TFEC (Homo sapiens)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSG00000105967 T034258_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
TFEC
M02778_2.00		 Homo sapiens
RNCACRTGAB
VTCAYGTGNY		 SELEX
Jolma et al.(2013)
TFEC_1		 (Direct) (Direct)
TFEC
M04078_2.00		 Homo sapiens
NVCACGTGACN
NGTCACGTGBN		 SELEX
Yin et al.(2017)
TFEC_eDBD_HT-SELEX		 (Direct) (Direct)
TFEC
M04079_2.00		 Homo sapiens
VNCATGTGAYN
NRTCACATGNB		 SELEX
Yin et al.(2017)
TFEC_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Tfec
M00755_2.00 		Mus musculus
NNCACGTGNN
NNCACGTGNN		 PBM
Weirauch et al.(2013)
pTH2885 		0.914 0.981
Tfec
M01736_2.00 		Mus musculus
NCNCRTGVYN
NRBCAYGNGN		 PBM
Weirauch et al.(2014)
pTH5065 		0.914 0.981
Mitf
M01741_2.00 		Mus musculus
NCDCGTGAYN
NRTCACGHGN		 PBM
Weirauch et al.(2014)
pTH5465 		0.870 0.907
MITF
M08058_2.00 		Homo sapiens
NNNDRTCACGTGAYHNNN
NNNDRTCACGTGAYHNNN		 ChIP-seq
Mathelier et al.(2014)
MA0620.2 		0.870 0.907
MITF
M08740_2.00 		Homo sapiens
YCAYGTGACH
DGTCACRTGR		 Misc
Kulakovskiy et al.(2013)
MITF_HUMAN.H11MO.0.A 		0.870 0.907
Mitf
M08765_2.00 		Mus musculus
BCHYGTGACY
RGTCACRDGV		 Misc
Kulakovskiy et al.(2013)
MITF_MOUSE.H11MO.0.A 		0.870 0.907
Mitf
M09475_2.00 		Mus musculus
GTCACRWGVB
VBCWYGTGAC		 Misc
Heinz et al.(2010)
MastCells-MITF_GSE48085 		0.870 0.907
MITF
M09880_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MITF_Q4 		0.870 0.907
MITF
M09881_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MITF_Q6 		0.870 0.907
Tfe3
M01715_2.00 		Mus musculus
NCDCRTGAYN
NRTCAYGHGN		 PBM
Weirauch et al.(2014)
pTH5057 		0.870 0.889
Tfe3
M05833_2.00 		Mus musculus
CACGTGAY
RTCACGTG		 SMiLE-seq
Isakova et al.(2017)
TFE3 		0.870 0.889
Tfe3
M08743_2.00 		Mus musculus
TCACGTGACH
DGTCACGTGA		 Misc
Kulakovskiy et al.(2013)
TFE3_MOUSE.H11MO.0.A 		0.870 0.889
Tfe3
M09884_2.00 		Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TFEA_01 		0.870 0.889
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000265440 bHLH 140 193
ENSP00000318676 bHLH 111 164
ENSP00000377125 bHLH 111 164
ENSP00000387650 bHLH 73 126
ENSP00000417432 bHLH 230 283

Links

Other bHLH family TFs
Other Homo sapiens TFs

149 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
TFEC Anolis carolinensis ENSACAG00000006672 I 0.914
ENSAMEG00000018238 Ailuropoda melanoleuca ENSAMEG00000018238 I 0.914
ENSAMXG00000021026 Astyanax mexicanus ENSAMXG00000021026 I 0.914
ENSAPLG00000012143 Anas platyrhynchos ENSAPLG00000012143 I 0.914
TFEC Bos taurus ENSBTAG00000014228 I 0.914
TFEC Canis familiaris ENSCAFG00000003397 I 0.914
TFEC Choloepus hoffmanni ENSCHOG00000001149 I 0.914
TFEC Callithrix jacchus ENSCJAG00000005199 I 0.914
TFEC Cavia porcellus ENSCPOG00000012369 I 0.914
ENSCSAG00000010942 Chlorocebus sabaeus ENSCSAG00000010942 I 0.914
tfec Danio rerio ENSDARG00000098745 I 0.914
ENSDNOG00000045240 Dasypus novemcinctus ENSDNOG00000045240 I 0.914
Tfec Dipodomys ordii ENSDORG00000004403 I 0.914
TFEC Equus caballus ENSECAG00000013937 I 0.914
ENSFALG00000010129 Ficedula albicollis ENSFALG00000010129 I 0.914
TFEC Felis catus ENSFCAG00000027627 I 0.914
tfec Gasterosteus aculeatus ENSGACG00000018910 I 0.914
ENSGALG00000009411 Gallus gallus ENSGALG00000009411 I 0.914
TFEC Gorilla gorilla ENSGGOG00000009901 I 0.914
ENSGMOG00000009209 Gadus morhua ENSGMOG00000009209 I 0.914
ENSLOCG00000015941 Lepisosteus oculatus ENSLOCG00000015941 I 0.914
ENSMEUG00000009307 Macropus eugenii ENSMEUG00000009307 I 0.914
TFEC Meleagris gallopavo ENSMGAG00000008979 I 0.914
TFEC Microcebus murinus ENSMICG00000006995 I 0.914
ENSMMUG00000016347 Macaca mulatta ENSMMUG00000016347 I 0.914
ENSMODG00000015845 Monodelphis domestica ENSMODG00000015845 I 0.914
ENSMPUG00000007248 Mustela putorius furo ENSMPUG00000007248 I 0.914
Tfec Mus musculus ENSMUSG00000029553 D 0.914
ENSNLEG00000011480 Nomascus leucogenys ENSNLEG00000011480 I 0.914
TFEC Ornithorhynchus anatinus ENSOANG00000014094 I 0.914
ENSOARG00000001668 Ovis aries ENSOARG00000001668 I 0.914
TFEC Oryctolagus cuniculus ENSOCUG00000006292 I 0.914
TFEC Otolemur garnettii ENSOGAG00000010066 I 0.914
ENSONIG00000016803 Oreochromis niloticus ENSONIG00000016803 I 0.914
tfec Oryzias latipes ENSORLG00000010461 I 0.914
ENSPANG00000022367 Papio anubis ENSPANG00000022367 I 0.914
ENSPFOG00000014522 Poecilia formosa ENSPFOG00000014522 I 0.914
ENSPPYG00000017928 Pongo abelii ENSPPYG00000017928 I 0.914
ENSPSIG00000015144 Pelodiscus sinensis ENSPSIG00000015144 I 0.914
TFEC Pan troglodytes ENSPTRG00000019610 I 0.914
Tfec Rattus norvegicus ENSRNOG00000061595 I 0.914
ENSSHAG00000012198 Sarcophilus harrisii ENSSHAG00000012198 I 0.914
ENSSSCG00000016637 Sus scrofa ENSSSCG00000016637 I 0.914
ENSSTOG00000001224 Ictidomys tridecemlineatus ENSSTOG00000001224 I 0.914
TFEC Taeniopygia guttata ENSTGUG00000005289 I 0.914
tfec Tetraodon nigroviridis ENSTNIG00000018518 I 0.914
ENSTSYG00000008234 Tarsius syrichta ENSTSYG00000008234 I 0.914
TFEC Tursiops truncatus ENSTTRG00000005875 I 0.914
TFEC Vicugna pacos ENSVPAG00000005459 I 0.914
ENSXMAG00000009146 Xiphophorus maculatus ENSXMAG00000009146 I 0.914
Aan_R002066 Calypte anna Aan_R002066 I 0.914
Afo_R003542 Aptenodytes forsteri Afo_R003542 I 0.914
Brh_R012392 Buceros rhinoceros Brh_R012392 I 0.914
ENSP00000265440-D1 Bos grunniens ENSP00000265440-D1 I 0.914
ENSP00000265440 Macaca fascicularis ENSP00000265440 I 0.914
Gfo_R005766 Geospiza fortis Gfo_R005766 I 0.914
Pvit_16445 Pogona vitticeps Pvit_16445 I 0.914
Tal_R000725 Tyto alba Tal_R000725 I 0.914
ENSLACG00000008018 Latimeria chalumnae ENSLACG00000008018 I 0.884
TFEC Loxodonta africana ENSLAFG00000017267 I 0.884
TFEC Myotis lucifugus ENSMLUG00000008952 I 0.871
Myotis_brandtii_TFEC_10018991 Myotis brandtii Myotis_brandtii_TFEC_10018991 I 0.871
MITF Anolis carolinensis ENSACAG00000013586 I 0.870
TFE3 Anolis carolinensis ENSACAG00000022140 I 0.870
ENSAMEG00000017117 Ailuropoda melanoleuca ENSAMEG00000017117 I 0.870
ENSAPLG00000011965 Anas platyrhynchos ENSAPLG00000011965 I 0.870
MITF Bos taurus ENSBTAG00000006679 I 0.870
MITF Canis familiaris ENSCAFG00000006496 I 0.870
MITF Callithrix jacchus ENSCJAG00000013260 I 0.870
TFE3 Cavia porcellus ENSCPOG00000012410 I 0.870
MITF Cavia porcellus ENSCPOG00000014963 I 0.870
ENSCSAG00000011595 Chlorocebus sabaeus ENSCSAG00000011595 I 0.870
mitfa Danio rerio ENSDARG00000003732 I 0.870
mitfb Danio rerio ENSDARG00000037833 I 0.870
MITF Dasypus novemcinctus ENSDNOG00000037006 I 0.870
Mitf Dipodomys ordii ENSDORG00000003336 I 0.870
ENSDORG00000013258 Dipodomys ordii ENSDORG00000013258 I 0.870
MITF Equus caballus ENSECAG00000005360 I 0.870
MITF Erinaceus europaeus ENSEEUG00000005163 I 0.870
ENSFALG00000013383 Ficedula albicollis ENSFALG00000013383 I 0.870
MITF Felis catus ENSFCAG00000024419 I 0.870
MITF Homo sapiens ENSG00000187098 D 0.870
mitfb Gasterosteus aculeatus ENSGACG00000003425 I 0.870
tfe3b Gasterosteus aculeatus ENSGACG00000010355 I 0.870
mitfa Gasterosteus aculeatus ENSGACG00000011875 I 0.870
ENSGALG00000007679 Gallus gallus ENSGALG00000007679 I 0.870
MITF Gorilla gorilla ENSGGOG00000024338 I 0.870
ENSGMOG00000007421 Gadus morhua ENSGMOG00000007421 I 0.870
ENSGMOG00000010175 Gadus morhua ENSGMOG00000010175 I 0.870
ENSLACG00000011547 Latimeria chalumnae ENSLACG00000011547 I 0.870
MITF Loxodonta africana ENSLAFG00000023153 I 0.870
ENSLOCG00000010058 Lepisosteus oculatus ENSLOCG00000010058 I 0.870
MITF Meleagris gallopavo ENSMGAG00000009507 I 0.870
ENSMICG00000002894 Microcebus murinus ENSMICG00000002894 I 0.870
MITF Myotis lucifugus ENSMLUG00000002587 I 0.870
MITF Macaca mulatta ENSMMUG00000002100 I 0.870
MITF Monodelphis domestica ENSMODG00000003754 I 0.870
ENSMPUG00000016972 Mustela putorius furo ENSMPUG00000016972 I 0.870
Tfe3 Mus musculus ENSMUSG00000000134 D 0.870
Mitf Mus musculus ENSMUSG00000035158 D 0.870
ENSNLEG00000002357 Nomascus leucogenys ENSNLEG00000002357 I 0.870
ENSOANG00000012406 Ornithorhynchus anatinus ENSOANG00000012406 I 0.870
TFE3 Ornithorhynchus anatinus ENSOANG00000013574 I 0.870
ENSOARG00000009833 Ovis aries ENSOARG00000009833 I 0.870
MITF Oryctolagus cuniculus ENSOCUG00000002190 I 0.870
MITF Otolemur garnettii ENSOGAG00000000043 I 0.870
ENSONIG00000016952 Oreochromis niloticus ENSONIG00000016952 I 0.870
ENSONIG00000020270 Oreochromis niloticus ENSONIG00000020270 I 0.870
mitfa Oryzias latipes ENSORLG00000003123 I 0.870
mitfb Oryzias latipes ENSORLG00000013461 I 0.870
ENSPANG00000011565 Papio anubis ENSPANG00000011565 I 0.870
ENSPFOG00000006677 Poecilia formosa ENSPFOG00000006677 I 0.870
ENSPFOG00000007171 Poecilia formosa ENSPFOG00000007171 I 0.870
ENSPMAG00000004927 Petromyzon marinus ENSPMAG00000004927 I 0.870
ENSPPYG00000013725 Pongo abelii ENSPPYG00000013725 I 0.870
ENSPSIG00000012120 Pelodiscus sinensis ENSPSIG00000012120 I 0.870
MITF Pan troglodytes ENSPTRG00000015100 I 0.870
Mitf Rattus norvegicus ENSRNOG00000008658 I 0.870
Tfe3 Rattus norvegicus ENSRNOG00000009605 I 0.870
MITF Sorex araneus ENSSARG00000002538 I 0.870
ENSSHAG00000017522 Sarcophilus harrisii ENSSHAG00000017522 I 0.870
ENSSTOG00000014237 Ictidomys tridecemlineatus ENSSTOG00000014237 I 0.870
MITF Tupaia belangeri ENSTBEG00000017713 I 0.870
MITF Taeniopygia guttata ENSTGUG00000009847 I 0.870
mitfa Tetraodon nigroviridis ENSTNIG00000007360 I 0.870
mitfb Tetraodon nigroviridis ENSTNIG00000012564 I 0.870
mitfa Takifugu rubripes ENSTRUG00000001600 I 0.870
mitfb Takifugu rubripes ENSTRUG00000012080 I 0.870
ENSTSYG00000011324 Tarsius syrichta ENSTSYG00000011324 I 0.870
MITF Tursiops truncatus ENSTTRG00000007072 I 0.870
ENSXMAG00000002200 Xiphophorus maculatus ENSXMAG00000002200 I 0.870
ENSXMAG00000016472 Xiphophorus maculatus ENSXMAG00000016472 I 0.870
Aan_R007225 Calypte anna Aan_R007225 I 0.870
Afo_R011673 Aptenodytes forsteri Afo_R011673 I 0.870
Alligator_sinensis_CCG002397.1 Alligator sinensis Alligator_sinensis_CCG002397.1 I 0.870
Alligator_sinensis_CCG004214.1 Alligator sinensis Alligator_sinensis_CCG004214.1 I 0.870
Brh_R009446 Buceros rhinoceros Brh_R009446 I 0.870
ENSBTAP00000053693-D1 Bos grunniens ENSBTAP00000053693-D1 I 0.870
ENSP00000391803 Macaca fascicularis ENSP00000391803 I 0.870
Gfo_R014572 Geospiza fortis Gfo_R014572 I 0.870
Myotis_brandtii_Mitf_10022588 Myotis brandtii Myotis_brandtii_Mitf_10022588 I 0.870
Pvit_00330 Pogona vitticeps Pvit_00330 I 0.870
Pvit_01233 Pogona vitticeps Pvit_01233 I 0.870
Tal_R001329 Tyto alba Tal_R001329 I 0.870
mitf Xenopus tropicalis XB-GENE-484962 I 0.870
mitf.L Xenopus laevis XB-GENE-6252679 I 0.870
mitf.S Xenopus laevis XB-GENE-6464338 I 0.870
TFE3 Monodelphis domestica ENSMODG00000009925 I 0.857