ZFP3 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000180787 T095192_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ZFP3
M08258_2.00		 Homo sapiens
AACTCCTAYDCATCC
GGATGHRTAGGAGTT		 ChIP-seq
Najafabadi et al.(2015b)
ZFP3		 (Direct) (Direct)
ZFP3
M08355_2.00		 Homo sapiens
VHRARCTCCTAYNCANCC
GGNTGNRTAGGAGYTYDB		 ChIP-seq
Schmitges et al.(2016)
Q96NJ6_1-6.RCADE		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000320347 C2H2 ZF 141 163
ENSP00000320347 C2H2 ZF 169 191
ENSP00000320347 C2H2 ZF 197 219
ENSP00000320347 C2H2 ZF 225 247
ENSP00000320347 C2H2 ZF 253 275
ENSP00000320347 C2H2 ZF 281 303
ENSP00000320347 C2H2 ZF 309 331
ENSP00000320347 C2H2 ZF 337 359
ENSP00000320347 C2H2 ZF 365 387
ENSP00000320347 C2H2 ZF 393 415
ENSP00000320347 C2H2 ZF 421 443
ENSP00000320347 C2H2 ZF 449 471
ENSP00000320347 C2H2 ZF 477 499

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

29 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSPPYG00000007859 Pongo abelii ENSPPYG00000007859 I 0.827
ZFP3 Pan troglodytes ENSPTRG00000008622 I 0.827
ZFP3 Otolemur garnettii ENSOGAG00000027676 I 0.826
ENSOARG00000004280 Ovis aries ENSOARG00000004280 I 0.826
ZFP3 Procavia capensis ENSPCAG00000010125 I 0.826
ZFP3 Bos taurus ENSBTAG00000003699 I 0.826
ENSBTAP00000004817-D1 Bos grunniens ENSBTAP00000004817-D1 I 0.826
ENSTSYG00000004346 Tarsius syrichta ENSTSYG00000004346 I 0.826
ENSMICG00000008082 Microcebus murinus ENSMICG00000008082 I 0.825
ENSCPOG00000006167 Cavia porcellus ENSCPOG00000006167 I 0.825
ZFP3 Equus caballus ENSECAG00000002496 I 0.825
ZFP3 Dasypus novemcinctus ENSDNOG00000012978 I 0.825
ZFP3 Callithrix jacchus ENSCJAG00000011539 I 0.824
ZFP3 Pteropus vampyrus ENSPVAG00000000910 I 0.824
ZFP3 Gorilla gorilla ENSGGOG00000023389 I 0.824
ENSCSAG00000000570 Chlorocebus sabaeus ENSCSAG00000000570 I 0.823
ENSPANG00000012200 Papio anubis ENSPANG00000012200 I 0.823
ENSP00000320347 Macaca fascicularis ENSP00000320347 I 0.823
Zfp3 Dipodomys ordii ENSDORG00000013955 I 0.821
ENSMMUG00000004780 Macaca mulatta ENSMMUG00000004780 I 0.820
ENSSSCG00000025235 Sus scrofa ENSSSCG00000025235 I 0.820
Zfp3 Rattus norvegicus ENSRNOG00000005009 I 0.819
ENSSTOG00000021828 Ictidomys tridecemlineatus ENSSTOG00000021828 I 0.819
ZFP3 Loxodonta africana ENSLAFG00000002940 I 0.819
ZFP3 Myotis lucifugus ENSMLUG00000007598 I 0.817
Myotis_brandtii_ZFP3_10007485 Myotis brandtii Myotis_brandtii_ZFP3_10007485 I 0.817
ENSNLEG00000008964 Nomascus leucogenys ENSNLEG00000008964 I 0.809
ZFP3 Canis familiaris ENSCAFG00000028732 I 0.797
ENSAMEG00000019195 Ailuropoda melanoleuca ENSAMEG00000019195 I 0.760