| NCBI Gene Info:Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in anatomical structure development; positive regulation of transcription by RNA polymerase II; and regulation of cell population proliferation. Predicted to be active in nucleus. Is expressed in head neurons and intestine. Human ortholog(s) of this gene implicated in Char syndrome; branchiooculofacial syndrome; and patent ductus arteriosus. Orthologous to several human genes including TFAP2A (transcription factor AP-2 alpha); TFAP2B (transcription factor AP-2 beta); and TFAP2D (transcription factor AP-2 delta). [provided by Alliance of Genome Resources, Apr 2022] |