SIM1 (Homo sapiens)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSG00000112246 T034263_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000262901 bHLH 2 52
ENSP00000358210 bHLH 2 52

Links

Other bHLH family TFs
Other Homo sapiens TFs

195 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
SIM1 Anolis carolinensis ENSACAG00000010256 N 0.914
ENSAMEG00000014765 Ailuropoda melanoleuca ENSAMEG00000014765 N 0.914
ENSAMXG00000001377 Astyanax mexicanus ENSAMXG00000001377 N 0.914
ENSAPLG00000012534 Anas platyrhynchos ENSAPLG00000012534 N 0.914
SIM1 Bos taurus ENSBTAG00000002294 N 0.914
SIM1 Canis familiaris ENSCAFG00000003538 N 0.914
SIM1 Choloepus hoffmanni ENSCHOG00000005099 N 0.914
SIM1 Callithrix jacchus ENSCJAG00000001495 N 0.914
SIM1 Cavia porcellus ENSCPOG00000013987 N 0.914
ENSCSAG00000014652 Chlorocebus sabaeus ENSCSAG00000014652 N 0.914
sim1a Danio rerio ENSDARG00000023316 N 0.914
SIM1 Dasypus novemcinctus ENSDNOG00000010261 N 0.914
ENSDORG00000008569 Dipodomys ordii ENSDORG00000008569 N 0.914
SIM1 Equus caballus ENSECAG00000009161 N 0.914
SIM1 Erinaceus europaeus ENSEEUG00000009806 N 0.914
SIM1 Echinops telfairi ENSETEG00000010692 N 0.914
ENSFALG00000005247 Ficedula albicollis ENSFALG00000005247 N 0.914
SIM1 Felis catus ENSFCAG00000005942 N 0.914
sim1b Gasterosteus aculeatus ENSGACG00000009479 N 0.914
sim1a Gasterosteus aculeatus ENSGACG00000014149 N 0.914
SIM1 Gallus gallus ENSGALG00000015466 N 0.914
SIM1 Gorilla gorilla ENSGGOG00000017108 N 0.914
ENSGMOG00000006637 Gadus morhua ENSGMOG00000006637 N 0.914
ENSGMOG00000018211 Gadus morhua ENSGMOG00000018211 N 0.914
ENSLACG00000015924 Latimeria chalumnae ENSLACG00000015924 N 0.914
SIM1 Loxodonta africana ENSLAFG00000006594 N 0.914
ENSLOCG00000016561 Lepisosteus oculatus ENSLOCG00000016561 N 0.914
ENSMEUG00000011682 Macropus eugenii ENSMEUG00000011682 N 0.914
SIM1 Microcebus murinus ENSMICG00000008851 N 0.914
SIM1 Myotis lucifugus ENSMLUG00000002874 N 0.914
SIM1 Macaca mulatta ENSMMUG00000022285 N 0.914
SIM1 Monodelphis domestica ENSMODG00000018087 N 0.914
ENSMPUG00000001668 Mustela putorius furo ENSMPUG00000001668 N 0.914
Sim1 Mus musculus ENSMUSG00000019913 N 0.914
ENSNLEG00000013870 Nomascus leucogenys ENSNLEG00000013870 N 0.914
SIM1 Ornithorhynchus anatinus ENSOANG00000008943 N 0.914
ENSOARG00000011739 Ovis aries ENSOARG00000011739 N 0.914
SIM1 Oryctolagus cuniculus ENSOCUG00000002759 N 0.914
SIM1 Otolemur garnettii ENSOGAG00000009865 N 0.914
ENSONIG00000014696 Oreochromis niloticus ENSONIG00000014696 N 0.914
ENSONIG00000016544 Oreochromis niloticus ENSONIG00000016544 N 0.914
SIM1 Ochotona princeps ENSOPRG00000013168 N 0.914
ENSPANG00000011218 Papio anubis ENSPANG00000011218 N 0.914
SIM1 Procavia capensis ENSPCAG00000008763 N 0.914
ENSPPYG00000016868 Pongo abelii ENSPPYG00000016868 N 0.914
ENSPSIG00000002579 Pelodiscus sinensis ENSPSIG00000002579 N 0.914
SIM1 Pan troglodytes ENSPTRG00000018447 N 0.914
SIM1 Pteropus vampyrus ENSPVAG00000012822 N 0.914
Sim1 Rattus norvegicus ENSRNOG00000037600 N 0.914
SIM1 Sorex araneus ENSSARG00000000736 N 0.914
ENSSHAG00000016220 Sarcophilus harrisii ENSSHAG00000016220 N 0.914
SIM1 Sus scrofa ENSSSCG00000004357 N 0.914
ENSSTOG00000027359 Ictidomys tridecemlineatus ENSSTOG00000027359 N 0.914
SIM1 Tupaia belangeri ENSTBEG00000005949 N 0.914
SIM1 Taeniopygia guttata ENSTGUG00000012278 N 0.914
sim1b Tetraodon nigroviridis ENSTNIG00000012304 N 0.914
ENSTNIG00000019722 Tetraodon nigroviridis ENSTNIG00000019722 N 0.914
sim1b Takifugu rubripes ENSTRUG00000018267 N 0.914
ENSTSYG00000007116 Tarsius syrichta ENSTSYG00000007116 N 0.914
SIM1 Tursiops truncatus ENSTTRG00000008248 N 0.914
SIM1 Vicugna pacos ENSVPAG00000001407 N 0.914
ENSXMAG00000019075 Xiphophorus maculatus ENSXMAG00000019075 N 0.914
Aan_R007898 Calypte anna Aan_R007898 N 0.914
Afo_R003668 Aptenodytes forsteri Afo_R003668 N 0.914
Alligator_sinensis_CCG004879.1 Alligator sinensis Alligator_sinensis_CCG004879.1 N 0.914
Brh_R001528 Buceros rhinoceros Brh_R001528 N 0.914
Cmyd_10020168 Chelonia mydas Cmyd_10020168 N 0.914
ENSP00000262901 Macaca fascicularis ENSP00000262901 N 0.914
ENSP00000358210-D1 Bos grunniens ENSP00000358210-D1 N 0.914
Gfo_R003852 Geospiza fortis Gfo_R003852 N 0.914
Myotis_brandtii_SIM1_10034719 Myotis brandtii Myotis_brandtii_SIM1_10034719 N 0.914
Ogr12757 Ophisaurus gracilis Ogr12757 N 0.914
Pvit_09298 Pogona vitticeps Pvit_09298 N 0.914
sim1 Xenopus tropicalis XB-GENE-485816 N 0.914
sim1b Danio rerio ENSDARG00000013789 N 0.903
SIM1 Takifugu rubripes ENSTRUG00000010040 N 0.903
ENSAMXG00000008897 Astyanax mexicanus ENSAMXG00000008897 N 0.894
RPRC001595 Rhodnius prolixus RPRC001595 N 0.894
Smp_165270 Schistosoma mansoni Smp_165270 N 0.894
tetur06g06010 Tetranychus urticae tetur06g06010 N 0.894
Tal_R009812 Tyto alba Tal_R009812 N 0.894
Sjc_0126700 Schistosoma japonicum Sjc_0126700 N 0.894
A_05788 Schistosoma haematobium A_05788 N 0.894
csin104979 Clonorchis sinensis csin104979 N 0.894
D915_00831 Fasciola hepatica D915_00831 N 0.894
PXEA_0002490601 Protopolystoma xenopodis PXEA_0002490601 N 0.894
SMRZ_0000943001 Schistosoma margrebowiei SMRZ_0000943001 N 0.894
SMTD_0000610501 Schistosoma mattheei SMTD_0000610501 N 0.894
SROB_0001806001 Schistosoma rodhaini SROB_0001806001 N 0.894
T265_14441 Opisthorchis viverrini T265_14441 N 0.894
TRE_0000325801 Trichobilharzia regenti TRE_0000325801 N 0.894
ENSPFOG00000002603 Poecilia formosa ENSPFOG00000002603 N 0.882
ENSXMAG00000016785 Xiphophorus maculatus ENSXMAG00000016785 N 0.882
AGAP000773 Anopheles gambiae AGAP000773 N 0.862
CGI_10023142 Crassostrea gigas CGI_10023142 N 0.862
SIM2 Anolis carolinensis ENSACAG00000008765 N 0.862
ENSAMEG00000005588 Ailuropoda melanoleuca ENSAMEG00000005588 N 0.862
ENSAPLG00000014050 Anas platyrhynchos ENSAPLG00000014050 N 0.862
SIM2 Canis familiaris ENSCAFG00000009686 N 0.862
SIM2 Callithrix jacchus ENSCJAG00000002704 N 0.862
SIM2 Cavia porcellus ENSCPOG00000023156 N 0.862
ENSCSAG00000008567 Chlorocebus sabaeus ENSCSAG00000008567 N 0.862
SIM2 Dasypus novemcinctus ENSDNOG00000003669 N 0.862
Sim2 Dipodomys ordii ENSDORG00000011548 N 0.862
SIM2 Equus caballus ENSECAG00000016631 N 0.862
SIM2 Echinops telfairi ENSETEG00000012055 N 0.862
SIM2 Felis catus ENSFCAG00000023063 N 0.862
SIM2 Homo sapiens ENSG00000159263 N 0.862
SIM2 Gallus gallus ENSGALG00000016044 N 0.862
SIM2 Gorilla gorilla ENSGGOG00000014943 N 0.862
ENSLACG00000012873 Latimeria chalumnae ENSLACG00000012873 N 0.862
SIM2 Loxodonta africana ENSLAFG00000000122 N 0.862
ENSLOCG00000005059 Lepisosteus oculatus ENSLOCG00000005059 N 0.862
SIM2 Microcebus murinus ENSMICG00000013168 N 0.862
ENSMMUG00000015564 Macaca mulatta ENSMMUG00000015564 N 0.862
SIM2 Monodelphis domestica ENSMODG00000021008 N 0.862
ENSMPUG00000008240 Mustela putorius furo ENSMPUG00000008240 N 0.862
Sim2 Mus musculus ENSMUSG00000062713 N 0.862
ENSNLEG00000004481 Nomascus leucogenys ENSNLEG00000004481 N 0.862
ENSOARG00000014072 Ovis aries ENSOARG00000014072 N 0.862
SIM2 Oryctolagus cuniculus ENSOCUG00000012903 N 0.862
SIM2 Otolemur garnettii ENSOGAG00000028990 N 0.862
ENSPANG00000020491 Papio anubis ENSPANG00000020491 N 0.862
SIM2 Procavia capensis ENSPCAG00000015289 N 0.862
ENSPPYG00000011405 Pongo abelii ENSPPYG00000011405 N 0.862
SIM2 Pan troglodytes ENSPTRG00000013894 N 0.862
SIM2 Pteropus vampyrus ENSPVAG00000000853 N 0.862
Sim2 Rattus norvegicus ENSRNOG00000054203 N 0.862
ENSSHAG00000009425 Sarcophilus harrisii ENSSHAG00000009425 N 0.862
SIM2 Tupaia belangeri ENSTBEG00000011573 N 0.862
SIM2 Taeniopygia guttata ENSTGUG00000004856 N 0.862
ENSTSYG00000005255 Tarsius syrichta ENSTSYG00000005255 N 0.862
SIM2 Tursiops truncatus ENSTTRG00000017084 N 0.862
HelroG89969 Helobdella robusta HelroG89969 N 0.862
L798_01260 Zootermopsis nevadensis L798_01260 N 0.862
LotgiG106747 Lottia gigantea LotgiG106747 N 0.862
PHUM080130 Pediculus humanus PHUM080130 N 0.862
SMAR001482 Strigamia maritima SMAR001482 N 0.862
SPU_013962 Strongylocentrotus purpuratus SPU_013962 N 0.862
Aan_R007307 Calypte anna Aan_R007307 N 0.862
Afo_R004895 Aptenodytes forsteri Afo_R004895 N 0.862
Cmyd_10005300 Chelonia mydas Cmyd_10005300 N 0.862
ENSP00000290399-D1 Bos grunniens ENSP00000290399-D1 N 0.862
ENSP00000290399 Macaca fascicularis ENSP00000290399 N 0.862
Gfo_R010900 Geospiza fortis Gfo_R010900 N 0.862
Pvit_04770 Pogona vitticeps Pvit_04770 N 0.862
estExt_GenewiseH_1.C_790104 Branchiostoma floridae estExt_GenewiseH_1.C_790104 N 0.862
Ocbimv22031168m.g Octopus bimaculoides Ocbimv22031168m.g N 0.862
sim2.S Xenopus laevis XB-GENE-1013959 N 0.862
XP_002941575 Xenopus tropicalis XP_002941575 N 0.862
AARA010261 Anopheles arabiensis AARA010261 N 0.862
ACHR009289 Anopheles christyi ACHR009289 N 0.862
ACOM042361 Anopheles coluzzii ACOM042361 N 0.862
ACUA010023 Anopheles culicifacies ACUA010023 N 0.862
AEPI002639 Anopheles epiroticus AEPI002639 N 0.862
AFUN005600 Anopheles funestus AFUN005600 N 0.862
AMAM016994 Anopheles maculatus AMAM016994 N 0.862
AMEC013102 Anopheles melas AMEC013102 N 0.862
AMIN005129 Anopheles minimus AMIN005129 N 0.862
AQUA008255 Anopheles quadriannulatus AQUA008255 N 0.862
ASTEI03596 Anopheles stephensi ASTEI03596 N 0.862
ENSMEUG00000000606 Macropus eugenii ENSMEUG00000000606 N 0.858
NPAS1 Monodelphis domestica ENSMODG00000009053 N 0.858
HelroG158226 Helobdella robusta HelroG158226 N 0.851
NV16594 Nasonia vitripennis NV16594 I 0.851
SMU15015785 Schmidtea mediterranea SMU15015785 N 0.851
SPER_0003947801 Spirometra erinaceieuropaei SPER_0003947801 N 0.851
CapteG165634 Capitella teleta CapteG165634 I 0.840
CpipJ_CPIJ009948 Culex pipiens CpipJ_CPIJ009948 I 0.838
AAEL011013 Aedes aegypti AAEL011013 I 0.838
ADAC005208 Anopheles darlingi ADAC005208 I 0.838
AGAP010058 Anopheles gambiae AGAP010058 I 0.838
BGIBMGA003821 Bombyx mori BGIBMGA003821 I 0.838
CPIJ009948 Culex quinquefasciatus CPIJ009948 I 0.838
DAPPUDRAFT_311851 Daphnia pulex DAPPUDRAFT_311851 I 0.838
HMEL008134 Heliconius melpomene HMEL008134 I 0.838
KGM_03494 Danaus plexippus KGM_03494 I 0.838
LCUP006648 Lucilia cuprina LCUP006648 I 0.838
AALB007758 Anopheles albimanus AALB007758 I 0.838
AALB007964 Anopheles albimanus AALB007964 I 0.838
AARA003714 Anopheles arabiensis AARA003714 I 0.838
AATE009363 Anopheles atroparvus AATE009363 I 0.838
ACOM023265 Anopheles coluzzii ACOM023265 I 0.838
ACOM027359 Anopheles coluzzii ACOM027359 I 0.838
ACUA025040 Anopheles culicifacies ACUA025040 I 0.838
ADIR001121 Anopheles dirus ADIR001121 I 0.838
AFAF010850 Anopheles farauti AFAF010850 I 0.838
AFUN000102 Anopheles funestus AFUN000102 I 0.838
AMEC021622 Anopheles melas AMEC021622 I 0.838
AMEM005407 Anopheles merus AMEM005407 I 0.838
AMIN006671 Anopheles minimus AMIN006671 I 0.838
AQUA009218 Anopheles quadriannulatus AQUA009218 I 0.838
ASTEI03921 Anopheles stephensi ASTEI03921 I 0.838
MDOA008891 Musca domestica MDOA008891 I 0.838