gem (Drosophila melanogaster)
Grainyhead

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF04516 (CP2) IPR007604 FBgn0050011 T199302_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including embryonic/larval gut; extended germ band embryo; presumptive embryonic/larval system; wing disc; and yolk nucleus. Orthologous to several human genes including TFCP2 (transcription factor CP2) and TFCP2L1 (transcription factor CP2 like 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
gem
M03769_2.00		 Drosophila melanogaster
DAACYRGTTHDAACYRGWTH
DAWCYRGTTHDAACYRGTTH		 SELEX
Nitta et al.(2015)
gem_1		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
FBpp0088699 Grainyhead 373 563
FBpp0088699 Grainyhead 582 627
FBpp0088700 Grainyhead 360 550
FBpp0088700 Grainyhead 569 614
FBpp0312214 Grainyhead 360 550
FBpp0312214 Grainyhead 569 614

Links

Other Grainyhead family TFs
Other Drosophila melanogaster TFs

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14 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action