ceh-54 (Caenorhabditis elegans)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 WBGene00020485 T224674_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in neurons. [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ceh-54
M02188_2.00		 Caenorhabditis elegans
HTAATTRVN
NBYAATTAD		 PBM
Weirauch et al.(2014)
pTH5643		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Esx1
M00424_2.00 		Mus musculus
NYTAATWR
YWATTARN		 PBM
Berger et al.(2008)
Esx1_3124 		0.695 0.526
HESX1
M00309_2.00 		Homo sapiens
HTAATTRGN
NCYAATTAD		 PBM
Barrera et al.(2016)
HESX1_REF 		0.626 0.544
HESX1
M00307_2.00 		Homo sapiens
TAATTRNN
NNYAATTA		 PBM
Barrera et al.(2016)
HESX1_N125S 		0.626 0.544
P79681_ACIBE
M02200_2.00 		Acipenser baerii
DTAATTRB
VYAATTAH		 PBM
Weirauch et al.(2014)
pTH6156 		0.626 0.526
HESX1
M00308_2.00 		Homo sapiens
NATAHATRN
NYATDTATN		 PBM
Barrera et al.(2016)
HESX1_R160C 		0.626 0.526
ENSCING00000016045
M02078_2.00 		Ciona intestinalis
NNYTAATTRGN
NCYAATTARNN		 PBM
Weirauch et al.(2014)
pTH6551 		0.611 0.596
HESX1
M00306_2.00 		Homo sapiens
WRATDRNN
NNYHATYW		 PBM
Barrera et al.(2016)
HESX1_E149K 		0.606 0.526
For this family, TFs with SR scores > 0.599 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M02188_2.00 Homeodomain 1 57

DNA Binding Domains

Protein ID Domain From To Sequence
T13C5.4 Homeodomain 45 101

Links

Other Homeodomain family TFs
Other Caenorhabditis elegans TFs

112 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CBN18011 Caenorhabditis brenneri CBN18011 I 0.851
CBG14858 Caenorhabditis briggsae CBG14858 I 0.841
CRE00191 Caenorhabditis remanei CRE00191 I 0.830
CJA11788 Caenorhabditis japonica CJA11788 I 0.798
ENSCHOG00000002622 Choloepus hoffmanni ENSCHOG00000002622 I 0.755
Esx1 Mus musculus ENSMUSG00000023443 D 0.695
ML021120a Mnemiopsis leidyi ML021120a I 0.695
Esx1 Rattus norvegicus ENSRNOG00000048011 I 0.695
ENSCAFG00000023214 Canis familiaris ENSCAFG00000023214 I 0.690
ENSSTOG00000023781 Ictidomys tridecemlineatus ENSSTOG00000023781 I 0.682
SEBOX Cavia porcellus ENSCPOG00000005498 I 0.682
SEBOX Pteropus vampyrus ENSPVAG00000002882 I 0.682
TELCIR_13423 Teladorsagia circumcincta TELCIR_13423 I 0.681
H311_03552 Anncaliia algerae H311_03552 I 0.681
EDEG_02526 Edhazardia aedis EDEG_02526 I 0.669
Sakowv30037698m.g Saccoglossus kowalevskii Sakowv30037698m.g I 0.669
H311_01337 Anncaliia algerae H311_01337 I 0.668
H311_02306 Anncaliia algerae H311_02306 I 0.668
NERG_00545 Nematocida sp NERG_00545 I 0.663
ENSTBEG00000007985 Tupaia belangeri ENSTBEG00000007985 I 0.662
GB43703 Apis mellifera GB43703 I 0.652
CGI_10013213 Crassostrea gigas CGI_10013213 I 0.643
Cmyd_10020629 Chelonia mydas Cmyd_10020629 I 0.628
Aan_R010087 Calypte anna Aan_R010087 I 0.628
ENSPANG00000023827 Papio anubis ENSPANG00000023827 I 0.626
HESX1 Pteropus vampyrus ENSPVAG00000013347 I 0.626
HESX1 Pan troglodytes ENSPTRG00000015044 I 0.626
HESX1 Procavia capensis ENSPCAG00000003678 I 0.626
HESX1 Tupaia belangeri ENSTBEG00000017505 I 0.626
HESX1 Sorex araneus ENSSARG00000004783 I 0.626
HESX1 Sus scrofa ENSSSCG00000021207 I 0.626
ENSPPYG00000013775 Pongo abelii ENSPPYG00000013775 I 0.626
ENSSHAG00000012478 Sarcophilus harrisii ENSSHAG00000012478 I 0.626
ENSSTOG00000000375 Ictidomys tridecemlineatus ENSSTOG00000000375 I 0.626
Afo_R011795 Aptenodytes forsteri Afo_R011795 I 0.626
P79681_ACIBE Acipenser baerii P79681_ACIBE D 0.626
Tal_R005145 Tyto alba Tal_R005145 I 0.626
CAA49768 Xenopus laevis CAA49768 I 0.626
hesx1 Xenopus tropicalis XB-GENE-483193 I 0.626
hesx1.L Xenopus laevis XB-GENE-864952 I 0.626
hesx1.S Xenopus laevis XB-GENE-6252654 I 0.626
Pvit_14185 Pogona vitticeps Pvit_14185 I 0.626
Gfo_R015056 Geospiza fortis Gfo_R015056 I 0.626
HESX1 Ochotona princeps ENSOPRG00000005159 I 0.626
HESX1 Tursiops truncatus ENSTTRG00000009140 I 0.626
Alligator_sinensis_CCG003505.1 Alligator sinensis Alligator_sinensis_CCG003505.1 I 0.626
Brh_R006162 Buceros rhinoceros Brh_R006162 I 0.626
ENSP00000419615 Macaca fascicularis ENSP00000419615 I 0.626
ENSBTAP00000001886-D1 Bos grunniens ENSBTAP00000001886-D1 I 0.626
HESX1 Taeniopygia guttata ENSTGUG00000007186 I 0.626
ENSPSIG00000007922 Pelodiscus sinensis ENSPSIG00000007922 I 0.626
HESX1 Dasypus novemcinctus ENSDNOG00000003677 I 0.626
ENSCSAG00000012779 Chlorocebus sabaeus ENSCSAG00000012779 I 0.626
HESX1 Otolemur garnettii ENSOGAG00000031045 I 0.626
HESX1 Equus caballus ENSECAG00000007740 I 0.626
ENSFALG00000008487 Ficedula albicollis ENSFALG00000008487 I 0.626
HESX1 Homo sapiens ENSG00000163666 D 0.626
HESX1 Felis catus ENSFCAG00000024266 I 0.626
HESX1 Callithrix jacchus ENSCJAG00000010981 I 0.626
ENSCHOG00000013897 Choloepus hoffmanni ENSCHOG00000013897 I 0.626
ENSAMEG00000011722 Ailuropoda melanoleuca ENSAMEG00000011722 I 0.626
ENSACAG00000005724 Anolis carolinensis ENSACAG00000005724 I 0.626
ENSAMXG00000004052 Astyanax mexicanus ENSAMXG00000004052 I 0.626
ENSAPLG00000005083 Anas platyrhynchos ENSAPLG00000005083 I 0.626
HESX1 Canis familiaris ENSCAFG00000007995 I 0.626
HESX1 Bos taurus ENSBTAG00000001439 I 0.626
HESX1 Gallus gallus ENSGALG00000005506 I 0.626
HESX1 Cavia porcellus ENSCPOG00000012741 I 0.626
ENSMPUG00000016854 Mustela putorius furo ENSMPUG00000016854 I 0.626
HESX1 Monodelphis domestica ENSMODG00000012324 I 0.626
HESX1 Macaca mulatta ENSMMUG00000007224 I 0.626
ENSMPUG00000018366 Mustela putorius furo ENSMPUG00000018366 I 0.626
ENSMPUG00000018780 Mustela putorius furo ENSMPUG00000018780 I 0.626
ENSOARG00000014637 Ovis aries ENSOARG00000014637 I 0.626
HESX1 Ornithorhynchus anatinus ENSOANG00000015103 I 0.626
HESX1 Gorilla gorilla ENSGGOG00000006213 I 0.626
HESX1 Myotis lucifugus ENSMLUG00000008636 I 0.626
ENSNLEG00000007255 Nomascus leucogenys ENSNLEG00000007255 I 0.626
ENSLOCG00000013317 Lepisosteus oculatus ENSLOCG00000013317 I 0.626
HESX1 Loxodonta africana ENSLAFG00000032415 I 0.626
HESX1 Meleagris gallopavo ENSMGAG00000006238 I 0.626
ENSLACG00000011013 Latimeria chalumnae ENSLACG00000011013 I 0.626
A_06265 Schistosoma haematobium A_06265 I 0.622
estExt_gwp.C_780115 Branchiostoma floridae estExt_gwp.C_780115 I 0.622
CDX4 Callithrix jacchus ENSCJAG00000011367 I 0.622
Smp_000075 Schistosoma mansoni Smp_000075 I 0.622
estExt_GenewiseH_1.C_4210013 Branchiostoma floridae estExt_GenewiseH_1.C_4210013 I 0.622
CapteG29885 Capitella teleta CapteG29885 I 0.617
GLOINDRAFT_4254 Rhizophagus irregularis GLOINDRAFT_4254 I 0.616
BOTBODRAFT_45725 Botryobasidium botryosum BOTBODRAFT_45725 I 0.615
CapteG99648 Capitella teleta CapteG99648 I 0.612
ENSACAG00000026013 Anolis carolinensis ENSACAG00000026013 I 0.612
ENSCSAVG00000011699 Ciona savignyi ENSCSAVG00000011699 I 0.611
CORT_0B02840 Candida orthopsilosis CORT_0B02840 I 0.611
Minc16296 Meloidogyne incognita Minc16296 I 0.611
ENSCING00000016045 Ciona intestinalis ENSCING00000016045 D 0.611
TsM_001238800 Taenia solium TsM_001238800 I 0.611
TriadG60748 Trichoplax adhaerens TriadG60748 I 0.610
scaffold258-EXSNAP2012.18 Pristionchus exspectatus scaffold258-EXSNAP2012.18 I 0.610
CapteG109027 Capitella teleta CapteG109027 I 0.609
BXY_1075500 Bursaphelenchus xylophilus BXY_1075500 I 0.609
T265_11607 Opisthorchis viverrini T265_11607 I 0.606
csin107777 Clonorchis sinensis csin107777 I 0.606
LCUP017283 Lucilia cuprina LCUP017283 I 0.605
MDOA003070 Musca domestica MDOA003070 I 0.605
MDOA000990 Musca domestica MDOA000990 I 0.605
T265_03777 Opisthorchis viverrini T265_03777 I 0.603
csin111676 Clonorchis sinensis csin111676 I 0.603
NEMVEDRAFT_v1g68616 Nematostella vectensis NEMVEDRAFT_v1g68616 I 0.600
CGI_10015407 Crassostrea gigas CGI_10015407 I 0.600
HelroG148581 Helobdella robusta HelroG148581 I 0.599
NEMVEDRAFT_v1g110792 Nematostella vectensis NEMVEDRAFT_v1g110792 I 0.599