NR3C2 (Homo sapiens)
Nuclear receptor

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00105 (zf-C4) IPR001628 ENSG00000151623 T303235_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
NR3C2
M02395_2.00		 Homo sapiens
NNRGDACAN
NTGTHCYNN		 PBM
Weirauch et al.(2014)
pTH5924		 (Direct) (Direct)
NR3C2
M03382_2.00		 Homo sapiens
NRGDACAHDRTGTHCYN
NRGDACAYHDTGTHCYN		 SELEX
Jolma et al.(2013)
NR3C2_1		 (Direct) (Direct)
NR3C2
M05637_2.00		 Homo sapiens
NGNACRNNNYGTNCN
NGNACRNNNYGTNCN		 SELEX
Yin et al.(2017)
NR3C2_eDBD_HT-SELEX		 (Direct) (Direct)
NR3C2
M05638_2.00		 Homo sapiens
NGNACRNNVYGTNCN
NGNACRBNNYGTNCN		 SELEX
Yin et al.(2017)
NR3C2_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Nr3c1
M05886_2.00 		Mus musculus
DGDACDBYNTGTNCY
RGNACANRVHGTHCH		 SMiLE-seq
Isakova et al.(2017)
GR 		0.991 0.929
Nr3c1
M09318_2.00 		Mus musculus
RGNACABYNTGTNCY
RGNACANRVTGTNCY		 Misc
Kulakovskiy et al.(2013)
GCR_MOUSE.H11MO.0.A 		0.991 0.929
Nr3c1
M09614_2.00 		Mus musculus
NRGDACABNNTGTNC
GNACANNVTGTHCYN		 Misc
Heinz et al.(2010)
RAW264.7-GRE_Unpublished 		0.985 0.886
NR3C1
M03366_2.00 		Homo sapiens
NRGWACAYNRTGTWCYH
DRGWACAYNRTGTWCYN		 SELEX
Jolma et al.(2013)
NR3C1_1 		0.984 0.886
PGR
M03923_2.00 		Homo sapiens
DGNACANNNYGTNCY
RGNACRNNNTGTNCH		 SELEX
Nitta et al.(2015)
PGR_1 		0.990 0.900
NR3C1
M05587_2.00 		Homo sapiens
RGDACAYWDTGTHCY
RGDACAHWRTGTHCY		 SELEX
Yin et al.(2017)
NR3C1_eDBD_HT-SELEX 		0.984 0.886
PGR
M09266_2.00 		Homo sapiens
RGNACWBYBTGTNCYN
NRGNACAVRVWGTNCY		 Misc
Kulakovskiy et al.(2013)
PRGR_HUMAN.H11MO.0.A 		0.990 0.900
NR3C1
M07986_2.00 		Homo sapiens
DGNACABYBTGTNC
GNACAVRVTGTNCH		 ChIP-seq
Gerstein et al.(2012)
A549_GR_HudsonAlpha 		0.984 0.886
Pgr
M09326_2.00 		Mus musculus
RGNACWBYNTGTNCY
RGNACANRVWGTNCY		 Misc
Kulakovskiy et al.(2013)
PRGR_MOUSE.H11MO.0.A 		0.990 0.900
NR3C1
M07987_2.00 		Homo sapiens
NNNNRGNACAYBBTGTHCYNN
NNRGDACAVVRTGTNCYNNNN		 ChIP-seq
Gerstein et al.(2012)
ECC-1_GR_HudsonAlpha 		0.984 0.886
PGR
M09603_2.00 		Homo sapiens
RNACWNNNWGTNCHN
NDGNACWNNNWGTNY		 Misc
Heinz et al.(2010)
T47D-PR_GSE31130 		0.990 0.900
NR3C1
M09270_2.00 		Homo sapiens
DGNACABKNTGTNCY
RGNACANMVTGTNCH		 Misc
Kulakovskiy et al.(2013)
GCR_HUMAN.H11MO.0.A 		0.984 0.886
PGR
M11095_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PR_01 		0.990 0.900
PGR
M11096_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PR_02 		0.990 0.900
NR3C1
M09607_2.00 		Homo sapiens
NRGNACABNVTGTNCY
RGNACABNVTGTNCYN		 Misc
Heinz et al.(2010)
A549-GR_GSE32465 		0.984 0.886
PGR
M11097_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PR_Q6 		0.990 0.900
NR3C1
M11119_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GR_01 		0.984 0.886
NR3C1
M11120_2.00 		Homo sapiens
KKYACMRDVTGTYCTK
MAGRACABHYKGTRMM		 Transfac
Matys et al.(2006)
V$GRE_C 		0.984 0.886
NR3C1
M11121_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GR_Q4 		0.984 0.886
NR3C1
M11122_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GR_Q6_01 		0.984 0.886
NR3C1
M11123_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GR_Q6_02 		0.984 0.886
NR3C1
M11124_2.00 		Homo sapiens
NNWGVACANWDNNDNBHNN
NNDVNHNNHWNTGTBCWNN		 Transfac
Matys et al.(2006)
V$GR_Q6 		0.984 0.886
NR3C1
M11125_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NR3C1_04 		0.984 0.886
NR3C1
M05588_2.00 		Homo sapiens
RGDACANDRYGTHCY
RGDACRYHNTGTHCY		 SELEX
Yin et al.(2017)
NR3C1_eDBD_Methyl-HT-SELEX 		0.984 0.886
Ar
M00821_2.00 		Mus musculus
NRRGAACAYN
NRTGTTCYYN		 PBM
Weirauch et al.(2013)
pTH1739 		0.971 0.786
AR
M03389_2.00 		Homo sapiens
DRGWACRHVDYGTWCCY
RGGWACRHBDYGTWCYH		 SELEX
Jolma et al.(2013)
AR_1 		0.974 0.771
AR
M03390_2.00 		Homo sapiens
DRGWACAYNRTGTWCYY
RRGWACAYNRTGTWCYH		 SELEX
Jolma et al.(2013)
AR_2 		0.971 0.786
Ar
M03436_2.00 		Mus musculus
NRGHACAYNVYGTWCYN
NRGWACRBNRTGTDCYN		 SELEX
Jolma et al.(2013)
Ar_1 		0.971 0.786
AR
M09288_2.00 		Homo sapiens
DRYAAAYADNNNRGNACA
TGTNCYNNNHTRTTTRYH		 Misc
Kulakovskiy et al.(2013)
ANDR_HUMAN.H11MO.0.A 		0.971 0.786
Ar
M09331_2.00 		Mus musculus
NRGNACABRVTGTNCY
RGNACABYVTGTNCYN		 Misc
Kulakovskiy et al.(2013)
ANDR_MOUSE.H11MO.0.A 		0.971 0.786
AR
M09610_2.00 		Homo sapiens
NRGNACABNVTGTNCY
RGNACABNVTGTNCYN		 Misc
Heinz et al.(2010)
LNCAP-AR_GSE27824 		0.971 0.786
AR
M09609_2.00 		Homo sapiens
SHDRGVACAS
STGTBCYHDS		 Misc
Heinz et al.(2010)
LNCaP-AR_GSE27824 		0.974 0.771
AR
M11157_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AR_01 		0.974 0.771
AR
M11158_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AR_02 		0.974 0.771
AR
M11159_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AR_03 		0.974 0.771
AR
M11160_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AR_04 		0.974 0.771
AR
M11161_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AR_11 		0.971 0.786
AR
M11162_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AR_13 		0.974 0.771
AR
M11163_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AR_14_H 		0.974 0.771
AR
M11164_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AR_Q2 		0.971 0.786
AR
M11165_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AR_Q6_01 		0.971 0.786
AR
M11166_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AR_Q6 		0.974 0.771
For this family, TFs with SR scores > 0.745 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M02395_2.00 Nuclear receptor 1 70

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000341390 Nuclear receptor 601 670
ENSP00000343907 Nuclear receptor 601 670
ENSP00000350815 Nuclear receptor 601 670
ENSP00000421481 Nuclear receptor 601 674
ENSP00000423510 Nuclear receptor 601 670
ENSP00000486719 Nuclear receptor 601 674

Links

Other Nuclear receptor family TFs
Other Homo sapiens TFs

276 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSAMEG00000011947 Ailuropoda melanoleuca ENSAMEG00000011947 I
ENSAMEG00000018046 Ailuropoda melanoleuca ENSAMEG00000018046 I
Alligator_sinensis_CCG001816.1 Alligator sinensis Alligator_sinensis_CCG001816.1 I
Alligator_sinensis_CCG003243.1 Alligator sinensis Alligator_sinensis_CCG003243.1 I
Alligator_sinensis_CCG007409.1 Alligator sinensis Alligator_sinensis_CCG007409.1 I
Alligator_sinensis_CCG015693.1 Alligator sinensis Alligator_sinensis_CCG015693.1 I
ENSAPLG00000012813 Anas platyrhynchos ENSAPLG00000012813 I
CREB3L2 Anolis carolinensis ENSACAG00000011643 I
Afo_R001188 Aptenodytes forsteri Afo_R001188 I
Afo_R012529 Aptenodytes forsteri Afo_R012529 I
ENSAMXG00000001763 Astyanax mexicanus ENSAMXG00000001763 I
ENSAMXG00000011038 Astyanax mexicanus ENSAMXG00000011038 I
ENSAMXG00000012038 Astyanax mexicanus ENSAMXG00000012038 I
ENSBTAP00000020987-D1 Bos grunniens ENSBTAP00000020987-D1 I
ENSP00000271889-D1 Bos grunniens ENSP00000271889-D1 I
CREB3L4 Bos taurus ENSBTAG00000014692 I
CREB3L2 Bos taurus ENSBTAG00000015802 I
Brh_R001055 Buceros rhinoceros Brh_R001055 I
Brh_R004937 Buceros rhinoceros Brh_R004937 I
CREB3L4 Callithrix jacchus ENSCJAG00000009978 I
CREB3L2 Callithrix jacchus ENSCJAG00000012834 I
Aan_R004874 Calypte anna Aan_R004874 I
CREB3L2 Canis familiaris ENSCAFG00000013481 I
CREB3L4 Canis familiaris ENSCAFG00000017395 I
CREB3L2 Cavia porcellus ENSCPOG00000008872 I
ENSCPOG00000012896 Cavia porcellus ENSCPOG00000012896 I
Cmyd_10002091 Chelonia mydas Cmyd_10002091 I
Cmyd_10005057 Chelonia mydas Cmyd_10005057 I
Cmyd_10012869 Chelonia mydas Cmyd_10012869 I
ENSCSAG00000001896 Chlorocebus sabaeus ENSCSAG00000001896 I
ENSCSAG00000008752 Chlorocebus sabaeus ENSCSAG00000008752 I
CREB3L4 Choloepus hoffmanni ENSCHOG00000002522 I
creb3l3a Danio rerio ENSDARG00000056226 I
creb3l2 Danio rerio ENSDARG00000063563 I
creb3l3b Danio rerio ENSDARG00000090903 I
CREB3L2 Dasypus novemcinctus ENSDNOG00000004102 I
CREB3L4 Dasypus novemcinctus ENSDNOG00000042769 I
Creb3l2 Dipodomys ordii ENSDORG00000002788 I
Creb3l4 Dipodomys ordii ENSDORG00000011769 I
CREB3L4 Echinops telfairi ENSETEG00000008252 I
CREB3L2 Equus caballus ENSECAG00000007609 I
CREB3L4 Equus caballus ENSECAG00000017552 I
CREB3L2 Felis catus ENSFCAG00000000648 I
CREB3L4 Felis catus ENSFCAG00000012586 I
ENSFALG00000000511 Ficedula albicollis ENSFALG00000000511 I
ENSFALG00000000900 Ficedula albicollis ENSFALG00000000900 I
ENSGMOG00000010438 Gadus morhua ENSGMOG00000010438 I
ENSGALG00000002523 Gallus gallus ENSGALG00000002523 I
CREB3L2 Gallus gallus ENSGALG00000012877 I
creb3l2 Gasterosteus aculeatus ENSGACG00000020083 I
Gfo_R015139 Geospiza fortis Gfo_R015139 I
CREB3L2 Gorilla gorilla ENSGGOG00000004216 I
CREB3L4 Gorilla gorilla ENSGGOG00000005601 I
CREB3L4 Homo sapiens ENSG00000143578 D
CREB3L2 Homo sapiens ENSG00000182158 I
ENSSTOG00000009818 Ictidomys tridecemlineatus ENSSTOG00000009818 I
ENSSTOG00000014516 Ictidomys tridecemlineatus ENSSTOG00000014516 I
ISCW001814 Ixodes scapularis ISCW001814 I
ENSLACG00000008535 Latimeria chalumnae ENSLACG00000008535 I
ENSLACG00000009185 Latimeria chalumnae ENSLACG00000009185 I
ENSLOCG00000006221 Lepisosteus oculatus ENSLOCG00000006221 I
ENSLOCG00000008658 Lepisosteus oculatus ENSLOCG00000008658 I
CREB3L2 Loxodonta africana ENSLAFG00000008469 I
ENSP00000271889 Macaca fascicularis ENSP00000271889 I
ENSP00000329140 Macaca fascicularis ENSP00000329140 I
CREB3L4 Macaca mulatta ENSMMUG00000005008 I
ENSMEUG00000013573 Macropus eugenii ENSMEUG00000013573 I
CREB3L2 Meleagris gallopavo ENSMGAG00000013250 I
CREB3L2 Microcebus murinus ENSMICG00000003960 I
CREB3L4 Microcebus murinus ENSMICG00000010316 I
CREB3L3 Monodelphis domestica ENSMODG00000000817 I
CREB3L2 Monodelphis domestica ENSMODG00000013876 D
CREB3L4 Monodelphis domestica ENSMODG00000017299 I
ENSMPUG00000003955 Mustela putorius furo ENSMPUG00000003955 I
ENSMPUG00000007975 Mustela putorius furo ENSMPUG00000007975 I
Creb3l2 Mus musculus ENSMUSG00000038648 D
Myotis_brandtii_CREB3L2_10008636 Myotis brandtii Myotis_brandtii_CREB3L2_10008636 I
Myotis_brandtii_CREB3L3_10016301 Myotis brandtii Myotis_brandtii_CREB3L3_10016301 I
Myotis_brandtii_CREB3L4_10031903 Myotis brandtii Myotis_brandtii_CREB3L4_10031903 I
CREB3L3 Myotis lucifugus ENSMLUG00000008703 I
CREB3L4 Myotis lucifugus ENSMLUG00000013291 I
CREB3L2 Myotis lucifugus ENSMLUG00000030474 I
NEMVEDRAFT_v1g243817 Nematostella vectensis NEMVEDRAFT_v1g243817 I
NEMVEDRAFT_v1g28519 Nematostella vectensis NEMVEDRAFT_v1g28519 I
ENSNLEG00000010798 Nomascus leucogenys ENSNLEG00000010798 I
ENSNLEG00000026880 Nomascus leucogenys ENSNLEG00000026880 I
CREB3L4 Ochotona princeps ENSOPRG00000003982 I
Ogr06733 Ophisaurus gracilis Ogr06733 I
ENSONIG00000017874 Oreochromis niloticus ENSONIG00000017874 I
CREB3L2 Oryctolagus cuniculus ENSOCUG00000007313 I
CREB3L4 Oryctolagus cuniculus ENSOCUG00000011784 I
creb3l3a Oryzias latipes ENSORLG00000004610 I
CREB3L2 Otolemur garnettii ENSOGAG00000010846 I
ENSOARG00000001743 Ovis aries ENSOARG00000001743 I
ENSOARG00000009957 Ovis aries ENSOARG00000009957 I
CREB3L4 Pan troglodytes ENSPTRG00000001368 I
CREB3L2 Pan troglodytes ENSPTRG00000019739 I
ENSPANG00000006363 Papio anubis ENSPANG00000006363 I
ENSPANG00000010323 Papio anubis ENSPANG00000010323 I
ENSPSIG00000006461 Pelodiscus sinensis ENSPSIG00000006461 I
ENSPFOG00000002309 Poecilia formosa ENSPFOG00000002309 I
ENSPFOG00000012285 Poecilia formosa ENSPFOG00000012285 I
Pvit_02332 Pogona vitticeps Pvit_02332 I
Pvit_09828 Pogona vitticeps Pvit_09828 I
Pvit_14149 Pogona vitticeps Pvit_14149 I
ENSPPYG00000000792 Pongo abelii ENSPPYG00000000792 I
ENSPPYG00000018036 Pongo abelii ENSPPYG00000018036 I
CREB3L4 Procavia capensis ENSPCAG00000003143 I
CREB3L2 Procavia capensis ENSPCAG00000014875 I
CREB3L4 Pteropus vampyrus ENSPVAG00000011092 I
Creb3l2 Rattus norvegicus ENSRNOG00000012826 I
ENSSHAG00000011584 Sarcophilus harrisii ENSSHAG00000011584 I
ENSSHAG00000011761 Sarcophilus harrisii ENSSHAG00000011761 I
ENSSARG00000011575 Sorex araneus ENSSARG00000011575 I
CREB3L4 Sus scrofa ENSSSCG00000006560 I
CREB3L2 Sus scrofa ENSSSCG00000016520 I
CREB3L2 Taeniopygia guttata ENSTGUG00000011582 I
CREB3L4 Takifugu rubripes ENSTRUG00000011094 I
creb3l3l Tetraodon nigroviridis ENSTNIG00000016667 I
CREB3L2 Tupaia belangeri ENSTBEG00000004887 I
CREB3L2 Tursiops truncatus ENSTTRG00000004842 I
Tal_R001519 Tyto alba Tal_R001519 I
creb3l2.L Xenopus laevis XB-GENE-996214 I
creb3l4 Xenopus tropicalis XB-GENE-5761389 I
ENSXMAG00000001292 Xiphophorus maculatus ENSXMAG00000001292 I
ENSXMAG00000004377 Xiphophorus maculatus ENSXMAG00000004377 I