XBP1 (Homo sapiens)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00170 (bZIP_1) IPR011616 ENSG00000100219 T059725_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
XBP1
M02730_2.00		 Homo sapiens
GACGTGKCNNW
WNNGMCACGTC		 SELEX
Jolma et al.(2010)
XBP1_monomer		 (Direct) (Direct)
XBP1
M02825_2.00		 Homo sapiens
GVTGACGTCABB
VVTGACGTCABC		 SELEX
Jolma et al.(2013)
XBP1_1		 (Direct) (Direct)
XBP1
M02826_2.00		 Homo sapiens
GVTGACGTGKCVHW
WDBGMCACGTCABC		 SELEX
Jolma et al.(2013)
XBP1_2		 (Direct) (Direct)
XBP1
M04010_2.00		 Homo sapiens
GRTGACGTGKCV
BGMCACGTCAYC		 SELEX
Rodriguez-Martinez et al.(2017)
XBP1.1		 (Direct) (Direct)
XBP1
M04011_2.00		 Homo sapiens
GRTGACGTCAYS
SRTGACGTCAYC		 SELEX
Rodriguez-Martinez et al.(2017)
XBP1.2		 (Direct) (Direct)
XBP1
M04012_2.00		 Homo sapiens
KGMCACGTGKMCH
DGKMCACGTGKCM		 SELEX
Rodriguez-Martinez et al.(2017)
XBP1.3		 (Direct) (Direct)
XBP1
M04231_2.00		 Homo sapiens
NVTGACGTGKNN
NNMCACGTCABN		 SELEX
Yin et al.(2017)
XBP1_FL_HT-SELEX_1		 (Direct) (Direct)
XBP1
M04232_2.00		 Homo sapiens
NVTKACGTMABV
BVTKACGTMABN		 SELEX
Yin et al.(2017)
XBP1_FL_HT-SELEX_2		 (Direct) (Direct)
XBP1
M04233_2.00		 Homo sapiens
BKMCACRTCAYS
SRTGAYGTGKMV		 SELEX
Yin et al.(2017)
XBP1_FL_Methyl-HT-SELEX_1		 (Direct) (Direct)
XBP1
M04234_2.00		 Homo sapiens
VVTGWCRTCAYS
SRTGAYGWCABB		 SELEX
Yin et al.(2017)
XBP1_FL_Methyl-HT-SELEX_2		 (Direct) (Direct)
XBP1
M09932_2.00		 Homo sapiens
NHNWDHRVTGACGTGKHNHWDDHB
VDHHWDNDMCACGTCABYDHWNDN		 Transfac
Matys et al.(2006)
V$HTF_01		 (Direct) (Direct)
XBP1
M09933_2.00		 Homo sapiens
DBRHTKACGTGKHNHWD
HWDNDMCACGTMADYVH		 Transfac
Matys et al.(2006)
V$XBP1_01		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Xbp1
M00757_2.00 		Mus musculus
NNHBAYDNNN
NNNHRTVDNN		 PBM
Weirauch et al.(2013)
pTH2852 		0.872 0.969
Xbp1
M01802_2.00 		Mus musculus
NHNACGYNN
NNRCGTNDN		 PBM
Weirauch et al.(2014)
pTH5019 		0.872 0.969
Xbp1
M08818_2.00 		Mus musculus
GACGTGKCMHWD
HWDKGMCACGTC		 Misc
Kulakovskiy et al.(2013)
XBP1_MOUSE.H11MO.0.C 		0.872 0.969
For this family, TFs with SR scores > 0.782 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000216037 bZIP 68 131
ENSP00000343155 bZIP 68 131
ENSP00000384295 bZIP 19 81
ENSP00000385162 bZIP 68 142
ENSP00000481170 bZIP 68 131

Links

Other bZIP family TFs
Other Homo sapiens TFs

59 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
XBP1 Bos taurus ENSBTAG00000005970 I 0.872
ENSCAFG00000011954 Canis familiaris ENSCAFG00000011954 I 0.872
XBP1 Cavia porcellus ENSCPOG00000007796 I 0.872
ENSCSAG00000009947 Chlorocebus sabaeus ENSCSAG00000009947 I 0.872
XBP1 Equus caballus ENSECAG00000014780 I 0.872
XBP1 Gorilla gorilla ENSGGOG00000007154 I 0.872
XBP1 Microcebus murinus ENSMICG00000004235 I 0.872
ENSMLUG00000001735 Myotis lucifugus ENSMLUG00000001735 I 0.872
XBP1 Macaca mulatta ENSMMUG00000007215 I 0.872
ENSMPUG00000013524 Mustela putorius furo ENSMPUG00000013524 I 0.872
Xbp1 Mus musculus ENSMUSG00000020484 D 0.872
ENSNLEG00000002404 Nomascus leucogenys ENSNLEG00000002404 I 0.872
ENSOARG00000002962 Ovis aries ENSOARG00000002962 I 0.872
ENSOPRG00000013983 Ochotona princeps ENSOPRG00000013983 I 0.872
ENSPANG00000000372 Papio anubis ENSPANG00000000372 I 0.872
ENSPPYG00000011678 Pongo abelii ENSPPYG00000011678 I 0.872
XBP1 Pan troglodytes ENSPTRG00000014210 I 0.872
ENSPVAG00000004528 Pteropus vampyrus ENSPVAG00000004528 I 0.872
Xbp1 Rattus norvegicus ENSRNOG00000010298 I 0.872
XBP1 Sorex araneus ENSSARG00000002418 I 0.872
XBP1 Loxodonta africana ENSLAFG00000029029 I 0.868
ENSTSYG00000000515 Tarsius syrichta ENSTSYG00000000515 I 0.864
ENSLOCG00000003156 Lepisosteus oculatus ENSLOCG00000003156 I 0.863
ENSSHAG00000010795 Sarcophilus harrisii ENSSHAG00000010795 I 0.862
ENSGMOG00000000538 Gadus morhua ENSGMOG00000000538 I 0.861
xbp1 Xenopus tropicalis XB-GENE-487124 I 0.857
xbp1.L Xenopus laevis XB-GENE-487128 I 0.857
ENSFALG00000008312 Ficedula albicollis ENSFALG00000008312 I 0.853
XBP1 Taeniopygia guttata ENSTGUG00000007938 I 0.853
Aan_R010399 Calypte anna Aan_R010399 I 0.853
ENSONIG00000010547 Oreochromis niloticus ENSONIG00000010547 I 0.849
ENSPFOG00000014555 Poecilia formosa ENSPFOG00000014555 I 0.849
XBP1 Tetraodon nigroviridis ENSTNIG00000015621 I 0.849
xbp1 Takifugu rubripes ENSTRUG00000016185 I 0.849
ENSXMAG00000002665 Xiphophorus maculatus ENSXMAG00000002665 I 0.849
ENSAMXG00000004136 Astyanax mexicanus ENSAMXG00000004136 I 0.848
xbp1 Gasterosteus aculeatus ENSGACG00000014266 I 0.848
ENSMODG00000023331 Monodelphis domestica ENSMODG00000023331 I 0.848
xbp1 Danio rerio ENSDARG00000035622 I 0.847
AAI60967 Xenopus tropicalis AAI60967 I 0.847
ENSCHOG00000011608 Choloepus hoffmanni ENSCHOG00000011608 I 0.844
ENSPANG00000007517 Papio anubis ENSPANG00000007517 N 0.834
XBP1 Gallus gallus ENSGALG00000005796 I 0.832
ENSAMEG00000008458 Ailuropoda melanoleuca ENSAMEG00000008458 I 0.830
ENSDNOG00000034497 Dasypus novemcinctus ENSDNOG00000034497 I 0.830
ENSFCAG00000028366 Felis catus ENSFCAG00000028366 I 0.830
XBP1 Ornithorhynchus anatinus ENSOANG00000008817 I 0.830
ENSOCUG00000006928 Oryctolagus cuniculus ENSOCUG00000006928 I 0.830
ENSSTOG00000004168 Ictidomys tridecemlineatus ENSSTOG00000004168 I 0.830
ENSMMUP00000009460 Macaca fascicularis ENSMMUP00000009460 I 0.830
ENSP00000343155-D2 Bos grunniens ENSP00000343155-D2 I 0.830
Myotis_brandtii_XBP1_10027497 Myotis brandtii Myotis_brandtii_XBP1_10027497 I 0.830
NEMVEDRAFT_v1g211292 Nematostella vectensis NEMVEDRAFT_v1g211292 I 0.827
XBP1 Callithrix jacchus ENSCJAG00000020084 I 0.826
ENSTBEG00000000324 Tupaia belangeri ENSTBEG00000000324 I 0.815
Pvit_02423 Pogona vitticeps Pvit_02423 I 0.811
XBP1 Procavia capensis ENSPCAG00000004565 N 0.796
ENSMGAG00000007147 Meleagris gallopavo ENSMGAG00000007147 I 0.789