Met (Drosophila melanogaster)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 FBgn0002723 T038397_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables nuclear receptor activity and protein heterodimerization activity. Involved in negative regulation of programmed cell death; positive regulation of transcription by RNA polymerase II; and regulation of developmental process. Located in nucleus. Is expressed in several structures, including embryonic/larval gut; gland; larval imaginal tissue; reproductive system; and supraesophageal ganglion. [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Met
M05943_2.00
Drosophila melanogaster
CACGTGKM

KACACGTG
B1H
Zhu et al.(2011)
Met_Clk_SANGER_5_FBgn0002723
(Direct) (Direct)
Met
M05944_2.00
Drosophila melanogaster
MCACGTG

CACGTGK
B1H
Zhu et al.(2011)
Met_SANGER_5_FBgn0002723
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
FBpp0073368 bHLH 37 88
FBpp0310182 bHLH 37 88

Links

Other bHLH family TFs
Other Drosophila melanogaster TFs

8 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
GM13098 Drosophila sechellia FBgn0168029 I 0.914
GD17037 Drosophila simulans FBgn0188611 I 0.914
GE15657 Drosophila yakuba FBgn0233227 I 0.914
GL13106 Drosophila persimilis FBgn0150712 I 0.914
GG18435 Drosophila erecta FBgn0110650 I 0.914
GA14297 Drosophila pseudoobscura FBgn0074325 I 0.914
GF19442 Drosophila ananassae FBgn0096451 I 0.914