six4a (Takifugu rubripes)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSTRUG00000010704 T216727_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Six4
M00461_2.00 		Mus musculus
NNKABMHNN
NNDKVTMNN		 PBM
Berger et al.(2008)
Six4_2860 		0.866 0.906
SIX4
M04939_2.00 		Homo sapiens
NVYGATACVB
VBGTATCRBN		 SELEX
Yin et al.(2017)
SIX4_eDBD_HT-SELEX 		0.866 0.906
Six4
M09198_2.00 		Mus musculus
DGDAABHNSASNNN
NNNSTSNDVTTHCH		 Misc
Kulakovskiy et al.(2013)
SIX4_MOUSE.H11MO.0.C 		0.866 0.906
SIX4
M10646_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SIX4_Q3 		0.866 0.906
SIX4
M04940_2.00 		Homo sapiens
NBGTAWCRHN
NDYGWTACVN		 SELEX
Yin et al.(2017)
SIX4_eDBD_Methyl-HT-SELEX 		0.866 0.906
Six4
M00563_2.00 		Drosophila melanogaster
NNDANMHNN
NNDKNTHNN		 PBM
Busser et al.(2012a)
Six4 		0.827 0.792
Six4
M06530_2.00 		Drosophila melanogaster
TGABAC
GTVTCA		 B1H
Mathelier et al.(2014)
MA0204.1 		0.827 0.792
Six4
M06334_2.00 		Drosophila melanogaster
WDDTGABAC
GTVTCAHHW		 B1H
Zhu et al.(2011)
Six4_Cell_FBgn0027364 		0.827 0.792
Six4
M06335_2.00 		Drosophila melanogaster
NTGAKACB
VGTMTCAN		 B1H
Zhu et al.(2011)
Six4_SOLEXA_2_FBgn0027364 		0.827 0.792
Six4
M06336_2.00 		Drosophila melanogaster
NNNTGABA
TVTCANNN		 B1H
Zhu et al.(2011)
Six4_SOLEXA_FBgn0027364 		0.827 0.792
SIX5
M08208_2.00 		Homo sapiens
GARWTGTAGT
ACTACAWYTC		 ChIP-seq
Contrino et al.(2012)
Mv121 		0.826 0.792
SIX5
M08209_2.00 		Homo sapiens
GGAGTTGT
ACAACTCC		 ChIP-seq
Contrino et al.(2012)
Mv123 		0.826 0.792
SIX5
M10738_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SIX5_01 		0.826 0.792
SIX5
M10739_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SIX5_02 		0.826 0.792
so
M02117_2.00 		Drosophila melanogaster
NDATMYNNN
NNNRKATHN		 PBM
Weirauch et al.(2014)
pTH5690 		0.708 0.717
so
M03800_2.00 		Drosophila melanogaster
NYGATAYB
VRTATCRN		 SELEX
Nitta et al.(2015)
so_1 		0.708 0.717
so
M03801_2.00 		Drosophila melanogaster
YKATAYNNNYGATAY
RTATCRNNNRTATMR		 SELEX
Nitta et al.(2015)
so_2 		0.708 0.717
so
M03802_2.00 		Drosophila melanogaster
YGATACGTATCR
YGATACGTATCR		 SELEX
Nitta et al.(2015)
so_3 		0.708 0.717
so
M03803_2.00 		Drosophila melanogaster
RTATCRYGATAC
GTATCRYGATAY		 SELEX
Nitta et al.(2015)
so_4 		0.708 0.717
so
M06497_2.00 		Drosophila melanogaster
TGATAC
GTATCA		 B1H
Mathelier et al.(2014)
MA0246.1 		0.708 0.717
so
M06268_2.00 		Drosophila melanogaster
NRTGATA
TATCAYN		 B1H
Zhu et al.(2011)
So_Cell_FBgn0003460 		0.708 0.717
so
M06269_2.00 		Drosophila melanogaster
NNNTGATA
TATCANNN		 B1H
Zhu et al.(2011)
So_SOLEXA_FBgn0003460 		0.708 0.717
Six2
M00425_2.00 		Mus musculus
NNAYMYNN
NNRKRTNN		 PBM
Berger et al.(2008)
Six2_2307 		0.708 0.698
Six1
M00512_2.00 		Mus musculus
NNDATMYNNN
NNNRKATHNN		 PBM
Berger et al.(2008)
Six1_0935 		0.708 0.698
SIX1
M05094_2.00 		Homo sapiens
NNYGATACVB
VBGTATCRNN		 SELEX
Yin et al.(2017)
SIX1_eDBD_HT-SELEX 		0.708 0.698
SIX1
M05096_2.00 		Homo sapiens
NNYGATAYVB
VBRTATCRNN		 SELEX
Yin et al.(2017)
SIX1_FL_HT-SELEX 		0.708 0.698
SIX2
M05285_2.00 		Homo sapiens
NNYGATACSB
VSGTATCRNN		 SELEX
Yin et al.(2017)
SIX2_eDBD_HT-SELEX 		0.708 0.698
SIX2
M05287_2.00 		Homo sapiens
NSGTRWCRYN
NRYGWYACSN		 SELEX
Yin et al.(2017)
SIX2_FL_HT-SELEX 		0.708 0.698
SIX1
M08130_2.00 		Homo sapiens
GWAACCTGANM
KNTCAGGTTWC		 ChIP-seq
Mathelier et al.(2014)
MA1118.1 		0.708 0.698
SIX2
M08133_2.00 		Homo sapiens
NNNTGWAACCTGAKMH
DKMTCAGGTTWCANNN		 ChIP-seq
Mathelier et al.(2014)
MA1119.1 		0.708 0.698
SIX1
M09142_2.00 		Homo sapiens
DGWAAYHTGABMYN
NRKVTCADRTTWCH		 Misc
Kulakovskiy et al.(2013)
SIX1_HUMAN.H11MO.0.A 		0.708 0.698
SIX2
M09157_2.00 		Homo sapiens
DGWAAYHHGABMH
DKVTCDDRTTWCH		 Misc
Kulakovskiy et al.(2013)
SIX2_HUMAN.H11MO.0.A 		0.708 0.698
Six2
M09185_2.00 		Mus musculus
DGWAAYHYRABMYB
VRKVTYRDRTTWCH		 Misc
Kulakovskiy et al.(2013)
SIX2_MOUSE.H11MO.0.A 		0.708 0.698
Six1
M09579_2.00 		Mus musculus
GWAAYHTGABMH
DKVTCADRTTWC		 Misc
Heinz et al.(2010)
Myoblast-Six1_GSE20150 		0.708 0.698
SIX1
M10684_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SIX1_Q3_01 		0.708 0.698
SIX1
M10685_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SIX1_Q3 		0.708 0.698
SIX1
M05095_2.00 		Homo sapiens
NNYGATABNB
VNVTATCRNN		 SELEX
Yin et al.(2017)
SIX1_eDBD_Methyl-HT-SELEX 		0.708 0.698
SIX1
M05097_2.00 		Homo sapiens
NNYGATAYSB
VSRTATCRNN		 SELEX
Yin et al.(2017)
SIX1_FL_Methyl-HT-SELEX 		0.708 0.698
SIX2
M05286_2.00 		Homo sapiens
NBRTATCRNN
NNYGATAYVN		 SELEX
Yin et al.(2017)
SIX2_eDBD_Methyl-HT-SELEX 		0.708 0.698
SIX2
M05288_2.00 		Homo sapiens
VBRTAWCRNN
NNYGWTAYVB		 SELEX
Yin et al.(2017)
SIX2_FL_Methyl-HT-SELEX 		0.708 0.698
ceh-34
M00672_2.00 		Caenorhabditis elegans
NNNRDAWNNN
NNNWTHYNNN		 PBM
Narasimhan et al.(2015)
pTH9708 		0.633 0.585
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSTRUP00000027003 Homeodomain 193 245
ENSTRUP00000027004 Homeodomain 185 237

Links

Other Homeodomain family TFs
Other Takifugu rubripes TFs

543 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
nAv.1.0.1.g02116 Acanthocheilonema viteae nAv.1.0.1.g02116 N
ACYPI005775 Acyrthosiphon pisum ACYPI005775 I
ASIM_0001958001 Anisakis simplex ASIM_0001958001 N
AALB006415 Anopheles albimanus AALB006415 I
AARA010616 Anopheles arabiensis AARA010616 I
AATE016215 Anopheles atroparvus AATE016215 I
ACUA004409 Anopheles culicifacies ACUA004409 I
ADAC003252 Anopheles darlingi ADAC003252 I
AFAF011136 Anopheles farauti AFAF011136 I
AGAP000281 Anopheles gambiae AGAP000281 I
AMEC012857 Anopheles melas AMEC012857 I
AMEM006878 Anopheles merus AMEM006878 I
ASIS016667 Anopheles sinensis ASIS016667 I
ASTEI07799 Anopheles stephensi ASTEI07799 I
GB43084 Apis mellifera GB43084 I
ACEP19638 Atta cephalotes ACEP19638 I
BGIBMGA006848 Bombyx mori BGIBMGA006848 I
fgenesh2_pg.scaffold_19000069 Branchiostoma floridae fgenesh2_pg.scaffold_19000069 N
fgenesh2_pg.scaffold_177000008 Branchiostoma floridae fgenesh2_pg.scaffold_177000008 N
Bm4188 Brugia malayi Bm4188 N
BTMF_0001006201 Brugia timori BTMF_0001006201 I
Cflo_00230--XP_624018.2_APIME Camponotus floridanus Cflo_00230--XP_624018.2_APIME N
CLEC001918 Cimex lectularius CLEC001918 I
ENSCING00000009516 Ciona intestinalis ENSCING00000009516 N
ENSCSAVG00000009270 Ciona savignyi ENSCSAVG00000009270 N
CGI_10017717 Crassostrea gigas CGI_10017717 I
KGM_14572 Danaus plexippus KGM_14572 I
tox4b Danio rerio ENSDARG00000100163 I
DAPPUDRAFT_19853 Daphnia pulex DAPPUDRAFT_19853 I
nDi.2.2.2.g11099 Dirofilaria immitis nDi.2.2.2.g11099 N
DME_0000632401 Dracunculus medinensis DME_0000632401 N
EEL_0000223401 Elaeophora elaphi EEL_0000223401 N
ENSGMOG00000013406 Gadus morhua ENSGMOG00000013406 N
ENSGMOG00000015161 Gadus morhua ENSGMOG00000015161 I
ENSGMOG00000008081 Gadus morhua ENSGMOG00000008081 N
tox4a Gasterosteus aculeatus ENSGACG00000014107 I
tox2 Gasterosteus aculeatus ENSGACG00000006914 N
GPUH_0000021901 Gongylonema pulchrum GPUH_0000021901 N
ENSGGOG00000025016 Gorilla gorilla ENSGGOG00000025016 I
HHAL000823-PA Halyomorpha halys HHAL000823-PA I
HMEL005034 Heliconius melpomene HMEL005034 I
HelroG145107 Helobdella robusta HelroG145107 N
ISCW018867 Ixodes scapularis ISCW018867 I
ISCW015985 Ixodes scapularis ISCW015985 N
nLs.2.1.2.g04689 Litomosoides sigmodontis nLs.2.1.2.g04689 N
LOAG_18151 Loa loa LOAG_18151 N
LotgiG109021 Lottia gigantea LotgiG109021 I
LCUP006200 Lucilia cuprina LCUP006200 N
ENSMMUG00000014077 Macaca mulatta ENSMMUG00000014077 N
MCINX005468 Melitaea cinxia MCINX005468 I
MDOA008605 Musca domestica MDOA008605 N
NV10488 Nasonia vitripennis NV10488 I
Ocbimv22012197m.g Octopus bimaculoides Ocbimv22012197m.g I
OFLC_0001222801 Onchocerca flexuosa OFLC_0001222801 N
nOo.2.0.1.g12207 Onchocerca ochengi nOo.2.0.1.g12207 N
WBGene00236865 Onchocerca volvulus WBGene00236865 N
ENSONIG00000000284 Oreochromis niloticus ENSONIG00000000284 N
ENSONIG00000016627 Oreochromis niloticus ENSONIG00000016627 N
tox2 Oryzias latipes ENSORLG00000004818 N
tox4b Oryzias latipes ENSORLG00000008779 N
ENSPFOG00000002336 Poecilia formosa ENSPFOG00000002336 N
ENSPFOG00000008402 Poecilia formosa ENSPFOG00000008402 N
RPRC000650 Rhodnius prolixus RPRC000650 I
nRc.2.0.1.g42996 Romanomermis culicivorax nRc.2.0.1.g42996 N
Sakowv30024549m.g Saccoglossus kowalevskii Sakowv30024549m.g N
SMU15029818 Schmidtea mediterranea SMU15029818 I
SPU_002060 Strongylocentrotus purpuratus SPU_002060 N
ENSSSCG00000023554 Sus scrofa ENSSSCG00000023554 N
ENSTGUG00000003811 Taeniopygia guttata ENSTGUG00000003811 N
tox4b Takifugu rubripes ENSTRUG00000002594 N
tox2 Takifugu rubripes ENSTRUG00000013848 N
tox4b Tetraodon nigroviridis ENSTNIG00000003691 N
tox2 Tetraodon nigroviridis ENSTNIG00000005683 N
TC012723 Tribolium castaneum TC012723 I
D917_02150 Trichinella nativa D917_02150 N
EFV61455 Trichinella spiralis EFV61455 N
TMUE_s0011001600 Trichuris muris TMUE_s0011001600 I
TMUE_s0009009400 Trichuris muris TMUE_s0009009400 N
D918_09264 Trichuris suis D918_09264 N
TTRE_0000401801 Trichuris trichiura TTRE_0000401801 I
TTRE_0000108401 Trichuris trichiura TTRE_0000108401 N
WUBG_03914 Wuchereria bancrofti WUBG_03914 N
tox4.S Xenopus laevis XB-GENE-993810 I
XP_002936155 Xenopus tropicalis XP_002936155 N
ENSXMAG00000016763 Xiphophorus maculatus ENSXMAG00000016763 N
ENSXMAG00000000362 Xiphophorus maculatus ENSXMAG00000000362 I