aptf-1 (Caenorhabditis elegans)
AP-2

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF03299 (TF_AP-2) IPR013854 WBGene00019424 T011139_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II and sleep. Predicted to be active in nucleus. Is expressed in head neurons and pharyngeal neurons. Human ortholog(s) of this gene implicated in Char syndrome; branchiooculofacial syndrome; and patent ductus arteriosus. Orthologous to several human genes including TFAP2A (transcription factor AP-2 alpha); TFAP2D (transcription factor AP-2 delta); and TFAP2E (transcription factor AP-2 epsilon). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
K06A1.1 AP-2 152 355

Links

Other AP-2 family TFs
Other Caenorhabditis elegans TFs

26 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CBN19319 Caenorhabditis brenneri CBN19319 N 0.980
ANCCEY_07283 Ancylostoma ceylanicum ANCCEY_07283 I 0.977
CRE26538 Caenorhabditis remanei CRE26538 N 0.974
CJA15225 Caenorhabditis japonica CJA15225 N 0.939
CBG02662 Caenorhabditis briggsae CBG02662 N 0.832
NECAME_08596 Necator americanus NECAME_08596 N 0.827
OESDEN_04908 Oesophagostomum dentatum OESDEN_04908 N 0.827
ANCCAN_03137 Ancylostoma caninum ANCCAN_03137 N 0.816
genemark-nMf.1.1.scaf12791-processed-gene-0.1 Meloidogyne floridensis genemark-nMf.1.1.scaf12791-processed-gene-0.1 I 0.815
MhA1_Contig1235.frz3.gene9 Meloidogyne hapla MhA1_Contig1235.frz3.gene9 I 0.815
ASIM_0000382801 Anisakis simplex ASIM_0000382801 N 0.811
HPLM_0001199101 Haemonchus placei HPLM_0001199101 N 0.806
HCOI00892700 Haemonchus contortus HCOI00892700 N 0.806
DICVIV_00217 Dictyocaulus viviparus DICVIV_00217 N 0.801
tfap2b Danio rerio ENSDARG00000012667 I 0.795
ENSGACG00000002672 Gasterosteus aculeatus ENSGACG00000002672 I 0.795
ENSGMOG00000009513 Gadus morhua ENSGMOG00000009513 I 0.795
snap_masked-nMf.1.1.scaf31395-processed-gene-0.2 Meloidogyne floridensis snap_masked-nMf.1.1.scaf31395-processed-gene-0.2 I 0.786
ANCDUO_26474 Ancylostoma duodenale ANCDUO_26474 N 0.773
ECPE_0000534101 Echinostoma caproni ECPE_0000534101 I 0.739
ENSMEUG00000007703 Macropus eugenii ENSMEUG00000007703 I 0.738
TFAP2D Microcebus murinus ENSMICG00000005507 I 0.730
MCINX002204 Melitaea cinxia MCINX002204 I 0.725
Hba_16110 Heterorhabditis bacteriophora Hba_16110 N 0.709
ACEP15405 Atta cephalotes ACEP15405 I 0.708
nAv.1.0.1.g06665 Acanthocheilonema viteae nAv.1.0.1.g06665 I 0.705