CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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Thap1
(
Rattus norvegicus
)
THAP finger
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF05485 (THAP)
IPR006612
ENSRNOG00000056956
T348683_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Predicted to enable several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; protein homodimerization activity; and zinc ion binding activity. Predicted to be involved in several processes, including endothelial cell proliferation; negative regulation of transcription by RNA polymerase II; and transcription, DNA-templated. Predicted to be located in fibrillar center and nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in torsion dystonia 6. Orthologous to human THAP1 (THAP domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
No direct experiments
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
THAP1
M08176_2.00
Homo sapiens
DNHKGGMRR
YYKCCMDNH
ChIP-seq
Mathelier et al.(2014)
MA0597.1
0.987
0.987
THAP1
M08020_2.00
Homo sapiens
SGCCATBTTKRNWVHGGGCRR
YYGCCCDBWNYMAAVATGGCS
ChIP-seq
Gerstein et al.(2012)
K562_THAP1_HudsonAlpha
0.987
0.987
THAP1
M09439_2.00
Homo sapiens
GCCCDVVNBVRVSVKGGCBSCB
VGSVGCCMBSBYBVNBBHGGGC
Misc
Kulakovskiy et al.(2013)
THAP1_HUMAN.H11MO.0.C
0.987
0.987
THAP1
M11412_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$THAP1_01
0.987
0.987
THAP1
M11413_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$THAP1_02
0.987
0.987
THAP1
M11414_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$THAP1_04
0.987
0.987
For this family, TFs with SR scores >
0.700
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSRNOP00000071777
THAP finger
4
83
SCSAYGCKNRYDKDKPVSFHKFPLTRPSLCKQWEAAVRRKNFKPTKYSSICSEHFTPDCFKRECNNKLLKENAVPTIFLY
Links
Other
THAP finger
family TFs
Other
Rattus norvegicus
TFs
58 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy