		Homo sapiens
TYAAGTG
CACTTRA		 Transfac
Matys et al.(2006)
V$NKX25_01 		0.787 0.772
NKX2-5
M10743_2.00 		Homo sapiens
CWTAATTV
BAATTAWG		 Transfac
Matys et al.(2006)
V$NKX25_02 		0.787 0.772
NKX2-5
M10744_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NKX25_Q5 		0.787 0.772
NKX2-5
M10745_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NKX25_Q6 		0.787 0.772
NKX2-5
M00321_2.00 		Homo sapiens
HNAAGTRBNN
NNVYACTTND		 PBM
Barrera et al.(2016)
NKX2-5_R161P 		0.787 0.772
NKX2-5
M05347_2.00 		Homo sapiens
BTYAAGTGGN
NCCACTTRAV		 SELEX
Yin et al.(2017)
NKX2-5_FL_Methyl-HT-SELEX_1 		0.787 0.772
NKX2-5
M05348_2.00 		Homo sapiens
BTYAACGAB
VTCGTTRAV		 SELEX
Yin et al.(2017)
NKX2-5_FL_Methyl-HT-SELEX_2 		0.787 0.772
NKX2-5
M00322_2.00 		Homo sapiens
NNNRNNN
NNNYNNN		 PBM
Barrera et al.(2016)
NKX2-5_R190C 		0.787 0.754
NKX2-5
M00324_2.00 		Homo sapiens
NHNNNNN
NNNNNDN		 PBM
Barrera et al.(2016)
NKX2-5_T178M 		0.787 0.754
Nkx2-3
M00497_2.00 		Mus musculus
NNRAGDRNN
NNYHCTYNN		 PBM
Berger et al.(2008)
Nkx2-3_3435 		0.785 0.789
NKX2-3
M05042_2.00 		Homo sapiens
NNBAAGTGBN
NVCACTTVNN		 SELEX
Yin et al.(2017)
NKX2-3_eDBD_HT-SELEX 		0.785 0.789
NKX2-3
M05045_2.00 		Homo sapiens
BNBAAGTGBN
NVCACTTVNV		 SELEX
Yin et al.(2017)
NKX2-3_FL_HT-SELEX 		0.785 0.789
NKX2-3
M05043_2.00 		Homo sapiens
BNBAAGTGBN
NVCACTTVNV		 SELEX
Yin et al.(2017)
NKX2-3_eDBD_Methyl-HT-SELEX_1 		0.785 0.789
NKX2-3
M05044_2.00 		Homo sapiens
SDYAACGHB
VDCGTTRHS		 SELEX
Yin et al.(2017)
NKX2-3_eDBD_Methyl-HT-SELEX_2 		0.785 0.789
NKX2-3
M05046_2.00 		Homo sapiens
BNBAAGTGBN
NVCACTTVNV		 SELEX
Yin et al.(2017)
NKX2-3_FL_Methyl-HT-SELEX_1 		0.785 0.789
NKX2-3
M05047_2.00 		Homo sapiens
SWYAACSHB
VDSGTTRWS		 SELEX
Yin et al.(2017)
NKX2-3_FL_Methyl-HT-SELEX_2 		0.785 0.789
ceh-28
M08210_2.00 		Caenorhabditis elegans
AATCGATW
WATCGATT		 ChIP-seq
Contrino et al.(2012)
Mw138 		0.781 0.667
NKX2-8
M00302_2.00 		Homo sapiens
NNRAGDRB
VYHCTYNN		 PBM
Barrera et al.(2016)
NKX2-8_REF 		0.771 0.789
NKX2-8
M05149_2.00 		Homo sapiens
BTSRAGTGBN
NVCACTYSAV		 SELEX
Yin et al.(2017)
NKX2-8_FL_HT-SELEX 		0.771 0.789
NKX2-8
M09145_2.00 		Homo sapiens
BTCAAGKRB
VYMCTTGAV		 Misc
Kulakovskiy et al.(2013)
NKX28_HUMAN.H11MO.0.C 		0.771 0.789
NKX2-8
M00301_2.00 		Homo sapiens
NNRAKDRB
VYHMTYNN		 PBM
Barrera et al.(2016)
NKX2-8_A94T 		0.771 0.789
NKX2-8
M05150_2.00 		Homo sapiens
GCARTAACGACATC
GATGTCGTTAYTGC		 SELEX
Yin et al.(2017)
NKX2-8_FL_Methyl-HT-SELEX_1 		0.771 0.789
NKX2-8
M05151_2.00 		Homo sapiens
BTSAAGTGBN
NVCACTTSAV		 SELEX
Yin et al.(2017)
NKX2-8_FL_Methyl-HT-SELEX_2 		0.771 0.789
NKX2-8
M05152_2.00 		Homo sapiens
BTBAACGAB
VTCGTTVAV		 SELEX
Yin et al.(2017)
NKX2-8_FL_Methyl-HT-SELEX_3 		0.771 0.789
tin
M00559_2.00 		Drosophila melanogaster
NWYAAGTGGNN
NNCCACTTRWN		 PBM
Busser et al.(2012a)
Tin 		0.771 0.632
tin
M03809_2.00 		Drosophila melanogaster
BTYAAGTGSN
NSCACTTRAV		 SELEX
Nitta et al.(2015)
tin_1 		0.771 0.632
tin
M06284_2.00 		Drosophila melanogaster
BTYAAGTG
CACTTRAV		 B1H
Zhu et al.(2011)
Tin_Cell_FBgn0004110 		0.771 0.632
tin
M06285_2.00 		Drosophila melanogaster
BCTCAAGTGSVN
NBSCACTTGAGV		 B1H
Zhu et al.(2011)
tin_FlyReg_FBgn0004110 		0.771 0.632
tin
M06286_2.00 		Drosophila melanogaster
BWYAAGTR
YACTTRWV		 B1H
Zhu et al.(2011)
Tin_SOLEXA_FBgn0004110 		0.771 0.632
tin
M08421_2.00 		Drosophila melanogaster
DBTCRAGTGS
SCACTYGAVH		 ChIP-chip
Mathelier et al.(2014)
MA0247.2 		0.771 0.632
Nkx2-6
M00496_2.00 		Mus musculus
HYAAGTRBNN
NNVYACTTRD		 PBM
Berger et al.(2008)
Nkx2-6_3437 		0.763 0.737
ceh-22
M00376_2.00 		Caenorhabditis elegans
WBRAGTRBNN
NNVYACTYVW		 PBM
Berger et al.(2006)
Ceh-22 		0.761 0.772
NKX2-5
M00320_2.00 		Homo sapiens
NHBAAKWRN
NYWMTTVDN		 PBM
Barrera et al.(2016)
NKX2-5_K183E 		0.754 0.754
Q24782_9CNID
M02206_2.00 		Eleutheria dichotoma
TTAATTAA
TTAATTAA		 PBM
Weirauch et al.(2014)
pTH5486 		0.612 0.491
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSTNIP00000013631 Homeodomain 160 216

Links

Other Homeodomain family TFs
Other Tetraodon nigroviridis TFs

832 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
Traes_3DL_6A5CA5C37 Triticum aestivum Traes_3DL_6A5CA5C37 N
OS01G0517800 Oryza sativa OS01G0517800 N
OS01G0518000 Oryza sativa OS01G0518000 N
OS08G0560300 Oryza sativa OS08G0560300 N
PGSC0003DMG400008598 Solanum tuberosum PGSC0003DMG400008598 N
Sb07g024020 Sorghum bicolor Sb07g024020 N
Sb08g005380 Sorghum bicolor Sb08g005380 N
Si004357m.g Setaria italica Si004357m.g N
Si004634m.g Setaria italica Si004634m.g N
Si004809m.g Setaria italica Si004809m.g N
Solyc10g085800.1 Solanum lycopersicum Solyc10g085800.1 N
Traes_3AL_970EF6E45 Triticum aestivum Traes_3AL_970EF6E45 N
Traes_3AL_CF608F443 Triticum aestivum Traes_3AL_CF608F443 N
TRAES3BF035900070CFD_g Triticum aestivum TRAES3BF035900070CFD_g N
TRAES3BF035900140CFD_g Triticum aestivum TRAES3BF035900140CFD_g N
TRAES3BF035900190CFD_g Triticum aestivum TRAES3BF035900190CFD_g N
ORUFI08G26100 Oryza rufipogon ORUFI08G26100 N
Traes_3DL_96F825D26 Triticum aestivum Traes_3DL_96F825D26 N
Traes_7AS_9EA289C71 Triticum aestivum Traes_7AS_9EA289C71 N
Traes_7DS_620E0D488 Triticum aestivum Traes_7DS_620E0D488 N
TRIUR3_09966 Triticum urartu TRIUR3_09966 N
TRIUR3_27842 Triticum urartu TRIUR3_27842 N
fgenesh1_pg.scaffold_102000043 Physcomitrella patens fgenesh1_pg.scaffold_102000043 N
Ciclev10012712m.g Citrus clementina Ciclev10012712m.g N
orange1.1g027730m.g Citrus sinensis orange1.1g027730m.g N
Pavir.Ea01651 Panicum virgatum Pavir.Ea01651 N
Pavir.Eb01352 Panicum virgatum Pavir.Eb01352 N
Pavir.Eb02108 Panicum virgatum Pavir.Eb02108 N
Pavir.Fa00017 Panicum virgatum Pavir.Fa00017 N
Pavir.Fb02226 Panicum virgatum Pavir.Fb02226 N
Pavir.J13246 Panicum virgatum Pavir.J13246 N
OBART08G23610 Oryza barthii OBART08G23610 N
BGIOSGA001528 Oryza indica BGIOSGA001528 N
BGIOSGA026486 Oryza indica BGIOSGA026486 N
BRADI3G43000 Brachypodium distachyon BRADI3G43000 N
F775_22386 Aegilops tauschii F775_22386 N
F775_30314 Aegilops tauschii F775_30314 N
GRMZM2G006585 Zea mays GRMZM2G006585 N
GRMZM2G171934 Zea mays GRMZM2G171934 N
LPERR01G15600 Leersia perrieri LPERR01G15600 N
LPERR08G20370 Leersia perrieri LPERR08G20370 N
MLOC_23439 Hordeum vulgare MLOC_23439 N
MLOC_26846 Hordeum vulgare MLOC_26846 N
OB01G27340 Oryza brachyantha OB01G27340 N
OB08G30470 Oryza brachyantha OB08G30470 N
OBART01G17820 Oryza barthii OBART01G17820 N
OBART01G17850 Oryza barthii OBART01G17850 N
BGIOSGA001527 Oryza indica BGIOSGA001527 N
OGLUM01G21100 Oryza glumaepatula OGLUM01G21100 N
OGLUM08G25080 Oryza glumaepatula OGLUM08G25080 N
OLONG_020563 Oryza longistaminata OLONG_020563 N
OMERI01G16650 Oryza meridionalis OMERI01G16650 N
OMERI01G16670 Oryza meridionalis OMERI01G16670 N
OMERI08G18450 Oryza meridionalis OMERI08G18450 N
ONIVA08G26670 Oryza nivara ONIVA08G26670 N
OPUNC01G18340 Oryza punctata OPUNC01G18340 N
OPUNC01G18360 Oryza punctata OPUNC01G18360 N
OPUNC08G21610 Oryza punctata OPUNC08G21610 N
ORGLA01G0145800 Oryza glaberrima ORGLA01G0145800 N
ORGLA08G0190300 Oryza glaberrima ORGLA08G0190300 N
ORGLA11G0065100 Oryza glaberrima ORGLA11G0065100 N
ORGLA11G0204800 Oryza glaberrima ORGLA11G0204800 N