DMRTA1 (Homo sapiens)
DM

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00751 (DM) IPR001275 ENSG00000176399 T169052_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in germ cell development; regulation of transcription by RNA polymerase II; and sex differentiation. Predicted to act upstream of or within male mating behavior and ovarian follicle development. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
DMRTA1
M04694_2.00		 Homo sapiens
NWTGTADCAWHH
DDWTGHTACAWN		 SELEX
Yin et al.(2017)
DMRTA1_FL_HT-SELEX		 (Direct) (Direct)
DMRTA1
M04695_2.00		 Homo sapiens
RWTGTADCRDHH
DDHYGHTACAWY		 SELEX
Yin et al.(2017)
DMRTA1_FL_Methyl-HT-SELEX		 (Direct) (Direct)
DMRTA1
M10435_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$DMRT4_01		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.845 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000319651 DM 93 139
ENSP00000319651 DM 225 247

Links

Other DM family TFs
Other Homo sapiens TFs

5 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
DMRTA1 Pan troglodytes ENSPTRG00000020829 I 0.872
ENSPPYG00000019167 Pongo abelii ENSPPYG00000019167 I 0.872
ENSNLEG00000016399 Nomascus leucogenys ENSNLEG00000016399 I 0.872
ENSMMUG00000002551 Macaca mulatta ENSMMUG00000002551 I 0.872
DMRTA1 Gorilla gorilla ENSGGOG00000009094 I 0.872