ZNF10 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000256223 T095475_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
The protein encoded by this gene contains a C2H2 zinc finger, and has been shown to function as a transcriptional repressor. The Kruppel-associated box (KRAB) domain of this protein is found to be responsible for its transcriptional repression activity. RING finger containing protein TIF1 was reported to interact with the KRAB domain, and may serve as a mediator for the repression activity of this protein. [provided by RefSeq, Jul 2008]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ZNF10
M07774_2.00		 Homo sapiens
CCCTACCTC
GAGGTAGGG		 ChIP-seq+ChIP-exo
Barazandeh et al.(2018)
ZNF10.RCADE.OriginalMapping		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000248211 C2H2 ZF 265 287
ENSP00000248211 C2H2 ZF 293 315
ENSP00000248211 C2H2 ZF 321 343
ENSP00000248211 C2H2 ZF 349 371
ENSP00000248211 C2H2 ZF 377 399
ENSP00000248211 C2H2 ZF 405 427
ENSP00000248211 C2H2 ZF 433 455
ENSP00000248211 C2H2 ZF 461 483
ENSP00000248211 C2H2 ZF 489 511
ENSP00000248211 C2H2 ZF 517 539
ENSP00000384893 C2H2 ZF 159 181
ENSP00000384893 C2H2 ZF 187 209
ENSP00000384893 C2H2 ZF 215 237
ENSP00000384893 C2H2 ZF 243 265
ENSP00000384893 C2H2 ZF 271 293
ENSP00000384893 C2H2 ZF 299 321
ENSP00000384893 C2H2 ZF 327 349
ENSP00000384893 C2H2 ZF 355 377
ENSP00000384893 C2H2 ZF 383 405
ENSP00000393814 C2H2 ZF 265 287
ENSP00000393814 C2H2 ZF 293 315
ENSP00000393814 C2H2 ZF 321 343
ENSP00000393814 C2H2 ZF 349 371
ENSP00000393814 C2H2 ZF 377 399
ENSP00000393814 C2H2 ZF 405 427
ENSP00000393814 C2H2 ZF 433 455
ENSP00000393814 C2H2 ZF 461 483
ENSP00000393814 C2H2 ZF 489 511
ENSP00000393814 C2H2 ZF 517 539

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

18 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ZNF268 Macaca mulatta ENSMMUG00000009789 I 0.827
ENSPANG00000019207 Papio anubis ENSPANG00000019207 I 0.827
ENSPPYG00000005155 Pongo abelii ENSPPYG00000005155 I 0.827
ENSMMUP00000012813 Macaca fascicularis ENSMMUP00000012813 I 0.827
ENSMPUG00000002717 Mustela putorius furo ENSMPUG00000002717 I 0.819
ZNF10 Felis catus ENSFCAG00000003016 I 0.818
ZNF10 Canis familiaris ENSCAFG00000031976 I 0.817
ZNF10 Callithrix jacchus ENSCJAG00000034524 I 0.815
ZNF10 Pteropus vampyrus ENSPVAG00000014539 I 0.815
ENSOARG00000008678 Ovis aries ENSOARG00000008678 I 0.813
ZNF10 Bos taurus ENSBTAG00000039242 I 0.813
ZNF10 Tupaia belangeri ENSTBEG00000015869 I 0.808
ZNF10 Choloepus hoffmanni ENSCHOG00000002413 I 0.801
ENSSSCG00000022601 Sus scrofa ENSSSCG00000022601 I 0.798
ENSTSYG00000010130 Tarsius syrichta ENSTSYG00000010130 I 0.798
ZNF10 Dasypus novemcinctus ENSDNOG00000013886 I 0.795
ZNF10 Tursiops truncatus ENSTTRG00000004371 I 0.790