HEY2 (Echinops telfairi)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSETEG00000007340 T034046_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Hey2
M01722_2.00 		Mus musculus
RCACGTGNN
NNCACGTGY		 PBM
Weirauch et al.(2014)
pTH5102 		0.914 1.000
HEY2
M02790_2.00 		Homo sapiens
GRCACGTGNV
BNCACGTGYC		 SELEX
Jolma et al.(2013)
HEY2_1 		0.914 1.000
HEY2
M02791_2.00 		Homo sapiens
GVCACGTGYN
NRCACGTGBC		 SELEX
Jolma et al.(2013)
HEY2_2 		0.914 1.000
HEY2
M04131_2.00 		Homo sapiens
NVCRCGYGVN
NBCRCGYGBN		 SELEX
Yin et al.(2017)
HEY2_eDBD_HT-SELEX 		0.914 1.000
HEY2
M04133_2.00 		Homo sapiens
NVCACGTGVN
NBCACGTGBN		 SELEX
Yin et al.(2017)
HEY2_FL_HT-SELEX 		0.914 1.000
HEY2
M04132_2.00 		Homo sapiens
NVCRCGYRVN
NBYRCGYGBN		 SELEX
Yin et al.(2017)
HEY2_eDBD_Methyl-HT-SELEX 		0.914 1.000
HEY2
M04134_2.00 		Homo sapiens
NVCRCGYGSN
NSCRCGYGBN		 SELEX
Yin et al.(2017)
HEY2_FL_Methyl-HT-SELEX 		0.914 1.000
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSETEP00000005952 bHLH 49 104

Links

Other bHLH family TFs
Other Echinops telfairi TFs

163 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ACYPI000624 Acyrthosiphon pisum ACYPI000624 I
AAEL004806 Aedes aegypti AAEL004806 I
ENSAMEG00000012407 Ailuropoda melanoleuca ENSAMEG00000012407 I
ENSAMEG00000016954 Ailuropoda melanoleuca ENSAMEG00000016954 I
Alligator_sinensis_CCG013952.1 Alligator sinensis Alligator_sinensis_CCG013952.1 I
ANCDUO_04077 Ancylostoma duodenale ANCDUO_04077 I
ACAC_0001026501 Angiostrongylus cantonensis ACAC_0001026501 I
ACOC_0001313301 Angiostrongylus costaricensis ACOC_0001313301 I
KLF4 Anolis carolinensis ENSACAG00000003706 I
KLF8 Anolis carolinensis ENSACAG00000006389 I
AALB010205 Anopheles albimanus AALB010205 I
AARA000098 Anopheles arabiensis AARA000098 I
AATE020384 Anopheles atroparvus AATE020384 I
ACHR001612 Anopheles christyi ACHR001612 I
ACOM041708 Anopheles coluzzii ACOM041708 I
ACUA022835 Anopheles culicifacies ACUA022835 I
ADAC003701 Anopheles darlingi ADAC003701 I
ADIR011723 Anopheles dirus ADIR011723 I
AFAF003290 Anopheles farauti AFAF003290 I
AFUN011554 Anopheles funestus AFUN011554 I
AGAP010520 Anopheles gambiae AGAP010520 I
AMEM014876 Anopheles merus AMEM014876 I
AMIN001268 Anopheles minimus AMIN001268 I
AQUA001297 Anopheles quadriannulatus AQUA001297 I
ASTEI07110 Anopheles stephensi ASTEI07110 I
GB52090 Apis mellifera GB52090 I
Afo_R010383 Aptenodytes forsteri Afo_R010383 I
ENSAMXG00000007099 Astyanax mexicanus ENSAMXG00000007099 I
ENSAMXG00000018230 Astyanax mexicanus ENSAMXG00000018230 I
BGLB001194 Biomphalaria glabrata BGLB001194 I
BGLB007176 Biomphalaria glabrata BGLB007176 I
ENSBTAP00000043340-D1 Bos grunniens ENSBTAP00000043340-D1 I
ENSP00000326417-D1 Bos grunniens ENSP00000326417-D1 I
ENSP00000417303-D1 Bos grunniens ENSP00000417303-D1 I
KLF1 Bos taurus ENSBTAG00000006083 I
KLF4 Bos taurus ENSBTAG00000020355 I
Brh_R004702 Buceros rhinoceros Brh_R004702 I
BXY_0235800 Bursaphelenchus xylophilus BXY_0235800 I
CBN12606 Caenorhabditis brenneri CBN12606 I
CBN19589 Caenorhabditis brenneri CBN19589 I
CBG04311 Caenorhabditis briggsae CBG04311 I
klf-3 Caenorhabditis elegans WBGene00003480 D
CJA34076 Caenorhabditis japonica CJA34076 I
CRE26517 Caenorhabditis remanei CRE26517 I
KLF1 Callithrix jacchus ENSCJAG00000004762 I
KLF8 Callithrix jacchus ENSCJAG00000007304 I
KLF4 Callithrix jacchus ENSCJAG00000016955 I
Aan_R007684 Calypte anna Aan_R007684 I
KLF1 Canis familiaris ENSCAFG00000017111 I
CapteG137485 Capitella teleta CapteG137485 I
CapteG88086 Capitella teleta CapteG88086 I
KLF8 Cavia porcellus ENSCPOG00000010165 I
KLF4 Cavia porcellus ENSCPOG00000027434 I
Cmyd_10016058 Chelonia mydas Cmyd_10016058 I
ENSCSAG00000006545 Chlorocebus sabaeus ENSCSAG00000006545 I
ENSCSAG00000011429 Chlorocebus sabaeus ENSCSAG00000011429 I
ENSCSAG00000012078 Chlorocebus sabaeus ENSCSAG00000012078 I
zf(c2h2)-24 Ciona intestinalis ENSCING00000012142 I
zf(c2h2)-23 Ciona intestinalis ENSCING00000014976 I
ENSCSAVG00000002903 Ciona savignyi ENSCSAVG00000002903 I
ENSCSAVG00000006620 Ciona savignyi ENSCSAVG00000006620 I
CGI_10021556 Crassostrea gigas CGI_10021556 I
CpipJ_CPIJ004724 Culex pipiens CpipJ_CPIJ004724 I
CPIJ004724 Culex quinquefasciatus CPIJ004724 I
klf1 Danio rerio ENSDARG00000017400 I
klf8 Danio rerio ENSDARG00000060661 I
DAPPUDRAFT_27999 Daphnia pulex DAPPUDRAFT_27999 I
KLF4 Dasypus novemcinctus ENSDNOG00000043478 I
GF11307 Drosophila ananassae FBgn0088347 I
GG20076 Drosophila erecta FBgn0112270 I
GH20915 Drosophila grimshawi FBgn0128377 I
CG42741 Drosophila melanogaster FBgn0261705 D
GI18350 Drosophila mojavensis FBgn0141089 I
GL10855 Drosophila persimilis FBgn0148465 I
GA22108 Drosophila pseudoobscura FBgn0064422 I
GM15591 Drosophila sechellia FBgn0170509 I
GD25089 Drosophila simulans FBgn0196401 I
GJ20749 Drosophila virilis FBgn0207886 I
GK19604 Drosophila willistoni FBgn0221602 I
GE11614 Drosophila yakuba FBgn0229413 I
KLF4 Equus caballus ENSECAG00000010613 I
KLF8 Equus caballus ENSECAG00000016062 I
KLF8 Felis catus ENSFCAG00000012644 I
KLF1 Felis catus ENSFCAG00000026066 I
KLF4 Felis catus ENSFCAG00000028016 I
ENSFALG00000005293 Ficedula albicollis ENSFALG00000005293 I
ENSFALG00000008792 Ficedula albicollis ENSFALG00000008792 I
ENSFALG00000011267 Ficedula albicollis ENSFALG00000011267 I
ENSGMOG00000003657 Gadus morhua ENSGMOG00000003657 I
ENSGALG00000010101 Gallus gallus ENSGALG00000010101 I
KLF4 Gallus gallus ENSGALG00000026928 I
klf17 Gasterosteus aculeatus ENSGACG00000014465 I
KLF4 Gasterosteus aculeatus ENSGACG00000016540 I
Gfo_R006245 Geospiza fortis Gfo_R006245 I
KLF4 Gorilla gorilla ENSGGOG00000000096 I
KLF1 Gorilla gorilla ENSGGOG00000003408 I
KLF8 Gorilla gorilla ENSGGOG00000008188 I
HPLM_0000852701 Haemonchus placei HPLM_0000852701 I
HelroG128168 Helobdella robusta HelroG128168 I
KLF8 Homo sapiens ENSG00000102349 D
KLF1 Homo sapiens ENSG00000105610 D
KLF4 Homo sapiens ENSG00000136826 D
ENSSTOG00000012012 Ictidomys tridecemlineatus ENSSTOG00000012012 I
ENSSTOG00000022002 Ictidomys tridecemlineatus ENSSTOG00000022002 I
ISCW016565 Ixodes scapularis ISCW016565 I
ENSLACG00000004425 Latimeria chalumnae ENSLACG00000004425 I
ENSLACG00000016296 Latimeria chalumnae ENSLACG00000016296 I
ENSLOCG00000008266 Lepisosteus oculatus ENSLOCG00000008266 I
ENSLOCG00000009967 Lepisosteus oculatus ENSLOCG00000009967 I
ENSLOCG00000014956 Lepisosteus oculatus ENSLOCG00000014956 I
LotgiG111402 Lottia gigantea LotgiG111402 I
LotgiG122963 Lottia gigantea LotgiG122963 I
LotgiG179180 Lottia gigantea LotgiG179180 I
KLF4 Loxodonta africana ENSLAFG00000000421 I
KLF1 Loxodonta africana ENSLAFG00000016145 I
LCUP006184 Lucilia cuprina LCUP006184 I
ENSMMUP00000014716 Macaca fascicularis ENSMMUP00000014716 I
ENSMMUP00000019255 Macaca fascicularis ENSMMUP00000019255 I
ENSP00000326417 Macaca fascicularis ENSP00000326417 I
KLF4 Macaca mulatta ENSMMUG00000006088 I
KLF1 Macaca mulatta ENSMMUG00000011230 I
KLF1 Microcebus murinus ENSMICG00000016260 I
KLF8 Monodelphis domestica ENSMODG00000010883 I
ENSMODG00000010888 Monodelphis domestica ENSMODG00000010888 I
KLF4 Monodelphis domestica ENSMODG00000014569 I
KLF2 Monodelphis domestica ENSMODG00000014911 I
MDOA005423 Musca domestica MDOA005423 I
ENSMPUG00000004544 Mustela putorius furo ENSMPUG00000004544 I
ENSMPUG00000007236 Mustela putorius furo ENSMPUG00000007236 I
Klf4 Mus musculus ENSMUSG00000003032 D
Klf8 Mus musculus ENSMUSG00000041649 D
Myotis_brandtii_Klf4_10031585 Myotis brandtii Myotis_brandtii_Klf4_10031585 I
Myotis_brandtii_KLF8_10010984 Myotis brandtii Myotis_brandtii_KLF8_10010984 I
KLF1 Myotis lucifugus ENSMLUG00000012751 I
KLF4 Myotis lucifugus ENSMLUG00000014795 I
KLF8 Myotis lucifugus ENSMLUG00000016695 I
NV17335 Nasonia vitripennis NV17335 I
NBR_0001426101 Nippostrongylus brasiliensis NBR_0001426101 I
ENSNLEG00000012868 Nomascus leucogenys ENSNLEG00000012868 I
ENSNLEG00000016353 Nomascus leucogenys ENSNLEG00000016353 I
ENSNLEG00000017327 Nomascus leucogenys ENSNLEG00000017327 I
KLF1 Ochotona princeps ENSOPRG00000004951 I
KLF4 Ochotona princeps ENSOPRG00000005556 I
Ocbimv22019777m.g Octopus bimaculoides Ocbimv22019777m.g I
SNAPOd2T00013472001 Oikopleura dioica SNAPOd2T00013472001 I
Ogr12039 Ophisaurus gracilis Ogr12039 I
ENSONIG00000006766 Oreochromis niloticus ENSONIG00000006766 I
ENSONIG00000013257 Oreochromis niloticus ENSONIG00000013257 I
ENSONIG00000014958 Oreochromis niloticus ENSONIG00000014958 I
KLF8 Ornithorhynchus anatinus ENSOANG00000001989 I
KLF4 Ornithorhynchus anatinus ENSOANG00000004191 I
KLF8 Oryctolagus cuniculus ENSOCUG00000005068 I
ENSOCUG00000005904 Oryctolagus cuniculus ENSOCUG00000005904 I
KLF1 Oryctolagus cuniculus ENSOCUG00000011998 I
KLF4 Oryzias latipes ENSORLG00000005643 I
klf1 Oryzias latipes ENSORLG00000013713 I
klf8 Oryzias latipes ENSORLG00000015374 I
KLF1 Otolemur garnettii ENSOGAG00000025438 I
KLF4 Otolemur garnettii ENSOGAG00000029918 I
ENSOARG00000005543 Ovis aries ENSOARG00000005543 I
ENSOARG00000007169 Ovis aries ENSOARG00000007169 I
KLF1 Pan troglodytes ENSPTRG00000010547 I
KLF4 Pan troglodytes ENSPTRG00000021230 I
KLF8 Pan troglodytes ENSPTRG00000021957 I
ENSPANG00000025718 Papio anubis ENSPANG00000025718 I
PHUM236000 Pediculus humanus PHUM236000 I
ENSPSIG00000014513 Pelodiscus sinensis ENSPSIG00000014513 I
ENSPFOG00000000812 Poecilia formosa ENSPFOG00000000812 I
ENSPFOG00000010204 Poecilia formosa ENSPFOG00000010204 I
Pvit_05333 Pogona vitticeps Pvit_05333 I
Pvit_06508 Pogona vitticeps Pvit_06508 I
Pvit_14591 Pogona vitticeps Pvit_14591 I
ENSPPYG00000009612 Pongo abelii ENSPPYG00000009612 I
ENSPPYG00000019478 Pongo abelii ENSPPYG00000019478 I
ENSPPYG00000020400 Pongo abelii ENSPPYG00000020400 I
KLF4 Procavia capensis ENSPCAG00000011130 I
KLF1 Procavia capensis ENSPCAG00000015589 I
KLF8 Pteropus vampyrus ENSPVAG00000000264 I
KLF4 Pteropus vampyrus ENSPVAG00000001093 I
Klf4 Rattus norvegicus ENSRNOG00000016299 I
Klf8 Rattus norvegicus ENSRNOG00000039057 I
Sakowv30017238m.g Saccoglossus kowalevskii Sakowv30017238m.g I
Sakowv30017457m.g Saccoglossus kowalevskii Sakowv30017457m.g I
ENSSHAG00000002694 Sarcophilus harrisii ENSSHAG00000002694 I
ENSSHAG00000013106 Sarcophilus harrisii ENSSHAG00000013106 I
KLF8 Sorex araneus ENSSARG00000013181 I
L889_g30961 Steinernema feltiae L889_g30961 I
L893_g29274 Steinernema glaseri L893_g29274 I
L898_g19820 Steinernema monticolum L898_g19820 I
L892_g18702 Steinernema scapterisci L892_g18702 I
SPU_017470 Strongylocentrotus purpuratus SPU_017470 I
SPU_020311 Strongylocentrotus purpuratus SPU_020311 I
ENSSSCG00000005437 Sus scrofa ENSSSCG00000005437 I
KLF1 Sus scrofa ENSSSCG00000013730 I
ENSTGUG00000005539 Taeniopygia guttata ENSTGUG00000005539 I
ENSTRUG00000007828 Takifugu rubripes ENSTRUG00000007828 I
KLF4 Takifugu rubripes ENSTRUG00000009613 I
klf8 Takifugu rubripes ENSTRUG00000009714 I
ENSTSYG00000011477 Tarsius syrichta ENSTSYG00000011477 I
tetur04g03720 Tetranychus urticae tetur04g03720 I
tetur17g00210 Tetranychus urticae tetur17g00210 I
klf8 Tetraodon nigroviridis ENSTNIG00000004690 I
KLF4 Tetraodon nigroviridis ENSTNIG00000019371 I
TC006126 Tribolium castaneum TC006126 I
EFV55190 Trichinella spiralis EFV55190 I
EFV55215 Trichinella spiralis EFV55215 I
D918_01816 Trichuris suis D918_01816 I
D918_06264 Trichuris suis D918_06264 I
TTRE_0000268201 Trichuris trichiura TTRE_0000268201 I
KLF1 Tupaia belangeri ENSTBEG00000013433 I
KLF8 Tursiops truncatus ENSTTRG00000008773 I
KLF4 Vicugna pacos ENSVPAG00000004645 I
klf8.L Xenopus laevis XB-GENE-1021778 I
klf8 Xenopus tropicalis XB-GENE-1021774 I
ENSXMAG00000014131 Xiphophorus maculatus ENSXMAG00000014131 I
L798_10335 Zootermopsis nevadensis L798_10335 I