EPAS1 (Homo sapiens)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSG00000116016 T034267_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
EPAS1
M08719_2.00		 Homo sapiens
VDACGTGMN
NKCACGTHB		 Misc
Kulakovskiy et al.(2013)
EPAS1_HUMAN.H11MO.0.B		 (Direct) (Direct)
EPAS1
M09455_2.00		 Homo sapiens
KCACGTMBNH
DNVKACGTGM		 Misc
Heinz et al.(2010)
785_O-HIF2a_GSE34871		 (Direct) (Direct)
EPAS1
M09826_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HIF2A_01		 (Direct) (Direct)
EPAS1
M09827_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HIF2A_Q6		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000263734 bHLH 15 68
ENSP00000406137 bHLH 15 68

Links

Other bHLH family TFs
Other Homo sapiens TFs

5 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
Epas1 Dipodomys ordii ENSDORG00000003635 I 0.914
Tal_R006997 Tyto alba Tal_R006997 I 0.861
ENSTNIG00000019821 Tetraodon nigroviridis ENSTNIG00000019821 I 0.858
epas1.L Xenopus laevis XB-GENE-981617 I 0.843