Creb3 (Mus musculus)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00170 (bZIP_1) IPR011616 ENSMUSG00000028466 T060472_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables sequence-specific DNA binding activity. Predicted to be involved in several processes, including positive regulation of defense response to virus by host; positive regulation of monocyte chemotaxis; and regulation of transcription, DNA-templated. Predicted to act upstream of or within chemotaxis and response to unfolded protein. Predicted to be located in several cellular components, including Golgi membrane; neuronal cell body; and nuclear body. Predicted to be integral component of endoplasmic reticulum membrane. Predicted to be active in nucleus. Is expressed in several structures, including 1st branchial arch; central nervous system; early conceptus; genitourinary system; and skeleton. Orthologous to human CREB3 (cAMP responsive element binding protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Creb3
M10030_2.00		 Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$LUMAN_01		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
CREB3
M02829_2.00 		Homo sapiens
NNRTGACGTCAYCV
BGRTGACGTCAYNN		 SELEX
Jolma et al.(2013)
CREB3_1 		0.825 0.906
CREB3
M02830_2.00 		Homo sapiens
NDRTGACGTGKMVN
NBKMCACGTCAYHN		 SELEX
Jolma et al.(2013)
CREB3_2 		0.825 0.906
CREB3
M04239_2.00 		Homo sapiens
NRTGACGTGKHN
NDMCACGTCAYN		 SELEX
Yin et al.(2017)
CREB3_FL_HT-SELEX_1 		0.825 0.906
CREB3
M04240_2.00 		Homo sapiens
NDMCACGTGGYN
NRCCACGTGKHN		 SELEX
Yin et al.(2017)
CREB3_FL_HT-SELEX_2 		0.825 0.906
CREB3
M04241_2.00 		Homo sapiens
NRTGACGTCAYN
NRTGACGTCAYN		 SELEX
Yin et al.(2017)
CREB3_FL_HT-SELEX_3 		0.825 0.906
CREB3
M04014_2.00 		Homo sapiens
GRTGACGTGGMV
BKCCACGTCAYC		 SELEX
Rodriguez-Martinez et al.(2017)
CREB3.1 		0.825 0.906
CREB3
M04015_2.00 		Homo sapiens
VRTGACGTCACB
VGTGACGTCAYB		 SELEX
Rodriguez-Martinez et al.(2017)
CREB3.2 		0.825 0.906
CREB3
M04242_2.00 		Homo sapiens
NKMSACGTSGCV
BGCSACGTSKMN		 SELEX
Yin et al.(2017)
CREB3_FL_Methyl-HT-SELEX_1 		0.825 0.906
CREB3
M04243_2.00 		Homo sapiens
YKCCACRTCAYM
KRTGAYGTGGMR		 SELEX
Yin et al.(2017)
CREB3_FL_Methyl-HT-SELEX_2 		0.825 0.906
CREB3
M04244_2.00 		Homo sapiens
NRTGACRTCAYH
DRTGAYGTCAYN		 SELEX
Yin et al.(2017)
CREB3_FL_Methyl-HT-SELEX_3 		0.825 0.906
For this family, TFs with SR scores > 0.782 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000100008 bZIP 158 227
ENSMUSP00000129401 bZIP 182 251

Links

Other bZIP family TFs
Other Mus musculus TFs

8 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CREB3 Homo sapiens ENSG00000107175 D 0.825
ENSNLEG00000004179 Nomascus leucogenys ENSNLEG00000004179 I 0.823
CREB3 Dasypus novemcinctus ENSDNOG00000041334 I 0.806
Cmyd_10002091 Chelonia mydas Cmyd_10002091 I 0.798
Alligator_sinensis_CCG007409.1 Alligator sinensis Alligator_sinensis_CCG007409.1 I 0.794
Afo_R001188 Aptenodytes forsteri Afo_R001188 I 0.782
ENSGALG00000002523 Gallus gallus ENSGALG00000002523 I 0.782