AFUN005050 (Anopheles funestus)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00010 (HLH) IPR001092 AFUN005050 T052775_2.00 Vectorbase (2015-Oct-22)

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
HLH4C
M03609_2.00 		Drosophila melanogaster
DDNCRCAGCTGYGNHH
DDNCRCAGCTGYGNHH		 SELEX
Nitta et al.(2015)
HLH4C_1 		0.911 0.942
HLH4C
M03610_2.00 		Drosophila melanogaster
DRSMYCAGCTGVKSYH
DRSMBCAGCTGRKSYH		 SELEX
Nitta et al.(2015)
HLH4C_2 		0.911 0.942
HLH4C
M03611_2.00 		Drosophila melanogaster
NRBMYCAGCTGYGNHH
DDNCRCAGCTGRKVYN		 SELEX
Nitta et al.(2015)
HLH4C_3 		0.911 0.942
HLH4C
M05963_2.00 		Drosophila melanogaster
CACCTGMDCC
GGHKCAGGTG		 B1H
Zhu et al.(2011)
HLH4C_da_SANGER_5_3_FBgn0011277 		0.911 0.942
HLH4C
M05964_2.00 		Drosophila melanogaster
MCAYCTGMGMMM
KKKCKCAGRTGK		 B1H
Zhu et al.(2011)
HLH4C_da_SANGER_5_4_FBgn0011277 		0.911 0.942
HLH4C
M05965_2.00 		Drosophila melanogaster
VNHHVCACCTGMBNC
GNVKCAGGTGBDDNB		 B1H
Zhu et al.(2011)
HLH4C_da_SANGER_5_FBgn0011277 		0.911 0.942
HLH4C
M05966_2.00 		Drosophila melanogaster
RGSMYCAGCTGCGYY
RRCGCAGCTGRKSCY		 B1H
Zhu et al.(2011)
HLH4C_SANGER_5_FBgn0011277 		0.911 0.942
NHLH1
M02796_2.00 		Homo sapiens
CGCAGCTGCB
VGCAGCTGCG		 SELEX
Jolma et al.(2013)
NHLH1_1 		0.894 0.942
NHLH1
M02797_2.00 		Homo sapiens
VGCAGCTGCK
MGCAGCTGCB		 SELEX
Jolma et al.(2013)
NHLH1_2 		0.894 0.942
NHLH1
M04162_2.00 		Homo sapiens
NDGNMKCAGCTGCGYCMH
DKGRCGCAGCTGMKNCHN		 SELEX
Yin et al.(2017)
NHLH1_eDBD_HT-SELEX 		0.894 0.942
NHLH1
M04164_2.00 		Homo sapiens
NDGNMKCAGCTGCGYCMH
DKGRCGCAGCTGMKNCHN		 SELEX
Yin et al.(2017)
NHLH1_FL_HT-SELEX 		0.894 0.942
Nhlh1
M08773_2.00 		Mus musculus
BKGGNMNCAGCTGCGBCCYY
RRGGVCGCAGCTGNKNCCMV		 Misc
Kulakovskiy et al.(2013)
HEN1_MOUSE.H11MO.0.C 		0.894 0.942
NHLH1
M09875_2.00 		Homo sapiens
NNDGGNMVCAGCTGVGNCCNNN
NNNGGNCBCAGCTGBKNCCHNN		 Transfac
Matys et al.(2006)
V$HEN1_01 		0.894 0.942
NHLH1
M09876_2.00 		Homo sapiens
NDRGGVMGCAGCTGMKNCCHHN
NDDGGNMKCAGCTGCKBCCYHN		 Transfac
Matys et al.(2006)
V$HEN1_02 		0.894 0.942
NHLH1
M04163_2.00 		Homo sapiens
NRGBMKCAGCTGCGYCCH
DGGRCGCAGCTGMKVCYN		 SELEX
Yin et al.(2017)
NHLH1_eDBD_Methyl-HT-SELEX 		0.894 0.942
NHLH1
M04165_2.00 		Homo sapiens
DGGNMBCAGCTGCGYCCH
DGGRCGCAGCTGVKNCCH		 SELEX
Yin et al.(2017)
NHLH1_FL_Methyl-HT-SELEX 		0.894 0.942
Nhlh2
M00756_2.00 		Mus musculus
NKCAGCTGHN
NDCAGCTGMN		 PBM
Weirauch et al.(2013)
pTH3037 		0.894 0.923
NHLH2
M04177_2.00 		Homo sapiens
DDGNMGCAGCTGCGYCMH
DKGRCGCAGCTGCKNCHH		 SELEX
Yin et al.(2017)
NHLH2_FL_HT-SELEX 		0.894 0.923
NHLH2
M09878_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HEN2_Q2 		0.894 0.923
NHLH2
M04178_2.00 		Homo sapiens
DGGNMBCAGCTGCGYCCH
DGGRCGCAGCTGVKNCCH		 SELEX
Yin et al.(2017)
NHLH2_FL_Methyl-HT-SELEX 		0.894 0.923
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
AFUN005050-PA bHLH 83 135

Links

Other bHLH family TFs
Other Anopheles funestus TFs

168 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ACYPI55143 Acyrthosiphon pisum ACYPI55143 I 0.000
AAEL000041 Aedes aegypti AAEL000041 I 0.000
AAEL015632 Aedes aegypti AAEL015632 I 0.000
ENSAMEG00000010217 Ailuropoda melanoleuca ENSAMEG00000010217 I 0.000
Alligator_sinensis_CCG012275.1 Alligator sinensis Alligator_sinensis_CCG012275.1 I 0.000
ENSAPLG00000003960 Anas platyrhynchos ENSAPLG00000003960 I 0.000
ENSACAG00000004870 Anolis carolinensis ENSACAG00000004870 I 0.000
FOXJ1 Anolis carolinensis ENSACAG00000008123 I 0.000
AALB009484 Anopheles albimanus AALB009484 I 0.000
AARA004720 Anopheles arabiensis AARA004720 I 0.000
AATE008326 Anopheles atroparvus AATE008326 I 0.000
ACHR000066 Anopheles christyi ACHR000066 I 0.000
ACOM037496 Anopheles coluzzii ACOM037496 I 0.000
ACUA019142 Anopheles culicifacies ACUA019142 I 0.000
ADIR002760 Anopheles dirus ADIR002760 I 0.000
AEPI002386 Anopheles epiroticus AEPI002386 I 0.000
AFAF012594 Anopheles farauti AFAF012594 I 0.000
AFUN009863 Anopheles funestus AFUN009863 I 0.000
AGAP002903 Anopheles gambiae AGAP002903 I 0.000
AMEC017755 Anopheles melas AMEC017755 I 0.000
AMEM004834 Anopheles merus AMEM004834 I 0.000
AMIN000724 Anopheles minimus AMIN000724 I 0.000
AQUA009304 Anopheles quadriannulatus AQUA009304 I 0.000
ASTEI00078 Anopheles stephensi ASTEI00078 I 0.000
GB50277 Apis mellifera GB50277 I 0.000
Afo_R006429 Aptenodytes forsteri Afo_R006429 I 0.000
ENSAMXG00000006564 Astyanax mexicanus ENSAMXG00000006564 I 0.000
ACEP22192 Atta cephalotes ACEP22192 I 0.000
BGLB014205 Biomphalaria glabrata BGLB014205 I 0.000
BGIBMGA005669 Bombyx mori BGIBMGA005669 I 0.000
ENSP00000323880-D1 Bos grunniens ENSP00000323880-D1 I 0.000
FOXJ1 Bos taurus ENSBTAG00000007916 I 0.000
estExt_fgenesh2_pg.C_170078 Branchiostoma floridae estExt_fgenesh2_pg.C_170078 I 0.000
FOXJ1 Callithrix jacchus ENSCJAG00000013682 I 0.000
Aan_R012851 Calypte anna Aan_R012851 I 0.000
Cflo_07076--XP_623740.2_APIME Camponotus floridanus Cflo_07076--XP_623740.2_APIME I 0.000
FOXJ1 Canis familiaris ENSCAFG00000005050 I 0.000
CapteG222987 Capitella teleta CapteG222987 I 0.000
ENSCPOG00000010965 Cavia porcellus ENSCPOG00000010965 I 0.000
Cmyd_10016658 Chelonia mydas Cmyd_10016658 I 0.000
ENSCSAG00000004998 Chlorocebus sabaeus ENSCSAG00000004998 I 0.000
CLEC000256 Cimex lectularius CLEC000256 I 0.000
csin105476 Clonorchis sinensis csin105476 I 0.000
CGI_10021832 Crassostrea gigas CGI_10021832 I 0.000
CpipJ_CPIJ016958 Culex pipiens CpipJ_CPIJ016958 I 0.000
CPIJ016958 Culex quinquefasciatus CPIJ016958 I 0.000
foxj1b Danio rerio ENSDARG00000088290 I 0.000
foxj1a Danio rerio ENSDARG00000101919 I 0.000
DAPPUDRAFT_8603 Daphnia pulex DAPPUDRAFT_8603 I 0.000
FOXJ1 Dasypus novemcinctus ENSDNOG00000036643 I 0.000
DILT_0000300801 Diphyllobothrium latum DILT_0000300801 I 0.000
ECANG7_05018 Echinococcus canadensis ECANG7_05018 I 0.000
EmuJ_000660100 Echinococcus multilocularis EmuJ_000660100 I 0.000
EEL_0000828301 Elaeophora elaphi EEL_0000828301 N 0.000
FOXJ1 Equus caballus ENSECAG00000014390 I 0.000
FOXJ1 Felis catus ENSFCAG00000005772 I 0.000
ENSFALG00000000971 Ficedula albicollis ENSFALG00000000971 I 0.000
ENSGMOG00000015882 Gadus morhua ENSGMOG00000015882 I 0.000
foxj1b Gasterosteus aculeatus ENSGACG00000004462 I 0.000
foxj1a Gasterosteus aculeatus ENSGACG00000014879 I 0.000
Gfo_R007395 Geospiza fortis Gfo_R007395 I 0.000
GPUH_0001233401 Gongylonema pulchrum GPUH_0001233401 N 0.000
FOXJ1 Gorilla gorilla ENSGGOG00000007282 I 0.000
Hsal_04799--XP_623740.2_APIME Harpegnathos saltator Hsal_04799--XP_623740.2_APIME I 0.000
HMEL002016 Heliconius melpomene HMEL002016 I 0.000
FOXJ1 Homo sapiens ENSG00000129654 D 0.000
TTAC_0000110701 Hydatigera taeniaeformis TTAC_0000110701 I 0.000
XP_002158068.1 Hydra magnipapillata XP_002158068.1 I 0.000
HDID_0000845501 Hymenolepis diminuta HDID_0000845501 I 0.000
HmN_000875600 Hymenolepis microstoma HmN_000875600 I 0.000
HNAJ_0000187001 Hymenolepis nana HNAJ_0000187001 I 0.000
ENSSTOG00000021584 Ictidomys tridecemlineatus ENSSTOG00000021584 I 0.000
ISCW018243 Ixodes scapularis ISCW018243 I 0.000
ENSLACG00000016329 Latimeria chalumnae ENSLACG00000016329 I 0.000
ENSLACG00000016929 Latimeria chalumnae ENSLACG00000016929 I 0.000
ENSLOCG00000011207 Lepisosteus oculatus ENSLOCG00000011207 I 0.000
LDEC013372 Leptinotarsa decemlineata LDEC013372 I 0.000
nLs.2.1.2.g08818 Litomosoides sigmodontis nLs.2.1.2.g08818 N 0.000
LOAG_18956 Loa loa LOAG_18956 N 0.000
LotgiG69660 Lottia gigantea LotgiG69660 I 0.000
FOXJ1 Loxodonta africana ENSLAFG00000032043 I 0.000
FOXJ1 Macaca mulatta ENSMMUG00000003533 I 0.000
ENSMEUG00000007843 Macropus eugenii ENSMEUG00000007843 I 0.000
FOXJ1 Meleagris gallopavo ENSMGAG00000004252 I 0.000
MCINX001888 Melitaea cinxia MCINX001888 I 0.000
ENSMICG00000013240 Microcebus murinus ENSMICG00000013240 I 0.000
FOXJ1 Monodelphis domestica ENSMODG00000008306 I 0.000
ENSMPUG00000013521 Mustela putorius furo ENSMPUG00000013521 I 0.000
Foxj1 Mus musculus ENSMUSG00000034227 D 0.000
FOXJ1 Myotis lucifugus ENSMLUG00000006595 I 0.000
NEMVEDRAFT_v1g65438 Nematostella vectensis NEMVEDRAFT_v1g65438 I 0.000
FOXJ1 Ochotona princeps ENSOPRG00000011410 I 0.000
Ocbimv22006019m.g Octopus bimaculoides Ocbimv22006019m.g I 0.000
OFLC_0000364301 Onchocerca flexuosa OFLC_0000364301 N 0.000
nOo.2.0.1.g09031 Onchocerca ochengi nOo.2.0.1.g09031 N 0.000
WBGene00242350 Onchocerca volvulus WBGene00242350 N 0.000
Ogr05152 Ophisaurus gracilis Ogr05152 I 0.000
Ogr16080 Ophisaurus gracilis Ogr16080 I 0.000
T265_06415 Opisthorchis viverrini T265_06415 I 0.000
ENSONIG00000009418 Oreochromis niloticus ENSONIG00000009418 I 0.000
ENSONIG00000019769 Oreochromis niloticus ENSONIG00000019769 I 0.000
FOXJ1 Ornithorhynchus anatinus ENSOANG00000014384 I 0.000
FOXJ1 Oryctolagus cuniculus ENSOCUG00000011472 I 0.000
FOXJ1 Otolemur garnettii ENSOGAG00000026625 I 0.000
ENSOARG00000007895 Ovis aries ENSOARG00000007895 I 0.000
FOXJ1 Pan troglodytes ENSPTRG00000009674 I 0.000
ENSPANG00000020054 Papio anubis ENSPANG00000020054 I 0.000
PHUM083480 Pediculus humanus PHUM083480 I 0.000
ENSPSIG00000002424 Pelodiscus sinensis ENSPSIG00000002424 I 0.000
ENSPMAG00000005958 Petromyzon marinus ENSPMAG00000005958 I 0.000
ENSPMAG00000006623 Petromyzon marinus ENSPMAG00000006623 I 0.000
ENSPFOG00000004597 Poecilia formosa ENSPFOG00000004597 I 0.000
ENSPFOG00000019618 Poecilia formosa ENSPFOG00000019618 I 0.000
Pvit_10306 Pogona vitticeps Pvit_10306 I 0.000
ENSPPYG00000008652 Pongo abelii ENSPPYG00000008652 I 0.000
FOXJ1 Procavia capensis ENSPCAG00000015387 I 0.000
nRc.2.0.1.g07784 Romanomermis culicivorax nRc.2.0.1.g07784 N 0.000
Sakowv30028437m.g Saccoglossus kowalevskii Sakowv30028437m.g I 0.000
PTSG_00936 Salpingoeca rosetta PTSG_00936 N 0.000
ENSSHAG00000017120 Sarcophilus harrisii ENSSHAG00000017120 I 0.000
A_01406 Schistosoma haematobium A_01406 I 0.000
SMU15026964 Schmidtea mediterranea SMU15026964 I 0.000
SMU15031994 Schmidtea mediterranea SMU15031994 I 0.000
SMU15036325 Schmidtea mediterranea SMU15036325 I 0.000
SINV20866 Solenopsis invicta SINV20866 I 0.000
SMAR007498 Strigamia maritima SMAR007498 I 0.000
SPU_027969 Strongylocentrotus purpuratus SPU_027969 I 0.000
FOXJ1 Sus scrofa ENSSSCG00000017187 I 0.000
TsM_000185900 Taenia solium TsM_000185900 I 0.000
FOXJ1 Taeniopygia guttata ENSTGUG00000008019 I 0.000
foxj1a Takifugu rubripes ENSTRUG00000001697 I 0.000
foxj1b Takifugu rubripes ENSTRUG00000016940 I 0.000
foxj1a Tetraodon nigroviridis ENSTNIG00000011308 I 0.000
foxj1b Tetraodon nigroviridis ENSTNIG00000012916 I 0.000
TC005573 Tribolium castaneum TC005573 I 0.000
D917_09696 Trichinella nativa D917_09696 N 0.000
EFV62115 Trichinella spiralis EFV62115 N 0.000
TriadG17444 Trichoplax adhaerens TriadG17444 I 0.000
TMUE_s0025000400 Trichuris muris TMUE_s0025000400 N 0.000
D918_08586 Trichuris suis D918_08586 N 0.000
TTRE_0000137701 Trichuris trichiura TTRE_0000137701 N 0.000
FOXJ1 Tursiops truncatus ENSTTRG00000015916 I 0.000
Tal_R007079 Tyto alba Tal_R007079 I 0.000
foxj1.S Xenopus laevis XB-GENE-6254646 I 0.000
foxj1.L Xenopus laevis XB-GENE-856300 I 0.000
foxj1.2.L Xenopus laevis XB-GENE-919747 I 0.000
foxj1 Xenopus tropicalis XB-GENE-853648 I 0.000
foxj1.2 Xenopus tropicalis XB-GENE-919738 I 0.000
L798_14003 Zootermopsis nevadensis L798_14003 I 0.000