ZNF181 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000197841 T095358_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Zinc finger proteins have been shown to interact with nucleic acids and to have diverse functions. The zinc finger domain is a conserved amino acid sequence motif containing 2 specifically positioned cysteines and 2 histidines that are involved in coordinating zinc. Kruppel-related proteins form 1 family of zinc finger proteins. See MIM 604749 for additional information on zinc finger proteins.[supplied by OMIM, Jul 2003]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ZNF181
M07730_2.00		 Homo sapiens
VYYYSWGSTWSTNGGRMKGMKGHB
VDCMKCMKYCCNASWASCWSRRRB		 ChIP-seq+ChIP-exo
Barazandeh et al.(2018)
ZNF181.RCADE.ReprocessedData		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000376065 C2H2 ZF 281 303
ENSP00000376065 C2H2 ZF 309 331
ENSP00000376065 C2H2 ZF 337 359
ENSP00000376065 C2H2 ZF 365 387
ENSP00000376065 C2H2 ZF 393 415
ENSP00000376065 C2H2 ZF 421 443
ENSP00000376065 C2H2 ZF 449 471
ENSP00000376065 C2H2 ZF 477 499
ENSP00000376065 C2H2 ZF 505 527
ENSP00000376065 C2H2 ZF 533 555
ENSP00000376065 C2H2 ZF 561 583
ENSP00000419435 C2H2 ZF 236 258
ENSP00000419435 C2H2 ZF 264 286
ENSP00000419435 C2H2 ZF 292 314
ENSP00000419435 C2H2 ZF 320 342
ENSP00000419435 C2H2 ZF 348 370
ENSP00000419435 C2H2 ZF 376 398
ENSP00000419435 C2H2 ZF 404 426
ENSP00000419435 C2H2 ZF 432 454
ENSP00000419435 C2H2 ZF 460 482
ENSP00000419435 C2H2 ZF 488 510
ENSP00000419435 C2H2 ZF 516 538
ENSP00000420727 C2H2 ZF 237 259
ENSP00000420727 C2H2 ZF 265 287
ENSP00000420727 C2H2 ZF 293 315
ENSP00000420727 C2H2 ZF 321 343
ENSP00000420727 C2H2 ZF 349 371
ENSP00000420727 C2H2 ZF 377 399
ENSP00000420727 C2H2 ZF 405 427
ENSP00000420727 C2H2 ZF 433 455
ENSP00000420727 C2H2 ZF 461 483
ENSP00000420727 C2H2 ZF 489 511
ENSP00000420727 C2H2 ZF 517 539

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

23 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSNLEG00000010833 Nomascus leucogenys ENSNLEG00000010833 I 0.827
ZNF181 Gorilla gorilla ENSGGOG00000022196 I 0.827
ENSPPYG00000009841 Pongo abelii ENSPPYG00000009841 I 0.827
ZNF181 Pan troglodytes ENSPTRG00000024231 I 0.826
ENSPANG00000004606 Papio anubis ENSPANG00000004606 I 0.822
ENSMMUG00000005889 Macaca mulatta ENSMMUG00000005889 I 0.822
ENSVPAG00000012286 Vicugna pacos ENSVPAG00000012286 I 0.816
ENSCSAG00000004595 Chlorocebus sabaeus ENSCSAG00000004595 I 0.816
ENSCAFG00000031202 Canis familiaris ENSCAFG00000031202 I 0.814
ENSOARG00000004622 Ovis aries ENSOARG00000004622 I 0.814
ENSP00000376065-D1 Bos grunniens ENSP00000376065-D1 I 0.814
Myotis_brandtii_ZNF181_10035187 Myotis brandtii Myotis_brandtii_ZNF181_10035187 I 0.813
ENSBTAG00000009889 Bos taurus ENSBTAG00000009889 I 0.813
ENSFCAG00000024861 Felis catus ENSFCAG00000024861 I 0.812
ENSOGAG00000017120 Otolemur garnettii ENSOGAG00000017120 I 0.810
ENSMPUG00000007424 Mustela putorius furo ENSMPUG00000007424 I 0.808
ENSSTOG00000003480 Ictidomys tridecemlineatus ENSSTOG00000003480 I 0.806
ENSSSCG00000002877 Sus scrofa ENSSSCG00000002877 I 0.799
ENSTTRG00000002923 Tursiops truncatus ENSTTRG00000002923 I 0.792
ENSECAG00000011139 Equus caballus ENSECAG00000011139 I 0.789
ENSMMUP00000020673 Macaca fascicularis ENSMMUP00000020673 I 0.773
ENSOPRG00000003671 Ochotona princeps ENSOPRG00000003671 I 0.770