Zfp335 (Rattus norvegicus)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSRNOG00000017290 T109049_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor coactivator activity. Predicted to be involved in several processes, including histone H3-K4 trimethylation; nervous system development; and regulation of gene expression. Predicted to act upstream of or within in utero embryonic development and nervous system development. Predicted to be located in nucleoplasm. Predicted to be part of histone methyltransferase complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 10. Orthologous to human ZNF335 (zinc finger protein 335). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Zfp335
M08998_2.00 		Mus musculus
RGSTGYCYNNNSHDNTGCCTGH
DCAGGCANHDSNNNRGRCASCY		 Misc
Kulakovskiy et al.(2013)
ZN335_MOUSE.H11MO.0.A 		0.822 0.996
ZNF335
M08952_2.00 		Homo sapiens
RGSTGYCYNNNSHDNTGCCTGH
DCAGGCANHDSNNNRGRCASCY		 Misc
Kulakovskiy et al.(2013)
ZN335_HUMAN.H11MO.0.A 		0.819 0.974
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSRNOP00000023523 C2H2 ZF 496 518
ENSRNOP00000023523 C2H2 ZF 524 546
ENSRNOP00000023523 C2H2 ZF 563 585
ENSRNOP00000023523 C2H2 ZF 591 613
ENSRNOP00000023523 C2H2 ZF 622 644
ENSRNOP00000023523 C2H2 ZF 679 702
ENSRNOP00000023523 C2H2 ZF 1019 1041
ENSRNOP00000023523 C2H2 ZF 1047 1069
ENSRNOP00000023523 C2H2 ZF 1075 1097
ENSRNOP00000023523 C2H2 ZF 1103 1126

Links

Other C2H2 ZF family TFs
Other Rattus norvegicus TFs

23 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ZNF335 Cavia porcellus ENSCPOG00000000138 I 0.823
ZNF335 Pteropus vampyrus ENSPVAG00000000383 I 0.823
ENSSTOG00000006323 Ictidomys tridecemlineatus ENSSTOG00000006323 I 0.823
Zfp335 Dipodomys ordii ENSDORG00000007083 I 0.823
Zfp335 Mus musculus ENSMUSG00000039834 D 0.822
Myotis_brandtii_ZNF335_10013703 Myotis brandtii Myotis_brandtii_ZNF335_10013703 I 0.821
ZNF335 Myotis lucifugus ENSMLUG00000000282 I 0.821
ZNF335 Tursiops truncatus ENSTTRG00000012103 I 0.820
ZNF335 Otolemur garnettii ENSOGAG00000015292 I 0.819
ENSPPYG00000011082 Pongo abelii ENSPPYG00000011082 I 0.819
ZNF335 Callithrix jacchus ENSCJAG00000017215 I 0.819
ZNF335 Equus caballus ENSECAG00000023647 I 0.819
ZNF335 Pan troglodytes ENSPTRG00000023353 I 0.819
ZNF335 Oryctolagus cuniculus ENSOCUG00000016059 I 0.819
ENSCSAG00000014693 Chlorocebus sabaeus ENSCSAG00000014693 I 0.819
ZNF335 Homo sapiens ENSG00000198026 D 0.819
ZNF335 Loxodonta africana ENSLAFG00000016142 I 0.819
ZNF335 Gorilla gorilla ENSGGOG00000013550 I 0.819
ZNF335 Bos taurus ENSBTAG00000010130 I 0.812
ENSBTAP00000053387-D1 Bos grunniens ENSBTAP00000053387-D1 I 0.812
ENSMPUG00000017610 Mustela putorius furo ENSMPUG00000017610 I 0.810
ZNF335 Canis familiaris ENSCAFG00000009882 I 0.810
ENSAMEG00000012733 Ailuropoda melanoleuca ENSAMEG00000012733 I 0.810