CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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ceh-54
(
Caenorhabditis elegans
)
Homeodomain
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00046 (Homeobox)
IPR001356
WBGene00020485
T224674_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in neurons. [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
ceh-54
M02188_2.00
Caenorhabditis elegans
HTAATTRVN
NBYAATTAD
PBM
Weirauch et al.(2014)
pTH5643
(Direct)
(Direct)
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
Esx1
M00424_2.00
Mus musculus
NYTAATWR
YWATTARN
PBM
Berger et al.(2008)
Esx1_3124
0.695
0.526
HESX1
M00309_2.00
Homo sapiens
HTAATTRGN
NCYAATTAD
PBM
Barrera et al.(2016)
HESX1_REF
0.626
0.544
HESX1
M00307_2.00
Homo sapiens
TAATTRNN
NNYAATTA
PBM
Barrera et al.(2016)
HESX1_N125S
0.626
0.544
P79681_ACIBE
M02200_2.00
Acipenser baerii
DTAATTRB
VYAATTAH
PBM
Weirauch et al.(2014)
pTH6156
0.626
0.526
HESX1
M00308_2.00
Homo sapiens
NATAHATRN
NYATDTATN
PBM
Barrera et al.(2016)
HESX1_R160C
0.626
0.526
ENSCING00000016045
M02078_2.00
Ciona intestinalis
NNYTAATTRGN
NCYAATTARNN
PBM
Weirauch et al.(2014)
pTH6551
0.611
0.596
HESX1
M00306_2.00
Homo sapiens
WRATDRNN
NNYHATYW
PBM
Barrera et al.(2016)
HESX1_E149K
0.606
0.526
For this family, TFs with SR scores >
0.599
will likely have a similar motif
Experimental Constructs
Motif ID
Domain
From
To
Sequence
M02188_2.00
Homeodomain
1
57
KRNRITFDANQIDEMEKVFAENQYPDTMSREKLANKIQLHEERVQIWFQNRRAKYRR
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
T13C5.4
Homeodomain
45
101
KRNRITFDANQIDEMEKVFAENQYPDTMSREKLANKIQLHEERVQIWFQNRRAKYRR
Links
Other
Homeodomain
family TFs
Other
Caenorhabditis elegans
TFs
112 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy