CDX2 (Homo sapiens)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSG00000165556 T209886_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
CDX2
M03196_2.00		 Homo sapiens
KTTTATKRB
VYMATAAAM		 SELEX
Jolma et al.(2013)
CDX2_1		 (Direct) (Direct)
CDX2
M05248_2.00		 Homo sapiens
NDTWAYRRYN
NRYYRTWAHN		 SELEX
Yin et al.(2017)
CDX2_eDBD_HT-SELEX_1		 (Direct) (Direct)
CDX2
M05249_2.00		 Homo sapiens
NDWWATKRB
VYMATWWHN		 SELEX
Yin et al.(2017)
CDX2_eDBD_HT-SELEX_2		 (Direct) (Direct)
CDX2
M05250_2.00		 Homo sapiens
NRTCGTAWHBNN
NNVDWTACGAYN		 SELEX
Yin et al.(2017)
CDX2_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)
CDX2
M08131_2.00		 Homo sapiens
YTTTATKRCHB
VDGYMATAAAR		 ChIP-seq
Mathelier et al.(2014)
MA0465.1		 (Direct) (Direct)
CDX2
M09152_2.00		 Homo sapiens
DTTBATKGCHNB
VNDGCMATVAAH		 Misc
Kulakovskiy et al.(2013)
CDX2_HUMAN.H11MO.0.A		 (Direct) (Direct)
CDX2
M10723_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CDX2_Q5_01		 (Direct) (Direct)
CDX2
M10724_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CDX2_Q5_02		 (Direct) (Direct)
CDX2
M10725_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CDX2_Q5		 (Direct) (Direct)
CDX2
M10726_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CDX2_Q6		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Cdx2
M00447_2.00 		Mus musculus
NWWAYDRNN
NNYHRTWWN		 PBM
Berger et al.(2008)
Cdx2_4272 		0.862 0.965
Cdx2
M09193_2.00 		Mus musculus
BTTTATKRCYBY
RVRGYMATAAAV		 Misc
Kulakovskiy et al.(2013)
CDX2_MOUSE.H11MO.0.A 		0.862 0.965
Cdx2
M09572_2.00 		Mus musculus
NTTTTATKRC
GYMATAAAAN		 Misc
Heinz et al.(2010)
mES-Cdx2_GSE14586 		0.862 0.965
CDX1
M10761_2.00 		Gallus gallus
BDBWAAK
MTTWVHV		 Transfac
Matys et al.(2006)
V$CDXA_01 		0.855 0.965
CDX1
M10762_2.00 		Gallus gallus
WWWWMYR
YRKWAWW		 Transfac
Matys et al.(2006)
V$CDXA_02 		0.855 0.965
Cdx1
M00427_2.00 		Mus musculus
NWWATDRNN
NNYHATWWN		 PBM
Berger et al.(2008)
Cdx1_2245 		0.855 0.947
CDX1
M03115_2.00 		Homo sapiens
NTTTATKRB
VYMATAAAN		 SELEX
Jolma et al.(2013)
CDX1_1 		0.855 0.947
CDX1
M05018_2.00 		Homo sapiens
VKTTTATKRCN
NGYMATAAAMB		 SELEX
Yin et al.(2017)
CDX1_eDBD_HT-SELEX 		0.855 0.947
CDX1
M09140_2.00 		Homo sapiens
HCWTAAAD
HTTTAWGD		 Misc
Kulakovskiy et al.(2013)
CDX1_HUMAN.H11MO.0.C 		0.855 0.947
Cdx1
M09186_2.00 		Mus musculus
HCWTAAAD
HTTTAWGD		 Misc
Kulakovskiy et al.(2013)
CDX1_MOUSE.H11MO.0.C 		0.855 0.947
CDX1
M10670_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CDX1_Q4 		0.855 0.947
CDX1
M10671_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CDX1_Q5 		0.855 0.947
CDX1
M05019_2.00 		Homo sapiens
NGTCGTAAAWB
VWTTTACGACN		 SELEX
Yin et al.(2017)
CDX1_eDBD_Methyl-HT-SELEX 		0.855 0.947
cad
M03780_2.00 		Drosophila melanogaster
NKTTTATKRCHB
VDGYMATAAAMN		 SELEX
Nitta et al.(2015)
cad_1 		0.851 0.877
cad
M03781_2.00 		Drosophila melanogaster
NDTTTATKRCHN
NDGYMATAAAHN		 SELEX
Nitta et al.(2015)
cad_2 		0.851 0.877
cad
M03782_2.00 		Drosophila melanogaster
NDTTTATKRCNB
VNGYMATAAAHN		 SELEX
Nitta et al.(2015)
cad_3 		0.851 0.877
cad
M03783_2.00 		Drosophila melanogaster
NNTTTAYGRYNN
NNRYCRTAAANN		 SELEX
Nitta et al.(2015)
cad_4 		0.851 0.877
cad
M06223_2.00 		Drosophila melanogaster
HTTWATTR
YAATWAAD		 B1H
Zhu et al.(2011)
Cad_Cell_FBgn0000251 		0.851 0.877
cad
M06224_2.00 		Drosophila melanogaster
RBYVDAAMV
BKTTHBRVY		 B1H
Zhu et al.(2011)
cad_FlyReg_FBgn0000251 		0.851 0.877
cad
M06225_2.00 		Drosophila melanogaster
NTTWATKR
YMATWAAN		 B1H
Zhu et al.(2011)
Cad_SOLEXA_FBgn0000251 		0.851 0.877
cad
M08420_2.00 		Drosophila melanogaster
DTTTTATKRYY
RRYMATAAAAH		 ChIP-chip
Mathelier et al.(2014)
MA0216.2 		0.851 0.877
cad
M09580_2.00 		Drosophila melanogaster
DTTTAYGRYN
NRYCRTAAAH		 Misc
Heinz et al.(2010)
Drosophila-Embryos_modEncode 		0.851 0.877
cad
M09674_2.00 		Drosophila melanogaster
HTTTATKRBY
RVYMATAAAD		 Misc
Kulakovskiy et al.(2009)
cad 		0.851 0.877
cad
M10783_2.00 		Drosophila melanogaster Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
I$CAD_Q6 		0.851 0.877
Q70LF3_ARTSF
M02211_2.00 		Artemia franciscana
BTAATTAB
VTAATTAV		 PBM
Weirauch et al.(2014)
pTH5553 		0.834 0.895
Cdx4
M09197_2.00 		Mus musculus
WGATTTATDRBH
DVYHATAAATCW		 Misc
Kulakovskiy et al.(2013)
CDX4_MOUSE.H11MO.0.A 		0.819 0.895
CDX4
M05129_2.00 		Homo sapiens
VKTTTATKRCH
DGYMATAAAMB		 SELEX
Yin et al.(2017)
CDX4_FL_HT-SELEX 		0.819 0.877
CDX4
M05130_2.00 		Homo sapiens
BGTCGTAAAHN
NDTTTACGACV		 SELEX
Yin et al.(2017)
CDX4_FL_Methyl-HT-SELEX_1 		0.819 0.877
CDX4
M05131_2.00 		Homo sapiens
VKTTTATKGCN
NGCMATAAAMB		 SELEX
Yin et al.(2017)
CDX4_FL_Methyl-HT-SELEX_2 		0.819 0.877
pal-1
M02183_2.00 		Caenorhabditis elegans
GYAATWAA
TTWATTRC		 PBM
Weirauch et al.(2014)
pTH6016 		0.650 0.684
Q9GP48_9TURB
M02217_2.00 		Discocelis tigrina
DTAATTAB
VTAATTAH		 PBM
Weirauch et al.(2014)
pTH6515 		0.641 0.702
Q24782_9CNID
M02206_2.00 		Eleutheria dichotoma
TTAATTAA
TTAATTAA		 PBM
Weirauch et al.(2014)
pTH5486 		0.613 0.561
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000370408 Homeodomain 187 243

Links

Other Homeodomain family TFs
Other Homo sapiens TFs

346 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
Aquca_014_00805 Aquilegia coerulea Aquca_014_00805 N 0.000
SIGD Arabidopsis thaliana AT5G13730 N 0.000
Bostr.2902s0107 Boechera stricta Bostr.2902s0107 N 0.000
Bo2g011520 Brassica oleracea Bo2g011520 N 0.000
Bo9g166510 Brassica oleracea Bo9g166510 N 0.000
Bra023430 Brassica rapa Bra023430 N 0.000
Bra008807 Brassica rapa Bra008807 N 0.000
Cagra.0596s0063 Capsella grandiflora Cagra.0596s0063 N 0.000
Carubv10001054m.g Capsella rubella Carubv10001054m.g N 0.000
evm.TU.supercontig_125.39 Carica papaya evm.TU.supercontig_125.39 N 0.000
Ciclev10033747m.g Citrus clementina Ciclev10033747m.g N 0.000
orange1.1g046578m.g Citrus sinensis orange1.1g046578m.g N 0.000
Cucsa.248920 Cucumis sativus Cucsa.248920 N 0.000
Thhalv10013654m.g Eutrema salsugineum Thhalv10013654m.g N 0.000
gene29494-v1.0-hybrid Fragaria vesca gene29494-v1.0-hybrid N 0.000
MDP0000266956 Malus domestica MDP0000266956 N 0.000
MDP0000235160 Malus domestica MDP0000235160 N 0.000
mgf003626m Mimulus guttatus mgf003626m N 0.000
PDK_20s1385451g001 Phoenix dactylifera PDK_20s1385451g001 N 0.000
Pm016510 Prunus mume Pm016510 N 0.000
PRUPE_ppa017025mg Prunus persica PRUPE_ppa017025mg N 0.000
PGSC0003DMG402006783 Solanum tuberosum PGSC0003DMG402006783 N 0.000
SIG4 Vitis vinifera VIT_13s0064g00190 N 0.000