ZNF35 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000169981 T095085_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables DNA-binding transcription factor activity and sequence-specific DNA binding activity. Predicted to be involved in cellular response to retinoic acid; regulation of transcription by RNA polymerase II; and spermatogenesis. Located in nucleus and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ZNF35
M08250_2.00		 Homo sapiens
TTVTARRARCTCTTTAYATAT
ATATRTAAAGAGYTYYTABAA		 ChIP-seq
Najafabadi et al.(2015b)
ZNF35		 (Direct) (Direct)
ZNF35
M08334_2.00		 Homo sapiens
BTTNTTKDYYHNHNDNDDCTYTTTDYWTNH
DNAWRHAAARAGHHNHNDNDRRHMAANAAV		 ChIP-seq
Schmitges et al.(2016)
P13682_1-10.RCADE		 (Direct) (Direct)
ZNF35
M10257_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ZNF35_04		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Zfp105
M00148_2.00 		Mus musculus
TTNTTKDNNN
NNNHMAANAA		 PBM
Badis et al.(2009)
Zfp105_2634 		0.813 0.960
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000379368 C2H2 ZF 222 244
ENSP00000379368 C2H2 ZF 250 272
ENSP00000379368 C2H2 ZF 278 300
ENSP00000379368 C2H2 ZF 306 328
ENSP00000379368 C2H2 ZF 334 356
ENSP00000379368 C2H2 ZF 362 384
ENSP00000379368 C2H2 ZF 390 412
ENSP00000379368 C2H2 ZF 418 440
ENSP00000379368 C2H2 ZF 446 468
ENSP00000379368 C2H2 ZF 474 496
ENSP00000379368 C2H2 ZF 502 524

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

33 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ZNF35 Gorilla gorilla ENSGGOG00000012968 I 0.827
ENSPPYG00000013957 Pongo abelii ENSPPYG00000013957 I 0.827
ENSNLEG00000005976 Nomascus leucogenys ENSNLEG00000005976 I 0.827
ZNF35 Pan troglodytes ENSPTRG00000014822 I 0.827
ZNF35 Microcebus murinus ENSMICG00000005568 I 0.826
ZNF35 Myotis lucifugus ENSMLUG00000011312 I 0.826
ZNF35 Equus caballus ENSECAG00000011523 I 0.826
ZNF35 Macaca mulatta ENSMMUG00000031705 I 0.826
ENSCSAG00000016604 Chlorocebus sabaeus ENSCSAG00000016604 I 0.826
ENSSTOG00000015127 Ictidomys tridecemlineatus ENSSTOG00000015127 I 0.825
ZNF35 Ochotona princeps ENSOPRG00000015405 I 0.825
ENSPANG00000011081 Papio anubis ENSPANG00000011081 I 0.825
ZNF35 Canis familiaris ENSCAFG00000030878 I 0.825
Myotis_brandtii_ZNF35_10014216 Myotis brandtii Myotis_brandtii_ZNF35_10014216 I 0.825
ENSAMEG00000004768 Ailuropoda melanoleuca ENSAMEG00000004768 I 0.825
ZNF35 Felis catus ENSFCAG00000010751 I 0.825
ZNF35 Tursiops truncatus ENSTTRG00000006741 I 0.824
ENSP00000379368 Macaca fascicularis ENSP00000379368 I 0.824
ENSOARG00000004597 Ovis aries ENSOARG00000004597 I 0.824
ZNF35 Dasypus novemcinctus ENSDNOG00000017898 I 0.824
ZNF35 Tupaia belangeri ENSTBEG00000007906 I 0.823
ZNF35 Echinops telfairi ENSETEG00000014012 I 0.823
ZNF35 Oryctolagus cuniculus ENSOCUG00000004757 I 0.823
ZNF35 Loxodonta africana ENSLAFG00000005378 I 0.823
ZNF35 Vicugna pacos ENSVPAG00000006933 I 0.822
ZNF35 Otolemur garnettii ENSOGAG00000014993 I 0.822
ZNF35 Pteropus vampyrus ENSPVAG00000013438 I 0.822
ZNF35 Cavia porcellus ENSCPOG00000010619 I 0.822
ZNF35 Bos taurus ENSBTAG00000034005 I 0.821
ZNF35 Callithrix jacchus ENSCJAG00000001827 I 0.819
Zfp105 Rattus norvegicus ENSRNOG00000032919 I 0.819
Zfp105 Dipodomys ordii ENSDORG00000007204 I 0.818
ZNF35 Choloepus hoffmanni ENSCHOG00000013987 I 0.806