Thap1 (Rattus norvegicus)
THAP finger

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF05485 (THAP) IPR006612 ENSRNOG00000056956 T348683_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; protein homodimerization activity; and zinc ion binding activity. Predicted to be involved in several processes, including endothelial cell proliferation; negative regulation of transcription by RNA polymerase II; and transcription, DNA-templated. Predicted to be located in fibrillar center and nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in torsion dystonia 6. Orthologous to human THAP1 (THAP domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
THAP1
M08176_2.00 		Homo sapiens
DNHKGGMRR
YYKCCMDNH		 ChIP-seq
Mathelier et al.(2014)
MA0597.1 		0.987 0.987
THAP1
M08020_2.00 		Homo sapiens
SGCCATBTTKRNWVHGGGCRR
YYGCCCDBWNYMAAVATGGCS		 ChIP-seq
Gerstein et al.(2012)
K562_THAP1_HudsonAlpha 		0.987 0.987
THAP1
M09439_2.00 		Homo sapiens
GCCCDVVNBVRVSVKGGCBSCB
VGSVGCCMBSBYBVNBBHGGGC		 Misc
Kulakovskiy et al.(2013)
THAP1_HUMAN.H11MO.0.C 		0.987 0.987
THAP1
M11412_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$THAP1_01 		0.987 0.987
THAP1
M11413_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$THAP1_02 		0.987 0.987
THAP1
M11414_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$THAP1_04 		0.987 0.987
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSRNOP00000071777 THAP finger 4 83

Links

Other THAP finger family TFs
Other Rattus norvegicus TFs

58 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSCPOG00000021608 Cavia porcellus ENSCPOG00000021608 I 1.000
ENSNLEG00000012946 Nomascus leucogenys ENSNLEG00000012946 I 0.987
THAP1 Oryctolagus cuniculus ENSOCUG00000001391 I 0.987
THAP1 Vicugna pacos ENSVPAG00000001157 I 0.987
THAP1 Echinops telfairi ENSETEG00000018764 I 0.987
THAP1 Felis catus ENSFCAG00000027837 I 0.987
THAP1 Gorilla gorilla ENSGGOG00000022708 I 0.987
ENSPANG00000007346 Papio anubis ENSPANG00000007346 I 0.987
THAP1 Loxodonta africana ENSLAFG00000003647 I 0.987
THAP1 Homo sapiens ENSG00000131931 D 0.987
THAP1 Dasypus novemcinctus ENSDNOG00000047233 I 0.987
ENSMMUG00000000162 Macaca mulatta ENSMMUG00000000162 I 0.987
THAP1 Canis familiaris ENSCAFG00000005418 I 0.987
Thap1 Mus musculus ENSMUSG00000037214 I 0.987
ENSP00000254250 Macaca fascicularis ENSP00000254250 I 0.987
ENSAMEG00000004992 Ailuropoda melanoleuca ENSAMEG00000004992 I 0.987
THAP1 Pan troglodytes ENSPTRG00000020211 I 0.987
ENSCSAG00000014961 Chlorocebus sabaeus ENSCSAG00000014961 I 0.987
THAP1 Callithrix jacchus ENSCJAG00000003466 I 0.987
ENSCHOG00000005563 Choloepus hoffmanni ENSCHOG00000005563 I 0.987
ENSCHOG00000005457 Choloepus hoffmanni ENSCHOG00000005457 I 0.982
THAP1 Otolemur garnettii ENSOGAG00000002708 I 0.974
THAP1 Erinaceus europaeus ENSEEUG00000003332 I 0.974
ENSBTAP00000010035-D1 Bos grunniens ENSBTAP00000010035-D1 I 0.974
THAP1 Bos taurus ENSBTAG00000007629 I 0.974
THAP1 Pteropus vampyrus ENSPVAG00000013496 I 0.974
THAP1 Tursiops truncatus ENSTTRG00000008823 I 0.974
ENSSTOG00000023122 Ictidomys tridecemlineatus ENSSTOG00000023122 I 0.974
ENSSSCG00000027223 Sus scrofa ENSSSCG00000027223 I 0.974
ENSOARG00000003516 Ovis aries ENSOARG00000003516 I 0.947
THAP1 Monodelphis domestica ENSMODG00000010093 I 0.947
ENSDORG00000014207 Dipodomys ordii ENSDORG00000014207 I 0.946
ENSTSYG00000006585 Tarsius syrichta ENSTSYG00000006585 I 0.934
Pvit_16121 Pogona vitticeps Pvit_16121 I 0.908
THAP1 Gallus gallus ENSGALG00000015385 I 0.908
ENSFALG00000005181 Ficedula albicollis ENSFALG00000005181 I 0.908
THAP1 Anolis carolinensis ENSACAG00000005705 I 0.908
Myotis_brandtii_thap1_10030544 Myotis brandtii Myotis_brandtii_thap1_10030544 I 0.882
THAP1 Myotis lucifugus ENSMLUG00000003837 I 0.882
thap1.L Xenopus laevis XB-GENE-1008764 I 0.868
thap1 Xenopus tropicalis XB-GENE-1008758 I 0.868
AAH77429 Xenopus laevis AAH77429 I 0.842
ENSLACG00000003453 Latimeria chalumnae ENSLACG00000003453 I 0.842
Aan_R002310 Calypte anna Aan_R002310 I 0.831
ENSLACG00000000288 Latimeria chalumnae ENSLACG00000000288 I 0.829
Tal_R008759 Tyto alba Tal_R008759 I 0.818
Afo_R005722 Aptenodytes forsteri Afo_R005722 I 0.818
ENSAMXG00000007136 Astyanax mexicanus ENSAMXG00000007136 I 0.776
thap1 Oryzias latipes ENSORLG00000018779 I 0.763
ENSLOCG00000003237 Lepisosteus oculatus ENSLOCG00000003237 I 0.763
thap1 Gasterosteus aculeatus ENSGACG00000018371 I 0.750
ENSPFOG00000004261 Poecilia formosa ENSPFOG00000004261 I 0.750
ENSXMAG00000003907 Xiphophorus maculatus ENSXMAG00000003907 I 0.737
ENSONIG00000012619 Oreochromis niloticus ENSONIG00000012619 I 0.737
THAP1 Ornithorhynchus anatinus ENSOANG00000000699 I 0.730
THAP1 Equus caballus ENSECAG00000000020 I 0.724
Brh_R003908 Buceros rhinoceros Brh_R003908 I 0.724
thap1 Danio rerio ENSDARG00000059020 N 0.711