HMS1 (Saccharomyces cerevisiae)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 YOR032C T046370_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity. Involved in pseudohyphal growth. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in carotid artery disease; prostate cancer; type 1 diabetes mellitus; type 2 diabetes mellitus; and vascular dementia. Orthologous to human SREBF2 (sterol regulatory element binding transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
HMS1
M08488_2.00
Saccharomyces cerevisiae
HCACGTMV

BKACGTGD
Misc
DeBoer et al.(2011)
YOR032C_1498
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
YOR032C bHLH 267 342

Links

Other bHLH family TFs
Other Saccharomyces cerevisiae TFs

14 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
SU7_3203 Saccharomyces arboricola SU7_3203 I 0.914
20073_Multiple Saccharomyces mikatae 20073_Multiple I 0.914
23114_YOR032C Saccharomyces bayanus 23114_YOR032C I 0.914
20426_YOR032C Saccharomyces paradoxus 20426_YOR032C I 0.903
ZBAI_08029 Zygosaccharomyces bailii ZBAI_08029 I 0.890
SAKL0G07282g Lachancea kluyveri SAKL0G07282g I 0.890
ZBAI_02175 Zygosaccharomyces bailii ZBAI_02175 I 0.890
KLTH0E02376g Kluyveromyces thermotolerans KLTH0E02376g I 0.864
Ecym_1333 Eremothecium cymbalariae Ecym_1333 I 0.864
KLTH0E02376g Lachancea thermotolerans KLTH0E02376g I 0.864
TDEL_0A04900 Torulaspora delbrueckii TDEL_0A04900 I 0.860
AGOS_AER385C Ashbya gossypii AGOS_AER385C I 0.860
LALA0_S05e02850g Lachancea lanzarotensis LALA0_S05e02850g I 0.860
AACERI_AaceriAER385C Saccharomycetaceae sp ashbya aceri AACERI_AaceriAER385C I 0.860