HMBOX1 (Homo sapiens)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSG00000147421 T209858_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
HMBOX1
M03167_2.00		 Homo sapiens
BKTAACTARB
VYTAGTTAMV		 SELEX
Jolma et al.(2013)
HMBOX1_1		 (Direct) (Direct)
HMBOX1
M05180_2.00		 Homo sapiens
BTAACYAGB
VCTRGTTAV		 SELEX
Yin et al.(2017)
HMBOX1_eDBD_HT-SELEX		 (Direct) (Direct)
HMBOX1
M05181_2.00		 Homo sapiens
NTAACTAGB
VCTAGTTAN		 SELEX
Yin et al.(2017)
HMBOX1_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Hmbox1
M00419_2.00 		Mus musculus
NNNGWNNN
NNNWCNNN		 PBM
Berger et al.(2008)
Hmbox1_2674 		0.867 1.000
Hnf1b
M00408_2.00 		Mus musculus
NNHWCNNN
NNNGWDNN		 PBM
Berger et al.(2008)
Tcf2_0913 		0.638 0.368
Hnf1a
M00171_2.00 		Mus musculus
HTAAYYNN
NNRRTTAD		 PBM
Badis et al.(2009)
Tcf1_2666 		0.638 0.368
Hnf1a
M00444_2.00 		Mus musculus
HTAAYYNNN
NNNRRTTAD		 PBM
Berger et al.(2008)
Tcf1_2666 		0.638 0.368
HNF1A
M03150_2.00 		Homo sapiens
NGTTAATNATTAAYN
NRTTAATNATTAACN		 SELEX
Jolma et al.(2013)
HNF1A_1 		0.638 0.368
HNF1B
M03245_2.00 		Homo sapiens
GTTAATNATTAAY
RTTAATNATTAAC		 SELEX
Jolma et al.(2013)
HNF1B_1 		0.638 0.368
HNF1B
M03246_2.00 		Homo sapiens
NGTTAATNATTAAYN
NRTTAATNATTAACN		 SELEX
Jolma et al.(2013)
HNF1B_2 		0.638 0.368
HNF1A
M09144_2.00 		Homo sapiens
DGTTAATKATTAACH
DGTTAATMATTAACH		 Misc
Kulakovskiy et al.(2013)
HNF1A_HUMAN.H11MO.0.C 		0.638 0.368
HNF1B
M09168_2.00 		Homo sapiens
DGTTAATRATTAACH
DGTTAATYATTAACH		 Misc
Kulakovskiy et al.(2013)
HNF1B_HUMAN.H11MO.0.A 		0.638 0.368
Hnf1a
M09191_2.00 		Mus musculus
RGTTAATNWTTDMHN
NDKHAAWNATTAACY		 Misc
Kulakovskiy et al.(2013)
HNF1A_MOUSE.H11MO.0.A 		0.638 0.368
Hnf1b
M09179_2.00 		Mus musculus
DGTTAATRATTAACH
DGTTAATYATTAACH		 Misc
Kulakovskiy et al.(2013)
HNF1B_MOUSE.H11MO.0.A 		0.638 0.368
HNF1A
M10690_2.00 		Homo sapiens
RGTTAATDWTTRMHV
BDKYAAWHATTAACY		 Transfac
Matys et al.(2006)
V$HNF1_01 		0.638 0.368
HNF1A
M10691_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HNF1A_Q4 		0.638 0.368
HNF1A
M10692_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HNF1A_Q5 		0.638 0.368
HNF1B
M10758_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HNF1B_Q6_01 		0.638 0.368
HNF1B
M10759_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HNF1B_Q6 		0.638 0.368
HNF1A
M10693_2.00 		Homo sapiens
DGBTAATBAWTHAMYWM
KWRKTDAWTVATTAVCH		 Transfac
Matys et al.(2006)
V$HNF1_C 		0.638 0.368
HNF1B
M10760_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$LFA1_Q6 		0.638 0.368
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000287701 Homeodomain 268 339
ENSP00000380516 Homeodomain 268 339
ENSP00000430059 Homeodomain 268 339
ENSP00000430110 Homeodomain 268 339
ENSP00000452827 Homeodomain 268 339
ENSP00000453185 Homeodomain 268 310
ENSP00000453211 Homeodomain 268 339
ENSP00000475196 Homeodomain 268 339

Links

Other Homeodomain family TFs
Other Homo sapiens TFs

237 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
Cla010506 Citrullus lanatus Cla010506 N 0.000
Cucsa.158390 Cucumis sativus Cucsa.158390 N 0.000
GLYMA18G49320 Glycine max GLYMA18G49320 N 0.000
mgf001503m Mimulus guttatus mgf001503m N 0.000
PK18828.1 Cannabis sativa PK18828.1 N 0.000
VIT_01s0026g02030 Vitis vinifera VIT_01s0026g02030 N 0.000