Zkscan1 (Mus musculus)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSMUSG00000029729 T101087_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in early conceptus; genitourinary system; nervous system; and olfactory epithelium. Orthologous to human ZKSCAN1 (zinc finger with KRAB and SCAN domains 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Zkscan1
M00771_2.00		 Mus musculus
NNNHDHDNNN
NNNHDHDNNN		 PBM
Weirauch et al.(2013)
pTH2280		 (Direct) (Direct)
Zkscan1
M08985_2.00		 Mus musculus
DVHDBNCCTACTRTGTGCH
DGCACAYAGTAGGNVHDBH		 Misc
Kulakovskiy et al.(2013)
ZKSC1_MOUSE.H11MO.0.A		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ZKSCAN1
M05847_2.00 		Homo sapiens
NNNCCTACTAHGH
DCDTAGTAGGNNN		 SMiLE-seq
Isakova et al.(2017)
ZKSCAN1 		0.825 0.993
ZKSCAN1
M08874_2.00 		Homo sapiens
DVHDBNCCTACTRTGTGCH
DGCACAYAGTAGGNVHDBH		 Misc
Kulakovskiy et al.(2013)
ZKSC1_HUMAN.H11MO.0.B 		0.825 0.993
For this family, TFs with SR scores > 0.755 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00771_2.00 C2H2 ZF 16 38
M00771_2.00 C2H2 ZF 44 66
M00771_2.00 C2H2 ZF 72 94
M00771_2.00 C2H2 ZF 100 122
M00771_2.00 C2H2 ZF 128 150
M00771_2.00 C2H2 ZF 156 178

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000019660 C2H2 ZF 375 397
ENSMUSP00000019660 C2H2 ZF 403 425
ENSMUSP00000019660 C2H2 ZF 431 453
ENSMUSP00000019660 C2H2 ZF 459 481
ENSMUSP00000019660 C2H2 ZF 487 509
ENSMUSP00000019660 C2H2 ZF 515 537
ENSMUSP00000068480 C2H2 ZF 302 324
ENSMUSP00000068480 C2H2 ZF 330 352
ENSMUSP00000068480 C2H2 ZF 358 380
ENSMUSP00000068480 C2H2 ZF 386 408
ENSMUSP00000068480 C2H2 ZF 414 436
ENSMUSP00000068480 C2H2 ZF 442 464
ENSMUSP00000106587 C2H2 ZF 302 324
ENSMUSP00000106587 C2H2 ZF 330 352
ENSMUSP00000106587 C2H2 ZF 358 380
ENSMUSP00000106587 C2H2 ZF 386 408
ENSMUSP00000106587 C2H2 ZF 414 436
ENSMUSP00000106587 C2H2 ZF 442 464
ENSMUSP00000106588 C2H2 ZF 302 324
ENSMUSP00000106588 C2H2 ZF 330 352
ENSMUSP00000106588 C2H2 ZF 358 380
ENSMUSP00000106588 C2H2 ZF 386 408
ENSMUSP00000106588 C2H2 ZF 414 436
ENSMUSP00000106588 C2H2 ZF 442 464

Links

Other C2H2 ZF family TFs
Other Mus musculus TFs

41 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ZKSCAN1 Loxodonta africana ENSLAFG00000015561 I 0.827
ZKSCAN1 Procavia capensis ENSPCAG00000005258 I 0.827
Zkscan1 Rattus norvegicus ENSRNOG00000001335 I 0.827
ZKSCAN1 Cavia porcellus ENSCPOG00000005770 I 0.827
ZKSCAN1 Canis familiaris ENSCAFG00000031298 I 0.825
ENSPPYG00000017394 Pongo abelii ENSPPYG00000017394 I 0.825
ZKSCAN1 Pan troglodytes ENSPTRG00000019468 I 0.825
ENSPANG00000021727 Papio anubis ENSPANG00000021727 I 0.825
ENSOPRG00000005191 Ochotona princeps ENSOPRG00000005191 I 0.825
ZKSCAN1 Oryctolagus cuniculus ENSOCUG00000015333 I 0.825
ZKSCAN1 Otolemur garnettii ENSOGAG00000016308 I 0.825
ZKSCAN1 Bos taurus ENSBTAG00000016757 I 0.825
ENSSSCG00000007643 Sus scrofa ENSSSCG00000007643 I 0.825
ZKSCAN1 Vicugna pacos ENSVPAG00000008160 I 0.825
ENSP00000323148 Macaca fascicularis ENSP00000323148 I 0.825
Myotis_brandtii_ZKSCAN1_10002829 Myotis brandtii Myotis_brandtii_ZKSCAN1_10002829 I 0.825
ZKSCAN1 Tursiops truncatus ENSTTRG00000012308 I 0.825
ENSTSYG00000002021 Tarsius syrichta ENSTSYG00000002021 I 0.825
ENSSTOG00000010173 Ictidomys tridecemlineatus ENSSTOG00000010173 I 0.825
ZKSCAN1 Tupaia belangeri ENSTBEG00000013785 I 0.825
ENSCJAG00000015664 Callithrix jacchus ENSCJAG00000015664 I 0.825
ENSOARG00000017971 Ovis aries ENSOARG00000017971 I 0.825
ZKSCAN1 Equus caballus ENSECAG00000022801 I 0.825
ENSNLEG00000011334 Nomascus leucogenys ENSNLEG00000011334 I 0.825
ZKSCAN1 Gorilla gorilla ENSGGOG00000005107 I 0.825
ZKSCAN1 Homo sapiens ENSG00000106261 D 0.825
ZKSCAN1 Felis catus ENSFCAG00000003558 I 0.825
ZKSCAN1 Choloepus hoffmanni ENSCHOG00000008882 I 0.825
ZKSCAN1 Erinaceus europaeus ENSEEUG00000006215 I 0.825
ENSMPUG00000010898 Mustela putorius furo ENSMPUG00000010898 I 0.825
ENSAMEG00000011243 Ailuropoda melanoleuca ENSAMEG00000011243 I 0.825
ENSCSAG00000017829 Chlorocebus sabaeus ENSCSAG00000017829 I 0.825
ZKSCAN1 Macaca mulatta ENSMMUG00000008601 I 0.825
ZKSCAN1 Microcebus murinus ENSMICG00000003957 I 0.825
ZKSCAN1 Echinops telfairi ENSETEG00000002676 I 0.824
ENSDORG00000015914 Dipodomys ordii ENSDORG00000015914 I 0.824
ZKSCAN1 Sorex araneus ENSSARG00000002353 I 0.814
ZKSCAN1 Monodelphis domestica ENSMODG00000004145 I 0.809
ENSMEUG00000006695 Macropus eugenii ENSMEUG00000006695 I 0.809
ENSSHAG00000012439 Sarcophilus harrisii ENSSHAG00000012439 I 0.809