IRF3 (Homo sapiens)
IRF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00605 (IRF) IPR001346 ENSG00000126456 T244079_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
IRF3
M03331_2.00		 Homo sapiens
NNRRAANGGAAACCGAAACYR
YRGTTTCGGTTTCCNTTYYNN		 SELEX
Jolma et al.(2013)
IRF3_1		 (Direct) (Direct)
IRF3
M05531_2.00		 Homo sapiens
DCVGTTTCSNSGAAACCGMAASN
NSTTKCGGTTTCSNSGAAACBGH		 SELEX
Yin et al.(2017)
IRF3_eDBD_HT-SELEX		 (Direct) (Direct)
IRF3
M05532_2.00		 Homo sapiens
KCDSTTTCCHGGAAAMNRAWAV
BTWTYNKTTTCCDGGAAASHGM		 SELEX
Yin et al.(2017)
IRF3_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)
IRF3
M05533_2.00		 Homo sapiens
HSGAAAVBGAAACYGAAACN
NGTTTCRGTTTCVBTTTCSD		 SELEX
Yin et al.(2017)
IRF3_FL_HT-SELEX		 (Direct) (Direct)
IRF3
M05534_2.00		 Homo sapiens
HGGAAABBGAAASBGAAASN
NSTTTCVSTTTCVVTTTCCD		 SELEX
Yin et al.(2017)
IRF3_FL_Methyl-HT-SELEX		 (Direct) (Direct)
IRF3
M09234_2.00		 Homo sapiens
RRRARDGAAAVDGRAASNRA
TYNSTTYCHBTTTCHYTYYY		 Misc
Kulakovskiy et al.(2013)
IRF3_HUMAN.H11MO.0.B		 (Direct) (Direct)
IRF3
M10883_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF3_Q3		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Irf3
M00174_2.00 		Mus musculus
RDWNBGMAAS
STTKCVNWHY		 PBM
Badis et al.(2009)
Irf3_3985 		0.856 0.856
Irf3
M09241_2.00 		Mus musculus
RRRARDGAAAVDGRAASNRA
TYNSTTYCHBTTTCHYTYYY		 Misc
Kulakovskiy et al.(2013)
IRF3_MOUSE.H11MO.0.A 		0.856 0.856
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000310127 IRF 7 110
ENSP00000366344 IRF 7 110
ENSP00000400378 IRF 7 103
ENSP00000469113 IRF 7 110
ENSP00000470140 IRF 7 110
ENSP00000470431 IRF 7 110
ENSP00000470436 IRF 7 110
ENSP00000470905 IRF 7 102
ENSP00000471358 IRF 7 110
ENSP00000471896 IRF 7 110
ENSP00000472223 IRF 7 110
ENSP00000473128 IRF 7 110
ENSP00000473176 IRF 7 110

Links

Other IRF family TFs
Other Homo sapiens TFs

38 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
Aan_R003503 Calypte anna Aan_R003503 I
Aan_R008211 Calypte anna Aan_R008211 I
Afo_R001109 Aptenodytes forsteri Afo_R001109 I
Afo_R013473 Aptenodytes forsteri Afo_R013473 I
Alligator_sinensis_CCG008952.1 Alligator sinensis Alligator_sinensis_CCG008952.1 I
Alligator_sinensis_CCG015471.1 Alligator sinensis Alligator_sinensis_CCG015471.1 I
Brh_R005582 Buceros rhinoceros Brh_R005582 I
Cmyd_10017824 Chelonia mydas Cmyd_10017824 I
ENSAMXG00000024918 Astyanax mexicanus ENSAMXG00000024918 I
ENSAPLG00000002158 Anas platyrhynchos ENSAPLG00000002158 I
ENSCSAG00000013356 Chlorocebus sabaeus ENSCSAG00000013356 I
ENSFALG00000006543 Ficedula albicollis ENSFALG00000006543 I
ENSFALG00000014495 Ficedula albicollis ENSFALG00000014495 I
ENSGALG00000001403 Gallus gallus ENSGALG00000001403 I
ENSGALG00000026718 Gallus gallus ENSGALG00000026718 I
ENSLACG00000007028 Latimeria chalumnae ENSLACG00000007028 I
ENSLOCG00000002169 Lepisosteus oculatus ENSLOCG00000002169 I
ENSMGAG00000005397 Meleagris gallopavo ENSMGAG00000005397 I
ENSMPUG00000003198 Mustela putorius furo ENSMPUG00000003198 I
ENSONIG00000014335 Oreochromis niloticus ENSONIG00000014335 I
ENSP00000384889 Macaca fascicularis ENSP00000384889 I
ENSPANG00000024301 Papio anubis ENSPANG00000024301 I
ENSPFOG00000020465 Poecilia formosa ENSPFOG00000020465 I
ENSPPYG00000012022 Pongo abelii ENSPPYG00000012022 I
ENSPSIG00000000839 Pelodiscus sinensis ENSPSIG00000000839 I
ENSPSIG00000000992 Pelodiscus sinensis ENSPSIG00000000992 I
ENSPSIG00000007902 Pelodiscus sinensis ENSPSIG00000007902 I
ENSSSCG00000021196 Sus scrofa ENSSSCG00000021196 I
ENSSTOG00000006360 Ictidomys tridecemlineatus ENSSTOG00000006360 I
ENSXMAG00000020311 Xiphophorus maculatus ENSXMAG00000020311 I
Gfo_R010813 Geospiza fortis Gfo_R010813 I
hic1 Oryzias latipes ENSORLG00000004895 I
HIC1 Taeniopygia guttata ENSTGUG00000005835 I
hic1 Gasterosteus aculeatus ENSGACG00000010848 I
hic1 Takifugu rubripes ENSTRUG00000004590 I
Hic1 Mus musculus ENSMUSG00000043099 D
HIC1 Cavia porcellus ENSCPOG00000020382 I
hic1l Takifugu rubripes ENSTRUG00000013139 I
hic1l Gasterosteus aculeatus ENSGACG00000004268 I
hic2 Xenopus tropicalis XB-GENE-960044 I
HIC2 Taeniopygia guttata ENSTGUG00000008699 I
HIC2 Procavia capensis ENSPCAG00000015907 I
HIC2 Pteropus vampyrus ENSPVAG00000000111 I
HIC2 Bos taurus ENSBTAG00000005951 I
HIC2 Canis familiaris ENSCAFG00000032493 I
HIC2 Cavia porcellus ENSCPOG00000001134 I
hic2 Danio rerio ENSDARG00000100497 I
HIC2 Dasypus novemcinctus ENSDNOG00000003162 I
HIC2 Equus caballus ENSECAG00000017997 I
HIC2 Felis catus ENSFCAG00000023903 I
HIC2 Homo sapiens ENSG00000169635 D
HIC2 Meleagris gallopavo ENSMGAG00000000949 I
HIC2 Microcebus murinus ENSMICG00000005154 I
HIC2 Myotis lucifugus ENSMLUG00000009669 I
Hic2 Mus musculus ENSMUSG00000050240 I
HIC2 Oryctolagus cuniculus ENSOCUG00000010516 I
HIC2 Otolemur garnettii ENSOGAG00000030274 I
HIC2 Pan troglodytes ENSPTRG00000014112 I
Hic2 Rattus norvegicus ENSRNOG00000051458 I
Myotis_brandtii_HIC2_10021802 Myotis brandtii Myotis_brandtii_HIC2_10021802 I
Ogr08090 Ophisaurus gracilis Ogr08090 I
Pvit_18806 Pogona vitticeps Pvit_18806 I
Tal_R003180 Tyto alba Tal_R003180 I
XP_002937184 Xenopus tropicalis XP_002937184 I