CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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ZNF396
(
Homo sapiens
)
C2H2 ZF
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00096 (zf-C2H2)
IPR007087
ENSG00000186496
T095250_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Enables protein heterodimerization activity; protein homodimerization activity; and sequence-specific double-stranded DNA binding activity. Involved in negative regulation of transcription, DNA-templated. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
ZNF396
M04611_2.00
Homo sapiens
VTTTCGKACAB
VTGTMCGAAAB
SELEX
Yin et al.(2017)
ZNF396_FL_HT-SELEX
(Direct)
(Direct)
ZNF396
M04612_2.00
Homo sapiens
MTGTCCDAAAD
HTTTHGGACAK
SELEX
Yin et al.(2017)
ZNF396_FL_Methyl-HT-SELEX
(Direct)
(Direct)
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
For this family, TFs with SR scores >
0.755
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSP00000302310
C2H2 ZF
251
273
QKCDECGKIFSQSSALILHQRIH
ENSP00000302310
C2H2 ZF
279
301
YACDECAKAFSRSAILIQHRRTH
ENSP00000466500
C2H2 ZF
251
273
QKCDECGKIFSQSSALILHQRIH
ENSP00000466500
C2H2 ZF
279
301
YACDECAKAFSRSAILIQHRRTH
ENSP00000466500
C2H2 ZF
307
329
YKCHDCGKAFSQSSNLFRHRKRH
Links
Other
C2H2 ZF
family TFs
Other
Homo sapiens
TFs
6 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
ZNF396
Dasypus novemcinctus
ENSDNOG00000041114
I
0.823
ZNF396
Gorilla gorilla
ENSGGOG00000023692
I
0.813
ZNF396
Pan troglodytes
ENSPTRG00000009970
N
0.808
ZNF396
Microcebus murinus
ENSMICG00000017080
N
0.791
ZNF396
Tursiops truncatus
ENSTTRG00000006748
I
0.784
ZNF396
Sus scrofa
ENSSSCG00000030018
I
0.761