hlh-27 (Caenorhabditis elegans)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 WBGene00001966 T046289_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anterior/posterior pattern specification; regulation of neurogenesis; and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including ABpla; ABplp; ABpra; ABprp; and MS. [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
HLH27
M00928_2.00 		Caenorhabditis elegans
CGCRTGKC
GMCAYGCG		 PBM
Grove et al.(2009)
HLH27 		0.914 1.000
hlh-25
M00932_2.00 		Caenorhabditis elegans
CGCRTGKB
VMCAYGCG		 PBM
Grove et al.(2009)
HLH25 		0.914 0.990
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
C17C3.10 bHLH 20 66
C17C3.10 bHLH 93 150

Links

Other bHLH family TFs
Other Caenorhabditis elegans TFs

2 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
hlh-25 Caenorhabditis elegans WBGene00001964 D 0.914
HLH27 Caenorhabditis elegans HLH27 D 0.914