IRF4 (Choloepus hoffmanni)
IRF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00605 (IRF) IPR001346 ENSCHOG00000012417 T243967_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Irf4
M00175_2.00 		Mus musculus
NNNYGAWASN
NSTWTCRNNN		 PBM
Badis et al.(2009)
Irf4_3476 		1.000 1.000
IRF4
M03334_2.00 		Homo sapiens
HCGAAACCGAAACYW
WRGTTTCGGTTTCGD		 SELEX
Jolma et al.(2013)
IRF4_1 		1.000 1.000
IRF4
M05539_2.00 		Homo sapiens
NYGAAACYGAAACYN
NRGTTTCRGTTTCRN		 SELEX
Yin et al.(2017)
IRF4_FL_HT-SELEX 		1.000 1.000
IRF4
M07978_2.00 		Homo sapiens
DNDVNNGWWVTGAVWVWN
NWBWBTCABWWCNNBHNH		 ChIP-seq
Gerstein et al.(2012)
GM12878_IRF4_HudsonAlpha 		1.000 1.000
IRF4
M09235_2.00 		Homo sapiens
NDWDRRGGAASTGARAVH
DBTYTCASTTCCYYHWHN		 Misc
Kulakovskiy et al.(2013)
IRF4_HUMAN.H11MO.0.A 		1.000 1.000
Irf4
M09243_2.00 		Mus musculus
NDAWVVRGAASTGARAVH
DBTYTCASTTCYBBWTHN		 Misc
Kulakovskiy et al.(2013)
IRF4_MOUSE.H11MO.0.A 		1.000 1.000
IRF4
M09595_2.00 		Homo sapiens
HNYGAAASYD
HRSTTTCRND		 Misc
Heinz et al.(2010)
GM12878-IRF4_GSE32465 		1.000 1.000
IRF4
M10885_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF4_07 		1.000 1.000
IRF4
M10886_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF4_08 		1.000 1.000
IRF4
M10887_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF4_Q5_01 		1.000 1.000
IRF4
M10888_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF4_Q5 		1.000 1.000
IRF4
M10889_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF4_Q6 		1.000 1.000
IRF4
M05540_2.00 		Homo sapiens
NYGAAASYGAWASHN
NDSTWTCRSTTTCRN		 SELEX
Yin et al.(2017)
IRF4_FL_Methyl-HT-SELEX 		1.000 1.000
IRF8
M03335_2.00 		Homo sapiens
HCGAAACYGAAACY
RGTTTCRGTTTCGD		 SELEX
Jolma et al.(2013)
IRF8_1 		0.804 0.804
IRF8
M03336_2.00 		Homo sapiens
HCGAAACCGAAACT
AGTTTCGGTTTCGD		 SELEX
Jolma et al.(2013)
IRF8_2 		0.804 0.804
IRF8
M05541_2.00 		Homo sapiens
NYGAAASYGAAASHN
NDSTTTCRSTTTCRN		 SELEX
Yin et al.(2017)
IRF8_eDBD_HT-SELEX 		0.804 0.804
IRF8
M05543_2.00 		Homo sapiens
NCGAAACYGAAACYN
NRGTTTCRGTTTCGN		 SELEX
Yin et al.(2017)
IRF8_FL_HT-SELEX 		0.804 0.804
IRF8
M09236_2.00 		Homo sapiens
NDDDRRGGAASTGAAASYNN
NNRSTTTCASTTCCYYHHHN		 Misc
Kulakovskiy et al.(2013)
IRF8_HUMAN.H11MO.0.B 		0.804 0.804
Irf8
M09246_2.00 		Mus musculus
NDDDRRGGAASTGAAASYNN
NNRSTTTCASTTCCYYHHHN		 Misc
Kulakovskiy et al.(2013)
IRF8_MOUSE.H11MO.0.A 		0.804 0.804
IRF8
M10890_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ICSBP_Q6 		0.804 0.804
IRF8
M10891_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF8_Q6 		0.804 0.804
IRF8
M05542_2.00 		Homo sapiens
NYGAAASYGAAASYN
NRSTTTCRSTTTCRN		 SELEX
Yin et al.(2017)
IRF8_eDBD_Methyl-HT-SELEX 		0.804 0.804
IRF8
M05544_2.00 		Homo sapiens
NYGAAASYGAAACYD
HRGTTTCRSTTTCRN		 SELEX
Yin et al.(2017)
IRF8_FL_Methyl-HT-SELEX 		0.804 0.804
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSCHOP00000010993 IRF 1 56

Links

Other IRF family TFs
Other Choloepus hoffmanni TFs

62 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
Irf8 Mus musculus ENSMUSG00000041515 D 0.804
Irf4 Mus musculus ENSMUSG00000021356 D 1.000
irf4b Takifugu rubripes ENSTRUG00000002946 I 1.000
IRF8 Procavia capensis ENSPCAG00000004460 I 0.821
ENSPFOG00000015506 Poecilia formosa ENSPFOG00000015506 I 0.875
ENSPFOG00000017639 Poecilia formosa ENSPFOG00000017639 I 0.821
ENSPPYG00000007620 Pongo abelii ENSPPYG00000007620 I 0.804
ENSPSIG00000003518 Pelodiscus sinensis ENSPSIG00000003518 I 0.732
IRF8 Pan troglodytes ENSPTRG00000008435 I 0.804
Irf8 Rattus norvegicus ENSRNOG00000017869 I 0.804
Irf4 Rattus norvegicus ENSRNOG00000061070 I 1.000
ENSSSCG00000022547 Sus scrofa ENSSSCG00000022547 I 0.786
ENSSSCG00000023184 Sus scrofa ENSSSCG00000023184 I 0.804
ENSTGUG00000006609 Taeniopygia guttata ENSTGUG00000006609 I 0.768
irf4a Tetraodon nigroviridis ENSTNIG00000005370 I 0.875
irf8 Tetraodon nigroviridis ENSTNIG00000009283 I 0.786
ENSPANG00000024770 Papio anubis ENSPANG00000024770 I 0.804
irf8 Takifugu rubripes ENSTRUG00000018213 I 0.821
ENSTSYG00000006495 Tarsius syrichta ENSTSYG00000006495 I 1.000
IRF8 Tursiops truncatus ENSTTRG00000016024 I 0.804
ENSXMAG00000017015 Xiphophorus maculatus ENSXMAG00000017015 I 0.875
Aan_R015695 Calypte anna Aan_R015695 I 0.737
Afo_R010468 Aptenodytes forsteri Afo_R010468 I 0.754
ENSP00000268638-D1 Bos grunniens ENSP00000268638-D1 I 0.804
ENSP00000268638 Macaca fascicularis ENSP00000268638 I 0.804
ENSP00000370343 Macaca fascicularis ENSP00000370343 I 0.949
Gfo_R005312 Geospiza fortis Gfo_R005312 I 0.754
Myotis_brandtii_Irf4_10020370 Myotis brandtii Myotis_brandtii_Irf4_10020370 I 0.929
Ogr05775 Ophisaurus gracilis Ogr05775 I 1.000
Tal_R010571 Tyto alba Tal_R010571 I 0.966
irf8.L Xenopus laevis XB-GENE-985949 I 0.804
XP_002934991 Xenopus tropicalis XP_002934991 I 0.804
ENSLOCG00000003532 Lepisosteus oculatus ENSLOCG00000003532 I 0.768
ENSAMXG00000003452 Astyanax mexicanus ENSAMXG00000003452 I 0.821
ENSAMXG00000016370 Astyanax mexicanus ENSAMXG00000016370 I 0.929
IRF8 Bos taurus ENSBTAG00000017824 I 0.804
ENSCAFG00000007099 Canis familiaris ENSCAFG00000007099 I 0.804
ENSCSAG00000003142 Chlorocebus sabaeus ENSCSAG00000003142 I 0.804
irf8 Danio rerio ENSDARG00000056407 I 0.804
IRF8 Equus caballus ENSECAG00000015449 I 0.804
IRF8 Erinaceus europaeus ENSEEUG00000002644 I 0.786
IRF4 Erinaceus europaeus ENSEEUG00000007703 I 0.875
irf4b Gasterosteus aculeatus ENSGACG00000004966 I 0.964
irf4a Gasterosteus aculeatus ENSGACG00000016461 I 0.875
IRF8 Gorilla gorilla ENSGGOG00000028251 I 0.804
ENSLACG00000007228 Latimeria chalumnae ENSLACG00000007228 I 0.750
ENSAMEG00000013647 Ailuropoda melanoleuca ENSAMEG00000013647 I 0.786
ENSMICG00000011721 Microcebus murinus ENSMICG00000011721 I 1.000
IRF8 Macaca mulatta ENSMMUG00000008125 I 0.804
ENSMODG00000019483 Monodelphis domestica ENSMODG00000019483 I 0.714
ENSMPUG00000008641 Mustela putorius furo ENSMPUG00000008641 I 0.804
ENSNLEG00000011429 Nomascus leucogenys ENSNLEG00000011429 I 0.804
IRF8 Ornithorhynchus anatinus ENSOANG00000003741 I 0.804
IRF4 Ornithorhynchus anatinus ENSOANG00000006326 I 0.918
ENSOARG00000011513 Ovis aries ENSOARG00000011513 I 0.804
IRF8 Otolemur garnettii ENSOGAG00000009262 I 0.804
IRF8 Ochotona princeps ENSOPRG00000002139 I 0.804
irf4b Oryzias latipes ENSORLG00000012712 I 0.982
irf4a Oryzias latipes ENSORLG00000017242 I 0.893
irf8 Oryzias latipes ENSORLG00000018216 I 0.821
ENSPANG00000023389 Papio anubis ENSPANG00000023389 I 0.982
Alligator_sinensis_CCG000346.1 Alligator sinensis Alligator_sinensis_CCG000346.1 N 0.768