|
ENSP00000262053
(Macaca fascicularis)
bZIP
|
TF Information |
Pfam ID |
Interpro ID |
Gene ID |
CIS-BP ID |
Sequence source |
PF00170 (bZIP_1) |
IPR011616 |
ENSP00000262053 |
T070153_2.00 |
GigaDB (2015-Oct-22) |
NCBI Gene Info:This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6. [provided by RefSeq, Aug 2010] |
Directly determined binding motifs |
Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR Score |
DBD Identity |
No direct experiments |
|
|
|
|
|
Motifs from related TFs |
Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR Score |
DBD Identity |
ATF1
M08792_2.00 |
Homo sapiens |
HBRCGTCAYHN |
NDRTGACGYVD |
Misc
Kulakovskiy et al.(2013)
ATF1_HUMAN.H11MO.0.B
|
0.906
|
1.000
|
ATF1
M09485_2.00 |
Homo sapiens |
NVTGACGTMA |
TKACGTCABN |
Misc
Heinz et al.(2010)
K562-ATF1_GSE31477
|
0.906
|
1.000
|
ATF1
M09956_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$ATF1_Q3
|
0.906
|
1.000
|
ATF1
M09957_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$ATF1_Q6_01
|
0.906
|
1.000
|
ATF1
M09958_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$ATF1_Q6
|
0.906
|
1.000
|
Atf1
M00124_2.00 |
Mus musculus |
NNNNDNDNNN |
NNNHNHNNNN |
PBM
Badis et al.(2009)
Atf1_3026
|
0.896
|
0.967
|
Atf1
M01804_2.00 |
Mus musculus |
RTGACGTV |
BACGTCAY |
PBM
Weirauch et al.(2014)
pTH5005
|
0.896
|
0.967
|
Atf1
M08820_2.00 |
Mus musculus |
VTGACGTSAV |
BTSACGTCAB |
Misc
Kulakovskiy et al.(2013)
ATF1_MOUSE.H11MO.0.B
|
0.896
|
0.967
|
Creb1
M00992_2.00 |
Mus musculus |
NNTGACGTCV |
BGACGTCANN |
PBM
Mann et al.(2013)
CREB1_UM_HK
|
0.894
|
0.867
|
Creb1
M01806_2.00 |
Mus musculus |
VTKACGHNN |
NNDCGTMAB |
PBM
Weirauch et al.(2014)
pTH5080
|
0.894
|
0.867
|
CREB1
M04264_2.00 |
Homo sapiens |
NVTKACGTMABN |
NVTKACGTMABN |
SELEX
Yin et al.(2017)
CREB1_FL_HT-SELEX
|
0.894
|
0.867
|
CREB1
M04258_2.00 |
Homo sapiens |
NVTKACGTMANN |
NNTKACGTMABN |
SELEX
Yin et al.(2017)
CREB1_eDBD_HT-SELEX_1
|
0.894
|
0.867
|
CREB1
M04259_2.00 |
Homo sapiens |
NRTGACGTR |
YACGTCAYN |
SELEX
Yin et al.(2017)
CREB1_eDBD_HT-SELEX_2
|
0.894
|
0.867
|
CREB1
M04260_2.00 |
Homo sapiens |
VTSACRYGWBAY |
RTVWCRYGTSAB |
SELEX
Yin et al.(2017)
CREB1_eDBD_HT-SELEX_3
|
0.894
|
0.867
|
CREB1
M04022_2.00 |
Homo sapiens |
NRTGACGTCAYN |
NRTGACGTCAYN |
SELEX
Rodriguez-Martinez et al.(2017)
CREB1.1
|
0.894
|
0.867
|
CREB1
M04023_2.00 |
Homo sapiens |
RTGACGTADB |
VHTACGTCAY |
SELEX
Rodriguez-Martinez et al.(2017)
CREB1.2
|
0.894
|
0.867
|
CREB1
M08066_2.00 |
Homo sapiens |
NVTGACGTCABN |
NVTGACGTCABN |
ChIP-seq
Mathelier et al.(2014)
MA0018.3
|
0.894
|
0.867
|
CREB1
M08791_2.00 |
Homo sapiens |
WKRCGTCAYYN |
NRRTGACGYMW |
Misc
Kulakovskiy et al.(2013)
CREB1_HUMAN.H11MO.0.A
|
0.894
|
0.867
|
Creb1
M08824_2.00 |
Mus musculus |
WKRCGTCAYYN |
NRRTGACGYMW |
Misc
Kulakovskiy et al.(2013)
CREB1_MOUSE.H11MO.0.A
|
0.894
|
0.867
|
CREB1
M09948_2.00 |
Homo sapiens |
TGACGTMW |
WKACGTCA |
Transfac
Matys et al.(2006)
V$CREB_01
|
0.894
|
0.867
|
CREB1
M09949_2.00 |
Homo sapiens |
BBGDTGACGYVV |
BBRCGTCAHCVV |
Transfac
Matys et al.(2006)
V$CREB_02
|
0.894
|
0.867
|
CREB1
M09950_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$CREB1_Q3
|
0.894
|
0.867
|
CREB1
M09951_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$CREB1_Q6
|
0.894
|
0.867
|
CREB1
M09952_2.00 |
Homo sapiens |
BSTGACGYARNN |
NNYTRCGTCASV |
Transfac
Matys et al.(2006)
V$CREB_Q2
|
0.894
|
0.867
|
CREB1
M09953_2.00 |
Homo sapiens |
BSTGACGYMRBV |
BVYKRCGTCASV |
Transfac
Matys et al.(2006)
V$CREB_Q4
|
0.894
|
0.867
|
CREB1
M09954_2.00 |
Homo sapiens |
KKGGGKTGACGYMND |
HNKRCGTCAMCCCMM |
Transfac
Matys et al.(2006)
V$TAXCREB_01
|
0.894
|
0.867
|
CREB1
M09955_2.00 |
Homo sapiens |
RTGACGCATAYCCCC |
GGGGRTATGCGTCAY |
Transfac
Matys et al.(2006)
V$TAXCREB_02
|
0.894
|
0.867
|
Creb1
M00991_2.00 |
Mus musculus |
NNRTGACGYVN |
NBRCGTCAYNN |
PBM
Mann et al.(2013)
CREB1_M_HK
|
0.894
|
0.867
|
CREB1
M04265_2.00 |
Homo sapiens |
NRTGACRTCAYN |
NRTGAYGTCAYN |
SELEX
Yin et al.(2017)
CREB1_FL_Methyl-HT-SELEX
|
0.894
|
0.867
|
CREB1
M04261_2.00 |
Homo sapiens |
BRTGAYGYGND |
HNCRCRTCAYV |
SELEX
Yin et al.(2017)
CREB1_eDBD_Methyl-HT-SELEX_1
|
0.894
|
0.867
|
CREB1
M04262_2.00 |
Homo sapiens |
NRTGACRTCAYN |
NRTGAYGTCAYN |
SELEX
Yin et al.(2017)
CREB1_eDBD_Methyl-HT-SELEX_2
|
0.894
|
0.867
|
CREB1
M04263_2.00 |
Homo sapiens |
NRTGACGYV |
BRCGTCAYN |
SELEX
Yin et al.(2017)
CREB1_eDBD_Methyl-HT-SELEX_3
|
0.894
|
0.867
|
Crem
M01821_2.00 |
Mus musculus |
NRTKACGTMN |
NKACGTMAYN |
PBM
Weirauch et al.(2014)
pTH5002
|
0.880
|
0.850
|
Crem
M08845_2.00 |
Mus musculus |
SVVTGACGTSA |
TSACGTCABBS |
Misc
Kulakovskiy et al.(2013)
CREM_MOUSE.H11MO.0.C
|
0.880
|
0.850
|
CREM
M04229_2.00 |
Homo sapiens |
VVTBACGTVABN |
NVTBACGTVABB |
SELEX
Yin et al.(2017)
CREM_eDBD_HT-SELEX
|
0.849
|
0.750
|
CREM
M08784_2.00 |
Homo sapiens |
SVVTGACGTSA |
TSACGTCABBS |
Misc
Kulakovskiy et al.(2013)
CREM_HUMAN.H11MO.0.C
|
0.849
|
0.750
|
CREM
M09930_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$CREM_Q6_01
|
0.849
|
0.750
|
CREM
M09931_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$CREM_Q6
|
0.849
|
0.750
|
CREM
M04230_2.00 |
Homo sapiens |
NRTGACRTCAYN |
NRTGAYGTCAYN |
SELEX
Yin et al.(2017)
CREM_eDBD_Methyl-HT-SELEX
|
0.849
|
0.750
|
CrebB-17A
M03659_2.00 |
Drosophila melanogaster |
RTGACGTCAY |
RTGACGTCAY |
SELEX
Nitta et al.(2015)
CrebB-17A_1
|
0.817
|
0.800
|
CrebB-17A
M03660_2.00 |
Drosophila melanogaster |
RTGACGTCAY |
RTGACGTCAY |
SELEX
Nitta et al.(2015)
CrebB-17A_2
|
0.817
|
0.800
|
For this family, TFs with SR scores > 0.782 will likely have a similar motif |