CIS-BP Database: Catalog of Inferred Sequence Binding Preferences

TF Information

ISL1 *(Choloepus hoffmanni)* Homeodomain
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF00046 (Homeobox)	IPR001356	ENSCHOG00000012504	T207802_2.00	Ensembl (2018-Dec-8)	Link out
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
Isl2 M00458_2.00	Mus musculus	NWDWDNN	NNHWHWN	PBM Berger et al.(2008) Isl2_3430	0.867	1.000
ISL2 M03177_2.00	Homo sapiens	YTAAKTGB	VCAMTTAR	SELEX Jolma et al.(2013) ISL2_1	0.867	1.000
ISL1 M04908_2.00	Homo sapiens	BTAAKTGS	SCAMTTAV	SELEX Yin et al.(2017) ISL1_eDBD_HT-SELEX	0.867	1.000
ISL1 M04910_2.00	Homo sapiens	NTAAKTGS	SCAMTTAN	SELEX Yin et al.(2017) ISL1_FL_HT-SELEX	0.867	1.000
ISL2 M05204_2.00	Homo sapiens	NTAAKTGS	SCAMTTAN	SELEX Yin et al.(2017) ISL2_eDBD_HT-SELEX	0.867	1.000
ISL1 M09128_2.00	Homo sapiens	NYWRAKKGV	BCMMTYWRN	Misc Kulakovskiy et al.(2013) ISL1_HUMAN.H11MO.0.A	0.867	1.000
Isl1 M09209_2.00	Mus musculus	NYWRAKKGV	BCMMTYWRN	Misc Kulakovskiy et al.(2013) ISL1_MOUSE.H11MO.0.A	0.867	1.000
Isl1 M09578_2.00	Mus musculus	YTAAKKGV	BCMMTTAR	Misc Heinz et al.(2010) Neuron-Isl1_GSE31456	0.867	1.000
ISL1 M10634_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$ISL1_Q3	0.867	1.000
ISL1 M10635_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$ISL1_Q6	0.867	1.000
ISL1 M04909_2.00	Homo sapiens	BTAAKTGS	SCAMTTAV	SELEX Yin et al.(2017) ISL1_eDBD_Methyl-HT-SELEX	0.867	1.000
ISL1 M04911_2.00	Homo sapiens	BTAAKTGS	SCAMTTAV	SELEX Yin et al.(2017) ISL1_FL_Methyl-HT-SELEX	0.867	1.000
ISL2 M05205_2.00	Homo sapiens	NTAAKTGN	NCAMTTAN	SELEX Yin et al.(2017) ISL2_eDBD_Methyl-HT-SELEX	0.867	1.000
ISL2B_ONCTS M10798_2.00	Oncorhynchus tshawytscha	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$ISL2_02	0.866	0.982
ISL2B_ONCTS M10799_2.00	Oncorhynchus tshawytscha	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$ISL2_03	0.866	0.982
ISL2B_ONCTS M10800_2.00	Oncorhynchus tshawytscha	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$ISL2_04	0.866	0.982
ISL2B_ONCTS M10801_2.00	Oncorhynchus tshawytscha	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$ISL2_05	0.866	0.982
tup M06498_2.00	Drosophila melanogaster	WTAATKG	CMATTAW	B1H Mathelier et al.(2014) MA0248.1	0.864	0.965
tup M06270_2.00	Drosophila melanogaster	SWTAATKG	CMATTAWS	B1H Zhu et al.(2011) Tup_Cell_FBgn0003896	0.864	0.965
tup M06271_2.00	Drosophila melanogaster	NYTAATKRV	BYMATTARN	B1H Zhu et al.(2011) tup_SOLEXA_10_FBgn0003896	0.864	0.965
tup M06272_2.00	Drosophila melanogaster	YTAATKR	YMATTAR	B1H Zhu et al.(2011) Tup_SOLEXA_FBgn0003896	0.864	0.965
CBG04010 M01242_2.00	Caenorhabditis briggsae	NNKTAATDDMN	NKHHATTAMNN	PBM Lambert et al.(2019) pTH11489	0.835	0.772
NEMVEDRAFT_v1g81309 M02152_2.00	Nematostella vectensis	NTAATDNNN	NNNHATTAN	PBM Weirauch et al.(2014) pTH5477	0.636	0.351
NOTO M03241_2.00	Homo sapiens	NNTAATKWRN	NYWMATTANN	SELEX Jolma et al.(2013) NOTO_1	0.631	0.368
NOTO M05390_2.00	Homo sapiens	BTAATKRV	BYMATTAV	SELEX Yin et al.(2017) NOTO_eDBD_HT-SELEX	0.631	0.368
NOTO M05391_2.00	Homo sapiens	BTMATKRV	BYMATKAV	SELEX Yin et al.(2017) NOTO_eDBD_Methyl-HT-SELEX	0.631	0.368
PHOX2B M00278_2.00	Homo sapiens	NNNNNRY	RYNNNNN	PBM Barrera et al.(2016) PHOX2B_Q143R	0.623	0.368
Noto M02101_2.00	Mus musculus	NNHHATDDNN	NNHHATDDNN	PBM Weirauch et al.(2014) pTH6268	0.613	0.351
VSX1 M00269_2.00	Homo sapiens	NNWAAYNNN	NNNRTTWNN	PBM Barrera et al.(2016) VSX1_REF	0.608	0.386
Vsx1 M00459_2.00	Mus musculus	NNTAATDDN	NHHATTANN	PBM Berger et al.(2008) Vsx1_1728	0.608	0.386
Vsx1 M03267_2.00	Mus musculus	NTAATTRN	NYAATTAN	SELEX Jolma et al.(2013) Vsx1_1	0.608	0.386
VSX1 M00266_2.00	Homo sapiens	NNTAAYNNN	NNNRTTANN	PBM Barrera et al.(2016) VSX1_G160D	0.608	0.386
Sebox M02097_2.00	Mus musculus	NHTTAATTAN	NTAATTAADN	PBM Weirauch et al.(2014) pTH6379	0.605	0.421
ceh-5 M02179_2.00	Caenorhabditis elegans	NNTAATDDN	NHHATTANN	PBM Weirauch et al.(2014) pTH6562	0.604	0.368
SHOX M02095_2.00	Homo sapiens	NTAATTRN	NYAATTAN	PBM Weirauch et al.(2014) pTH5805	0.601	0.404
Shox2 M00439_2.00	Mus musculus	NTAATDDN	NHHATTAN	PBM Berger et al.(2008) Shox2_2641	0.601	0.404
SHOX M03232_2.00	Homo sapiens	NTAATTRN	NYAATTAN	SELEX Jolma et al.(2013) SHOX_1	0.601	0.404
SHOX2 M03204_2.00	Homo sapiens	BTAATTRN	NYAATTAV	SELEX Jolma et al.(2013) SHOX2_1	0.601	0.404
Shox2 M03263_2.00	Mus musculus	NTAATTRN	NYAATTAN	SELEX Jolma et al.(2013) Shox2_1	0.601	0.404
CG5369 M03876_2.00	Drosophila melanogaster	TAATTHVATTA	TAATBDAATTA	SELEX Nitta et al.(2015) CG5369_1	0.601	0.404
CG5369 M03877_2.00	Drosophila melanogaster	TAATTRNNTAATBN	NVATTANNYAATTA	SELEX Nitta et al.(2015) CG5369_2	0.601	0.404
CG5369 M03878_2.00	Drosophila melanogaster	TAATTVRATWA	TWATYBAATTA	SELEX Nitta et al.(2015) CG5369_3	0.601	0.404
SHOX M05366_2.00	Homo sapiens	NTAATTRV	BYAATTAN	SELEX Yin et al.(2017) SHOX_eDBD_HT-SELEX	0.601	0.404
Shox2 M10772_2.00	Rattus norvegicus	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$SHOX2_05	0.601	0.404
SHOX M05367_2.00	Homo sapiens	NTAATTRV	BYAATTAN	SELEX Yin et al.(2017) SHOX_eDBD_Methyl-HT-SELEX_1	0.601	0.404
SHOX M05368_2.00	Homo sapiens	NTAAYGAN	NTCRTTAN	SELEX Yin et al.(2017) SHOX_eDBD_Methyl-HT-SELEX_2	0.601	0.404
C4B866_NEMVE M02052_2.00	Nematostella vectensis	NNTTAATTARNN	NNYTAATTAANN	PBM Weirauch et al.(2014) pTH6176	0.600	0.421
For this family, TFs with SR scores > 0.599* will likely have a similar motif*

DNA Binding Domains

Protein ID	Domain	From	To	Sequence
ENSCHOP00000011070	Homeodomain	182	238	TRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK

Links
Other Homeodomain family TFs
Other *Choloepus hoffmanni* TFs

604 Related TFs

Name	Species	Gene ID	Motif Evidence	SR Score	Action
BGIOSGA029518	Oryza indica	BGIOSGA029518	N	0.000
BRADI4G34022	Brachypodium distachyon	BRADI4G34022	I	0.000
GRMZM2G004531	Zea mays	GRMZM2G004531	N	0.000
LPERR09G11150	Leersia perrieri	LPERR09G11150	N	0.000
OBART09G15000	Oryza barthii	OBART09G15000	N	0.000
OGLUM09G15640	Oryza glumaepatula	OGLUM09G15640	N	0.000
OMERI09G11680	Oryza meridionalis	OMERI09G11680	N	0.000
ONIVA09G15620	Oryza nivara	ONIVA09G15620	N	0.000
OPUNC09G13450	Oryza punctata	OPUNC09G13450	N	0.000
ORGLA09G0115600	Oryza glaberrima	ORGLA09G0115600	N	0.000
ORUFI09G16180	Oryza rufipogon	ORUFI09G16180	N	0.000
OS09G0493700	Oryza sativa	OS09G0493700	N	0.000
Pavir.J04800	Panicum virgatum	Pavir.J04800	N	0.000
Sb02g028750	Sorghum bicolor	Sb02g028750	N	0.000
Si029088m.g	Setaria italica	Si029088m.g	N	0.000

ISL1 (Choloepus hoffmanni) Homeodomain

TF Information

Directly determined binding motifs

Motifs from related TFs

DNA Binding Domains

Links

604 Related TFs

ISL1 **(Choloepus hoffmanni)
Homeodomain**