ZNF25 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000175395 T095141_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ZNF25
M07643_2.00		 Homo sapiens
TTTCTAAATGSWKSRAYYTBTNTWHTTSW
WSAADWANAVARKTYSYWSCATTTAGAAA		 ChIP-seq+ChIP-exo
Barazandeh et al.(2018)
ZNF25.ChIP-seq.ReprocessedData		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000302222 C2H2 ZF 118 140
ENSP00000302222 C2H2 ZF 146 168
ENSP00000302222 C2H2 ZF 174 196
ENSP00000302222 C2H2 ZF 202 224
ENSP00000302222 C2H2 ZF 230 252
ENSP00000302222 C2H2 ZF 258 280
ENSP00000302222 C2H2 ZF 286 308
ENSP00000302222 C2H2 ZF 314 336
ENSP00000302222 C2H2 ZF 342 364
ENSP00000302222 C2H2 ZF 370 392
ENSP00000302222 C2H2 ZF 398 420
ENSP00000302222 C2H2 ZF 426 448

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

13 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ZNF25 Pan troglodytes ENSPTRG00000042406 I 0.821
ENSPPYG00000002203 Pongo abelii ENSPPYG00000002203 I 0.821
ENSNLEG00000008708 Nomascus leucogenys ENSNLEG00000008708 I 0.817
ENSPANG00000022735 Papio anubis ENSPANG00000022735 I 0.813
ENSMMUG00000001461 Macaca mulatta ENSMMUG00000001461 I 0.813
ZNF25 Callithrix jacchus ENSCJAG00000000783 I 0.807
ENSMMUP00000014495 Macaca fascicularis ENSMMUP00000014495 I 0.807
ZNF25 Otolemur garnettii ENSOGAG00000032242 I 0.797
ENSPANG00000018807 Papio anubis ENSPANG00000018807 I 0.794
ENSMMUG00000005404 Macaca mulatta ENSMMUG00000005404 I 0.789
Zfp9 Dipodomys ordii ENSDORG00000004502 I 0.761
ZNF25 Microcebus murinus ENSMICG00000004606 I 0.761
ZNF25 Choloepus hoffmanni ENSCHOG00000012000 I 0.755