IRF7 (Homo sapiens)
IRF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00605 (IRF) IPR001346 ENSG00000185507 T244084_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
IRF7
M03337_2.00		 Homo sapiens
HCGAAAVYGAAAVT
ABTTTCRBTTTCGD		 SELEX
Jolma et al.(2013)
IRF7_1		 (Direct) (Direct)
IRF7
M03338_2.00		 Homo sapiens
RAANCGAAAWTCGNTTY
RAANCGAWTTTCGNTTY		 SELEX
Jolma et al.(2013)
IRF7_2		 (Direct) (Direct)
IRF7
M05547_2.00		 Homo sapiens
NCGAAAVYGAAANYN
NRNTTTCRBTTTCGN		 SELEX
Yin et al.(2017)
IRF7_eDBD_HT-SELEX		 (Direct) (Direct)
IRF7
M05548_2.00		 Homo sapiens
NNGAAARTGAAAVYR
YRBTTTCAYTTTCNN		 SELEX
Yin et al.(2017)
IRF7_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)
IRF7
M09238_2.00		 Homo sapiens
RAAASYRAAW
WTTYRSTTTY		 Misc
Kulakovskiy et al.(2013)
IRF7_HUMAN.H11MO.0.C		 (Direct) (Direct)
IRF7
M10894_2.00		 Homo sapiens
NNSGAAWNYGAAANYBDV
BHVRNTTTCRNWTTCSNN		 Transfac
Matys et al.(2006)
V$IRF7_01		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Irf7
M02255_2.00 		Mus musculus
DAHNNGAAAN
NTTTCNNDTH		 PBM
Weirauch et al.(2014)
pTH3475 		0.769 0.769
Irf7
M09244_2.00 		Mus musculus
RAAASYRAAW
WTTYRSTTTY		 Misc
Kulakovskiy et al.(2013)
IRF7_MOUSE.H11MO.0.C 		0.769 0.769
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000329411 IRF 26 138
ENSP00000331803 IRF 13 125
ENSP00000380697 IRF 26 138
ENSP00000380700 IRF 26 138
ENSP00000380704 IRF 13 125
ENSP00000432403 IRF 26 138
ENSP00000433903 IRF 13 125
ENSP00000434524 IRF 13 118
ENSP00000434607 IRF 13 125
ENSP00000436696 IRF 13 125

Links

Other IRF family TFs
Other Homo sapiens TFs

29 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSAMEG00000013892 Ailuropoda melanoleuca ENSAMEG00000013892 I
ENSBTAP00000031815-D1 Bos grunniens ENSBTAP00000031815-D1 I
ENSCSAG00000002477 Chlorocebus sabaeus ENSCSAG00000002477 I
ENSMMUP00000031524 Macaca fascicularis ENSMMUP00000031524 I
ENSMPUG00000002477 Mustela putorius furo ENSMPUG00000002477 I
ENSOARG00000013335 Ovis aries ENSOARG00000013335 I
ENSPANG00000014697 Papio anubis ENSPANG00000014697 I
ENSPPYG00000010260 Pongo abelii ENSPPYG00000010260 I
ENSPTRG00000011309 Pan troglodytes ENSPTRG00000011309 I
ENSSTOG00000022900 Ictidomys tridecemlineatus ENSSTOG00000022900 I
IRF3 Sorex araneus ENSSARG00000006248 I
Irf3 Rattus norvegicus ENSRNOG00000043388 I
IRF3 Pteropus vampyrus ENSPVAG00000010968 I
IRF3 Sus scrofa ENSSSCG00000003178 I
IRF3 Procavia capensis ENSPCAG00000008633 I
IRF3 Tursiops truncatus ENSTTRG00000005531 I
IRF3 Oryctolagus cuniculus ENSOCUG00000027558 I
IRF3 Ochotona princeps ENSOPRG00000001971 I
IRF3 Otolemur garnettii ENSOGAG00000011935 I
Irf3 Mus musculus ENSMUSG00000003184 D
IRF3 Macaca mulatta ENSMMUG00000022735 I
IRF3 Myotis lucifugus ENSMLUG00000023427 I
IRF3 Gorilla gorilla ENSGGOG00000000499 I
IRF3 Homo sapiens ENSG00000126456 D
IRF3 Felis catus ENSFCAG00000006074 I
IRF3 Equus caballus ENSECAG00000018265 I
IRF3 Dasypus novemcinctus ENSDNOG00000040858 I
IRF3 Cavia porcellus ENSCPOG00000026146 I
IRF3 Callithrix jacchus ENSCJAG00000003637 I
IRF3 Bos taurus ENSBTAG00000006633 I