atf-7 (Caenorhabditis elegans)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00170 (bZIP_1) IPR011616 WBGene00000223 T069396_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and mitogen-activated protein kinase binding activity. Involved in several processes, including defense response to bacterium; regulation of innate immune response; and regulation of transcription by RNA polymerase II. Acts upstream of or within serotonin biosynthetic process. Located in chromatin and nucleus. Is expressed in body wall musculature; hypodermis; intestine; neurons; and rectal epithelial cell. Orthologous to human ATF2 (activating transcription factor 2); ATF7 (activating transcription factor 7); and CREB5 (cAMP responsive element binding protein 5). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
atf-7
M00595_2.00		 Caenorhabditis elegans
NRTGACGTVN
NBACGTCAYN		 PBM
Narasimhan et al.(2015)
pTH9314		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
CBG18054
M01141_2.00 		Caenorhabditis briggsae
NRTGACGTSA
TSACGTCAYN		 PBM
Lambert et al.(2019)
pTH11475 		0.872 0.922
For this family, TFs with SR scores > 0.782 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00595_2.00 bZIP 52 113

DNA Binding Domains

Protein ID Domain From To Sequence
C07G2.2a bZIP 341 402
C07G2.2b bZIP 341 407
C07G2.2c.1 bZIP 390 456
C07G2.2c.2 bZIP 390 456
C07G2.2d.1 bZIP 322 372
C07G2.2d.2 bZIP 322 372

Links

Other bZIP family TFs
Other Caenorhabditis elegans TFs

52 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CBG18054 Caenorhabditis briggsae CBG18054 D 0.929
CBN12281 Caenorhabditis brenneri CBN12281 I 0.926
SVUK_0000294201 Strongylus vulgaris SVUK_0000294201 I 0.918
ANCDUO_04423 Ancylostoma duodenale ANCDUO_04423 I 0.918
HCOI00036200 Haemonchus contortus HCOI00036200 I 0.918
ANCCEY_04780 Ancylostoma ceylanicum ANCCEY_04780 I 0.905
OESDEN_14093 Oesophagostomum dentatum OESDEN_14093 I 0.905
ANCCAN_09146 Ancylostoma caninum ANCCAN_09146 I 0.905
CGOC_0000243701 Cylicostephanus goldi CGOC_0000243701 I 0.905
L898_g34193 Steinernema monticolum L898_g34193 I 0.902
L892_g20441 Steinernema scapterisci L892_g20441 I 0.899
L889_g21188 Steinernema feltiae L889_g21188 I 0.899
ACAC_0001181901 Angiostrongylus cantonensis ACAC_0001181901 I 0.899
L596_g6797 Steinernema carpocapsae L596_g6797 I 0.899
BTMF_0001510901 Brugia timori BTMF_0001510901 I 0.897
WUBG_08190 Wuchereria bancrofti WUBG_08190 I 0.897
Bm2053 Brugia malayi Bm2053 I 0.897
CRE20256 Caenorhabditis remanei CRE20256 I 0.894
CJA14314 Caenorhabditis japonica CJA14314 I 0.894
nOo.2.0.1.g05937 Onchocerca ochengi nOo.2.0.1.g05937 I 0.893
nLs.2.1.2.g00491 Litomosoides sigmodontis nLs.2.1.2.g00491 I 0.893
nDi.2.2.2.g07084 Dirofilaria immitis nDi.2.2.2.g07084 I 0.893
nAv.1.0.1.g05180 Acanthocheilonema viteae nAv.1.0.1.g05180 I 0.893
EEL_0000209901 Elaeophora elaphi EEL_0000209901 I 0.893
ASU_05203 Ascaris suum ASU_05203 I 0.893
ASIM_0001340801 Anisakis simplex ASIM_0001340801 I 0.893
WBGene00244485 Onchocerca volvulus WBGene00244485 I 0.893
TCLT_0000921801 Thelazia callipaeda TCLT_0000921801 I 0.893
OFLC_0000863501 Onchocerca flexuosa OFLC_0000863501 I 0.893
LOAG_06720 Loa loa LOAG_06720 I 0.893
NECAME_10658 Necator americanus NECAME_10658 I 0.891
BXY_1618500 Bursaphelenchus xylophilus BXY_1618500 I 0.889
Ppa-atf-7 Pristionchus pacificus PPA19791 I 0.887
scaffold12-EXSNAP2012.55 Pristionchus exspectatus scaffold12-EXSNAP2012.55 I 0.887
HPLM_0000438501 Haemonchus placei HPLM_0000438501 I 0.880
NBR_0000389301 Nippostrongylus brasiliensis NBR_0000389301 I 0.880
SPAL_0001020300 Strongyloides papillosus SPAL_0001020300 I 0.879
SSTP_0000122600 Strongyloides stercoralis SSTP_0000122600 I 0.879
SVE_0504300 Strongyloides venezuelensis SVE_0504300 I 0.879
PTRK_0000099300 Parastrongyloides trichosuri PTRK_0000099300 I 0.879
RSKR_0000227000 Rhabditophanes kr3021 RSKR_0000227000 I 0.865
TELCIR_01729 Teladorsagia circumcincta TELCIR_01729 I 0.863
Hba_12020 Heterorhabditis bacteriophora Hba_12020 I 0.863
SMUV_0000975301 Syphacia muris SMUV_0000975301 I 0.858
EVEC_0000278301 Enterobius vermicularis EVEC_0000278301 I 0.855
DME_0000565001 Dracunculus medinensis DME_0000565001 I 0.853
augustus_masked-nMf.1.1.scaf16754-processed-gene-0.0 Meloidogyne floridensis augustus_masked-nMf.1.1.scaf16754-processed-gene-0.0 I 0.851
MhA1_Contig342.frz3.gene59 Meloidogyne hapla MhA1_Contig342.frz3.gene59 I 0.851
HPBE_0000018301 Heligmosomoides bakeri HPBE_0000018301 I 0.844
PEQ_0000753901 Parascaris equorum PEQ_0000753901 I 0.835
TCNE_0001734401 Toxocara canis TCNE_0001734401 I 0.835