TYE7 (Saccharomyces cerevisiae)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 YOR344C T046371_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables DNA-binding transcription factor activity. Involved in positive regulation of glycolytic process and transcription elongation from RNA polymerase II promoter. Located in chromatin. Human ortholog(s) of this gene implicated in cardiovascular system disease; disease of metabolism; and type 2 diabetes mellitus. Orthologous to human SREBF1 (sterol regulatory element binding transcription factor 1) and USF1 (upstream transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
TYE7
M00011_2.00		 Saccharomyces cerevisiae
VTCACGTG
CACGTGAB		 PBM
Badis et al.(2008)
TYE7_2097		 (Direct) (Direct)
TYE7
M01521_2.00		 Saccharomyces cerevisiae
NRYCASSTGD
HCASSTGRYN		 PBM
Zhu et al.(2009)
Tye7		 (Direct) (Direct)
TYE7
M07441_2.00		 Saccharomyces cerevisiae
TCACGTG
CACGTGA		 PBM, CSA and or DIP-chip
Mathelier et al.(2014)
MA0409.1		 (Direct) (Direct)
TYE7
M08489_2.00		 Saccharomyces cerevisiae
RTCACGTGA
TCACGTGAY		 Misc
DeBoer et al.(2011)
YOR344C_397		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.838 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00011_2.00 bHLH 51 136
M01521_2.00 bHLH 181 266

DNA Binding Domains

Protein ID Domain From To Sequence
YOR344C bHLH 181 266

Links

Other bHLH family TFs
Other Saccharomyces cerevisiae TFs

15 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
SKUD_194503 Saccharomyces kudriavzevii SKUD_194503 I 0.914
SU7_3407 Saccharomyces arboricola SU7_3407 I 0.914
20702_YOR344C Saccharomyces mikatae 20702_YOR344C I 0.914
24252_YOR344C Saccharomyces bayanus 24252_YOR344C I 0.914
Ecym_5051 Eremothecium cymbalariae Ecym_5051 I 0.886
SAKL0B10868g Lachancea kluyveri SAKL0B10868g I 0.886
21560_YOR344C Saccharomyces paradoxus 21560_YOR344C I 0.871
Kwal_6961 Kluyveromyces waltii Kwal_6961 I 0.861
KLTH0D01540g Kluyveromyces thermotolerans KLTH0D01540g I 0.861
TDEL_0H04040 Torulaspora delbrueckii TDEL_0H04040 I 0.861
KLTH0D01540g Lachancea thermotolerans KLTH0D01540g I 0.861
KAFR_0C05180 Kazachstania africana KAFR_0C05180 I 0.859
KAFR_0K00520 Kazachstania africana KAFR_0K00520 I 0.859
ZYRO0D04642g Zygosaccharomyces rouxii ZYRO0D04642g I 0.846
KNAG_0E00420 Kazachstania naganishii KNAG_0E00420 I 0.838