CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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nhr-168
(
Caenorhabditis elegans
)
Nuclear receptor
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00105 (zf-C4)
IPR001628
WBGene00008221
T306261_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in anatomical structure development; cell differentiation; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in seam cell. Human ortholog(s) of this gene implicated in Fanconi renotubular syndrome 4; familial combined hyperlipidemia; hypoglycemia; maturity-onset diabetes of the young type 1; and type 2 diabetes mellitus. Orthologous to human HNF4A (hepatocyte nuclear factor 4 alpha) and HNF4G (hepatocyte nuclear factor 4 gamma). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
nhr-168
M00699_2.00
Caenorhabditis elegans
NNNHHCRNHN
NDNYGDDNNN
PBM
Narasimhan et al.(2015)
pTH10013
(Direct)
(Direct)
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
For this family, TFs with SR scores >
0.745
will likely have a similar motif
Experimental Constructs
Motif ID
Domain
From
To
Sequence
M00699_2.00
Nuclear receptor
48
119
SECSICGKTANGYHYDVPSCNGCKTFFRRLCVSEKSFICKAGGDCFNLTKRKVPLKCRACRYEKCISEGMNP
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
C50B6.8a
Nuclear receptor
48
119
SECSICGKTANGYHYDVPSCNGCKTFFRRLCVSEKSFICKAGGDCFNLTKRKVPLKCRACRYEKCISEGMNP
C50B6.8b.1
Nuclear receptor
48
119
SECSICGKTANGYHYDVPSCNGCKTFFRRLCVSEKSFICKAGGDCFNLTKRKVPLKCRACRYEKCISEGMNP
C50B6.8b.2
Nuclear receptor
48
119
SECSICGKTANGYHYDVPSCNGCKTFFRRLCVSEKSFICKAGGDCFNLTKRKVPLKCRACRYEKCISEGMNP
Links
Other
Nuclear receptor
family TFs
Other
Caenorhabditis elegans
TFs
10 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy