fkh-10 (Caenorhabditis elegans)
Forkhead

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00250 (Forkhead) IPR001766 WBGene00001442 T188808_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anatomical structure morphogenesis; cell differentiation; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in gonad; head ganglion; head neurons; and pharyngeal neurons. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 43. Orthologous to human FOXJ1 (forkhead box J1) and FOXK2 (forkhead box K2). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
fd102C
M03750_2.00 		Drosophila melanogaster
SCGAAGRACSKCAAGN
NCTTGMSGTYCTTCGS		 SELEX
Nitta et al.(2015)
fd102C_1 		0.723 0.750
fd102C
M03751_2.00 		Drosophila melanogaster
CGAAGRACSK
MSGTYCTTCG		 SELEX
Nitta et al.(2015)
fd102C_2 		0.723 0.750
For this family, TFs with SR scores > 0.664 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
C25A1.2.1 Forkhead 42 129
C25A1.2.2 Forkhead 42 129

Links

Other Forkhead family TFs
Other Caenorhabditis elegans TFs

128 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CBG12232 Caenorhabditis briggsae CBG12232 I 0.837
DICVIV_08747 Dictyocaulus viviparus DICVIV_08747 I 0.806
CGOC_0000329701 Cylicostephanus goldi CGOC_0000329701 I 0.806
ANCCAN_30535 Ancylostoma caninum ANCCAN_30535 I 0.806
ACAC_0000772401 Angiostrongylus cantonensis ACAC_0000772401 I 0.806
ANCCEY_07256 Ancylostoma ceylanicum ANCCEY_07256 I 0.806
ACOC_0000013301 Angiostrongylus costaricensis ACOC_0000013301 I 0.806
OESDEN_02306 Oesophagostomum dentatum OESDEN_02306 I 0.806
NBR_0000095001 Nippostrongylus brasiliensis NBR_0000095001 I 0.806
NECAME_04384 Necator americanus NECAME_04384 I 0.806
SVUK_0000095001 Strongylus vulgaris SVUK_0000095001 I 0.806
L889_g23699 Steinernema feltiae L889_g23699 I 0.800
L898_g16488 Steinernema monticolum L898_g16488 I 0.800
L893_g32272 Steinernema glaseri L893_g32272 I 0.799
CRE23967 Caenorhabditis remanei CRE23967 I 0.799
CBN31271 Caenorhabditis brenneri CBN31271 I 0.798
RPRC002475 Rhodnius prolixus RPRC002475 I 0.793
PHUM244390 Pediculus humanus PHUM244390 I 0.793
HCOI02176800 Haemonchus contortus HCOI02176800 I 0.790
HPBE_0001940301 Heligmosomoides bakeri HPBE_0001940301 I 0.790
HPLM_0001940801 Haemonchus placei HPLM_0001940801 I 0.790
PPAI000826 Phlebotomus papatasi PPAI000826 I 0.785
LLOJ007413 Lutzomyia longipalpis LLOJ007413 I 0.785
BGIBMGA001488 Bombyx mori BGIBMGA001488 I 0.785
AFAF018179 Anopheles farauti AFAF018179 I 0.784
ACHR005020 Anopheles christyi ACHR005020 I 0.784
AEPI005796 Anopheles epiroticus AEPI005796 I 0.784
AATE003062 Anopheles atroparvus AATE003062 I 0.784
ADIR000975 Anopheles dirus ADIR000975 I 0.784
ACUA020854 Anopheles culicifacies ACUA020854 I 0.784
AALB006646 Anopheles albimanus AALB006646 I 0.784
CpipJ_CPIJ009525 Culex pipiens CpipJ_CPIJ009525 I 0.784
TC004761 Tribolium castaneum TC004761 I 0.784
LDEC001528 Leptinotarsa decemlineata LDEC001528 I 0.784
AFUN011568 Anopheles funestus AFUN011568 I 0.784
AARA001108 Anopheles arabiensis AARA001108 I 0.784
ASTEI06209 Anopheles stephensi ASTEI06209 I 0.784
AGAP000069 Anopheles gambiae AGAP000069 I 0.784
HMEL012130 Heliconius melpomene HMEL012130 I 0.784
L596_g8980 Steinernema carpocapsae L596_g8980 I 0.784
CPIJ009525 Culex quinquefasciatus CPIJ009525 I 0.784
L892_g5229 Steinernema scapterisci L892_g5229 I 0.784
ASIS005525 Anopheles sinensis ASIS005525 I 0.784
AAEL000236 Aedes aegypti AAEL000236 I 0.784
AQUA008315 Anopheles quadriannulatus AQUA008315 I 0.784
AMEM007373 Anopheles merus AMEM007373 I 0.784
AMEC012184 Anopheles melas AMEC012184 I 0.784
AMAM011474 Anopheles maculatus AMAM011474 I 0.784
AMIN002134 Anopheles minimus AMIN002134 I 0.784
YQE_09099 Dendroctonus ponderosae YQE_09099 I 0.780
CLEC001579 Cimex lectularius CLEC001579 I 0.777
DME_0000296101 Dracunculus medinensis DME_0000296101 I 0.776
D917_06283 Trichinella nativa D917_06283 I 0.775
Ocbimv22038677m.g Octopus bimaculoides Ocbimv22038677m.g I 0.775
DAPPUDRAFT_50302 Daphnia pulex DAPPUDRAFT_50302 I 0.774
SBAD_0000682701 Soboliphyme baturini SBAD_0000682701 I 0.773
BGLB003447 Biomphalaria glabrata BGLB003447 I 0.771
KGM_06490 Danaus plexippus KGM_06490 I 0.768
nOo.2.0.1.g07936 Onchocerca ochengi nOo.2.0.1.g07936 I 0.767
BTMF_0001614201 Brugia timori BTMF_0001614201 I 0.767
WBGene00238063 Onchocerca volvulus WBGene00238063 I 0.767
ACEP16720 Atta cephalotes ACEP16720 I 0.765
SINV17382 Solenopsis invicta SINV17382 I 0.765
GB50374 Apis mellifera GB50374 I 0.765
NV18839 Nasonia vitripennis NV18839 I 0.765
Hsal_00505--XP_001121752.1_APIME Harpegnathos saltator Hsal_00505--XP_001121752.1_APIME I 0.765
Cflo_07366--XP_001121752.1_APIME Camponotus floridanus Cflo_07366--XP_001121752.1_APIME I 0.765
NEMVEDRAFT_v1g39596 Nematostella vectensis NEMVEDRAFT_v1g39596 I 0.763
HelroG84905 Helobdella robusta HelroG84905 I 0.761
TCLT_0000158601 Thelazia callipaeda TCLT_0000158601 I 0.761
ACYPI002885 Acyrthosiphon pisum ACYPI002885 I 0.760
ASU_00906 Ascaris suum ASU_00906 I 0.759
TCNE_0000717001 Toxocara canis TCNE_0000717001 I 0.759
nDi.2.2.2.g05283 Dirofilaria immitis nDi.2.2.2.g05283 I 0.756
ISCW003951 Ixodes scapularis ISCW003951 I 0.756
EEL_0000313101 Elaeophora elaphi EEL_0000313101 I 0.755
D918_04073 Trichuris suis D918_04073 I 0.754
TMUE_s0045003300 Trichuris muris TMUE_s0045003300 I 0.754
TTRE_0000002201 Trichuris trichiura TTRE_0000002201 I 0.754
BXY_1193200 Bursaphelenchus xylophilus BXY_1193200 I 0.753
GPUH_0002128801 Gongylonema pulchrum GPUH_0002128801 I 0.752
WUBG_10187 Wuchereria bancrofti WUBG_10187 I 0.746
SMU15004452 Schmidtea mediterranea SMU15004452 I 0.745
GK13662 Drosophila willistoni FBgn0215670 I 0.742
Sakowv30023329m.g Saccoglossus kowalevskii Sakowv30023329m.g I 0.742
TTAC_0000212301 Hydatigera taeniaeformis TTAC_0000212301 I 0.740
ECANG7_08418 Echinococcus canadensis ECANG7_08418 I 0.740
GA10799 Drosophila pseudoobscura FBgn0070855 I 0.739
GF10343 Drosophila ananassae FBgn0087384 I 0.739
LCUP005975 Lucilia cuprina LCUP005975 I 0.739
GJ15974 Drosophila virilis FBgn0203160 I 0.739
tetur01g09690 Tetranychus urticae tetur01g09690 I 0.739
GL15611 Drosophila persimilis FBgn0153215 I 0.739
GI14084 Drosophila mojavensis FBgn0136838 I 0.739
GH24005 Drosophila grimshawi FBgn0131461 I 0.739
SMAR012448 Strigamia maritima SMAR012448 I 0.738
CGI_10003726 Crassostrea gigas CGI_10003726 I 0.738
CapteG111555 Capitella teleta CapteG111555 I 0.736
e_gw.6.414.1 Branchiostoma floridae e_gw.6.414.1 I 0.733
D915_07563 Fasciola hepatica D915_07563 I 0.732
HelroG146879 Helobdella robusta HelroG146879 I 0.729
CJA06474 Caenorhabditis japonica CJA06474 N 0.726
HmN_000125600 Hymenolepis microstoma HmN_000125600 I 0.724
HDID_0000955901 Hymenolepis diminuta HDID_0000955901 I 0.724
HNAJ_0000218001 Hymenolepis nana HNAJ_0000218001 I 0.724
LotgiG79781 Lottia gigantea LotgiG79781 I 0.724
GE14501 Drosophila yakuba FBgn0232105 I 0.723
GM26767 Drosophila sechellia FBgn0181620 I 0.723
fd102C Drosophila melanogaster FBgn0039937 D 0.723
GG16435 Drosophila erecta FBgn0108666 I 0.723
MESCA005623 Megaselia scalaris MESCA005623 I 0.718
NEMVEDRAFT_v1g59063 Nematostella vectensis NEMVEDRAFT_v1g59063 I 0.716
Alligator_sinensis_CCG003246.1 Alligator sinensis Alligator_sinensis_CCG003246.1 N 0.716
Pvit_09831 Pogona vitticeps Pvit_09831 N 0.716
Ogr12164 Ophisaurus gracilis Ogr12164 N 0.716
ENSLACG00000010819 Latimeria chalumnae ENSLACG00000010819 N 0.716
ENSONIG00000004794 Oreochromis niloticus ENSONIG00000004794 N 0.703
XP_002159677.1 Hydra magnipapillata XP_002159677.1 I 0.701
NEMVEDRAFT_v1g125256 Nematostella vectensis NEMVEDRAFT_v1g125256 I 0.687
CapteG82802 Capitella teleta CapteG82802 I 0.685
Cmyd_10015602 Chelonia mydas Cmyd_10015602 N 0.683
ENSPFOG00000001440 Poecilia formosa ENSPFOG00000001440 N 0.678
foxq2 Oryzias latipes ENSORLG00000004973 N 0.678
ENSXMAG00000012768 Xiphophorus maculatus ENSXMAG00000012768 N 0.678
foxq2 Danio rerio ENSDARG00000071394 N 0.678
Ocbimv22016417m.g Octopus bimaculoides Ocbimv22016417m.g N 0.672
CapteG148596 Capitella teleta CapteG148596 N 0.664