CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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ZIM2
(
Homo sapiens
)
C2H2 ZF
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00096 (zf-C2H2)
IPR007087
ENSG00000269699
T095496_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
In human, ZIM2 and PEG3 (GeneID:5178) are two distinct genes that share a set of 5' exons and have a common promoter, and both genes are paternally expressed. Alternative splicing events connect the shared exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. This is in contrast to mouse and cow, where ZIM2 and PEG3 genes do not share exons in common, and the imprinting status of ZIM2 is also not conserved amongst mammals. Additional 5' alternatively spliced transcripts encoding the same protein have been found for the human ZIM2 gene. [provided by RefSeq, Oct 2010]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
ZIM2
M07779_2.00
Homo sapiens
YCNBSYBSCYTYYYCHBCCVGCCYGKGGYY
RRCCMCRGGCBGGVDGRRRARGSVRSVNGR
ChIP-seq+ChIP-exo
Barazandeh et al.(2018)
ZIM2.ChIP-seq.ReprocessedData
(Direct)
(Direct)
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
For this family, TFs with SR scores >
0.755
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSP00000468984
C2H2 ZF
329
350
RCEFCKRTFSTQVALRRHERIH
ENSP00000468984
C2H2 ZF
356
378
YECKQCAEAFYLMPHLNRHQKTH
ENSP00000468984
C2H2 ZF
412
434
FECFQCGKAFLQNVHLLQHLKAH
ENSP00000468984
C2H2 ZF
466
488
CQCCDCGRVFSRNSYLIQHYRTH
ENSP00000468984
C2H2 ZF
494
516
YQCQLCGKCFGRPSYLTQHYQLH
ENSP00000470326
C2H2 ZF
329
350
RCEFCKRTFSTQVALRRHERIH
ENSP00000470326
C2H2 ZF
356
378
YECKQCAEAFYLMPHLNRHQKTH
ENSP00000470326
C2H2 ZF
412
434
FECFQCGKAFLQNVHLLQHLKAH
ENSP00000470326
C2H2 ZF
466
488
CQCCDCGRVFSRNSYLIQHYRTH
ENSP00000470326
C2H2 ZF
494
516
YQCQLCGKCFGRPSYLTQHYQLH
ENSP00000472306
C2H2 ZF
329
350
RCEFCKRTFSTQVALRRHERIH
ENSP00000472306
C2H2 ZF
356
378
YECKQCAEAFYLMPHLNRHQKTH
ENSP00000472306
C2H2 ZF
412
434
FECFQCGKAFLQNVHLLQHLKAH
ENSP00000472306
C2H2 ZF
466
488
CQCCDCGRVFSRNSYLIQHYRTH
ENSP00000472306
C2H2 ZF
494
516
YQCQLCGKCFGRPSYLTQHYQLH
ENSP00000486502
C2H2 ZF
329
350
RCEFCKRTFSTQVALRRHERIH
ENSP00000486502
C2H2 ZF
356
378
YECKQCAEAFYLMPHLNRHQKTH
ENSP00000486502
C2H2 ZF
412
434
FECFQCGKAFLQNVHLLQHLKAH
ENSP00000486502
C2H2 ZF
466
488
CQCCDCGRVFSRNSYLIQHYRTH
ENSP00000486502
C2H2 ZF
494
516
YQCQLCGKCFGRPSYLTQHYQLH
Links
Other
C2H2 ZF
family TFs
Other
Homo sapiens
TFs
3 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
PEG3
Macaca mulatta
ENSMMUG00000017852
I
0.768
ENSCSAG00000001663
Chlorocebus sabaeus
ENSCSAG00000001663
I
0.768