ENSCING00000007395 (Ciona intestinalis)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSCING00000007395 T207843_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ENSCING00000007395
M02076_2.00		 Ciona intestinalis
NNNDWNWR
YWNWHNNN		 PBM
Weirauch et al.(2014)
pTH5922		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
bap
M00560_2.00 		Drosophila melanogaster
NDAAGTRBNN
NNVYACTTHN		 PBM
Busser et al.(2012a)
Bap 		0.829 0.719
bap
M02119_2.00 		Drosophila melanogaster
NYTAAGTRSNN
NNSYACTTARN		 PBM
Weirauch et al.(2014)
pTH5945 		0.829 0.719
bap
M03812_2.00 		Drosophila melanogaster
NNTAAGTGBN
NVCACTTANN		 SELEX
Nitta et al.(2015)
bap_1 		0.829 0.719
bap
M06504_2.00 		Drosophila melanogaster
TTAAGTR
YACTTAA		 B1H
Mathelier et al.(2014)
MA0211.1 		0.829 0.719
bap
M06287_2.00 		Drosophila melanogaster
NBTTAAGTRN
NYACTTAAVN		 B1H
Zhu et al.(2011)
Bap_Cell_FBgn0004862 		0.829 0.719
bap
M06288_2.00 		Drosophila melanogaster
NYTAAKTR
YAMTTARN		 B1H
Zhu et al.(2011)
Bap_SOLEXA_FBgn0004862 		0.829 0.719
Nkx3-2
M00506_2.00 		Mus musculus
NNRAGDRNN
NNYHCTYNN		 PBM
Berger et al.(2008)
Bapx1_2343 		0.825 0.684
NKX3-2
M05012_2.00 		Homo sapiens
NNTAAGTGSN
NSCACTTANN		 SELEX
Yin et al.(2017)
NKX3-2_eDBD_HT-SELEX 		0.825 0.684
NKX3-2
M09138_2.00 		Homo sapiens
TTAAGTGBNH
DNVCACTTAA		 Misc
Kulakovskiy et al.(2013)
NKX32_HUMAN.H11MO.0.C 		0.825 0.684
Nkx3-2
M09212_2.00 		Mus musculus
TTAAGTGBNH
DNVCACTTAA		 Misc
Kulakovskiy et al.(2013)
NKX32_MOUSE.H11MO.0.B 		0.825 0.684
NKX3-2
M10663_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NKX32_01 		0.825 0.684
NKX3-2
M05013_2.00 		Homo sapiens
NNTAAGTGBN
NVCACTTANN		 SELEX
Yin et al.(2017)
NKX3-2_eDBD_Methyl-HT-SELEX_1 		0.825 0.684
NKX3-2
M05014_2.00 		Homo sapiens
NTAACGHB
VDCGTTAN		 SELEX
Yin et al.(2017)
NKX3-2_eDBD_Methyl-HT-SELEX_2 		0.825 0.684
Nkx3-1
M00170_2.00 		Mus musculus
NDAAGTRBNN
NNVYACTTHN		 PBM
Badis et al.(2009)
Nkx3-1_2923 		0.820 0.649
Nkx3-1
M00420_2.00 		Mus musculus
NNAAGTRBNN
NNVYACTTNN		 PBM
Berger et al.(2008)
Nkx3-1_2923 		0.820 0.649
NKX3-1
M05255_2.00 		Homo sapiens
NNTAAGTGSN
NSCACTTANN		 SELEX
Yin et al.(2017)
NKX3-1_eDBD_HT-SELEX 		0.820 0.649
NKX3-1
M09154_2.00 		Homo sapiens
NYDAAGTGBYWD
HWRVCACTTHRN		 Misc
Kulakovskiy et al.(2013)
NKX31_HUMAN.H11MO.0.C 		0.820 0.649
Nkx3-1
M09184_2.00 		Mus musculus
NYDAAGTGBYWD
HWRVCACTTHRN		 Misc
Kulakovskiy et al.(2013)
NKX31_MOUSE.H11MO.0.C 		0.820 0.649
NKX3-1
M09559_2.00 		Homo sapiens
BTRAGTRBYY
RRVYACTYAV		 Misc
Heinz et al.(2010)
LNCaP-Nkx3.1_GSE28264 		0.820 0.649
NKX3-1
M10729_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
P$GT1_Q6_01 		0.820 0.649
NKX3-1
M10730_2.00 		Homo sapiens
NWWTAAGTATWH
DWATACTTAWWN		 Transfac
Matys et al.(2006)
V$NKX3A_01 		0.820 0.649
NKX3-1
M10731_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NKX3A_Q3 		0.820 0.649
NKX3-1
M05256_2.00 		Homo sapiens
NNTAAGTGBN
NVCACTTANN		 SELEX
Yin et al.(2017)
NKX3-1_eDBD_Methyl-HT-SELEX_1 		0.820 0.649
NKX3-1
M05257_2.00 		Homo sapiens
NTAAYSWB
VWSRTTAN		 SELEX
Yin et al.(2017)
NKX3-1_eDBD_Methyl-HT-SELEX_2 		0.820 0.649
For this family, TFs with SR scores > 0.599 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M02076_2.00 Homeodomain 1 57

DNA Binding Domains

Protein ID Domain From To Sequence
ENSCINP00000015189 Homeodomain 156 212

Links

Other Homeodomain family TFs
Other Ciona intestinalis TFs

223 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
tetur04g08350 Tetranychus urticae tetur04g08350 I 0.849
PHUM439840 Pediculus humanus PHUM439840 I 0.841
NEMVEDRAFT_v1g208034 Nematostella vectensis NEMVEDRAFT_v1g208034 I 0.841
nkx3.3 Gasterosteus aculeatus ENSGACG00000007573 I 0.837
estExt_fgenesh2_pg.C_1430013 Branchiostoma floridae estExt_fgenesh2_pg.C_1430013 I 0.836
ENSLOCG00000009031 Lepisosteus oculatus ENSLOCG00000009031 I 0.836
nkx3-3 Xenopus tropicalis XB-GENE-479908 I 0.836
ENSLACG00000012763 Latimeria chalumnae ENSLACG00000012763 I 0.836
ENSORLG00000007716 Oryzias latipes ENSORLG00000007716 I 0.836
ISCW014989 Ixodes scapularis ISCW014989 I 0.836
ENSXMAG00000020095 Xiphophorus maculatus ENSXMAG00000020095 I 0.836
ENSPFOG00000020885 Poecilia formosa ENSPFOG00000020885 I 0.836
SMAR005030 Strigamia maritima SMAR005030 I 0.836
nkx3.3 Danio rerio ENSDARG00000069327 I 0.836
SPU_013047 Strongylocentrotus purpuratus SPU_013047 I 0.836
Sakowv30040088m.g Saccoglossus kowalevskii Sakowv30040088m.g I 0.836
ENSAMXG00000002250 Astyanax mexicanus ENSAMXG00000002250 I 0.836
CGI_10023919 Crassostrea gigas CGI_10023919 I 0.836
BGIBMGA010706 Bombyx mori BGIBMGA010706 I 0.829
MDOA010758 Musca domestica MDOA010758 I 0.829
AGAP003671 Anopheles gambiae AGAP003671 I 0.829
ADAC003526 Anopheles darlingi ADAC003526 I 0.829
RPRC001122 Rhodnius prolixus RPRC001122 I 0.829
SINV22315 Solenopsis invicta SINV22315 I 0.829
PPAI010327 Phlebotomus papatasi PPAI010327 I 0.829
AQUA001538 Anopheles quadriannulatus AQUA001538 I 0.829
LCUP000733 Lucilia cuprina LCUP000733 I 0.829
ASTEI07437 Anopheles stephensi ASTEI07437 I 0.829
GA20672 Drosophila pseudoobscura FBgn0080666 I 0.829
CLEC002956 Cimex lectularius CLEC002956 I 0.829
bap Drosophila sechellia FBgn0067536 I 0.829
NV25828 Nasonia vitripennis NV25828 I 0.829
GF18600 Drosophila ananassae FBgn0095618 I 0.829
Hsal_06436--XP_001120208.1_APIME Harpegnathos saltator Hsal_06436--XP_001120208.1_APIME I 0.829
ACYPI002893 Acyrthosiphon pisum ACYPI002893 I 0.829
GJ14311 Drosophila virilis FBgn0201526 I 0.829
GK14503 Drosophila willistoni FBgn0216509 I 0.829
GE25732 Drosophila yakuba FBgn0242790 I 0.829
GL27337 Drosophila persimilis FBgn0164918 I 0.829
GI21951 Drosophila mojavensis FBgn0144680 I 0.829
GG24598 Drosophila erecta FBgn0116730 I 0.829
GH22032 Drosophila grimshawi FBgn0129493 I 0.829
GB47401 Apis mellifera GB47401 I 0.829
CpipJ_CPIJ004109 Culex pipiens CpipJ_CPIJ004109 I 0.829
MCINX004875 Melitaea cinxia MCINX004875 I 0.829
MESCA006298 Megaselia scalaris MESCA006298 I 0.829
ACEP23863 Atta cephalotes ACEP23863 I 0.829
KGM_11246 Danaus plexippus KGM_11246 I 0.829
AAEL006597 Aedes aegypti AAEL006597 I 0.829
HelroG148616 Helobdella robusta HelroG148616 I 0.829
HMEL006181 Heliconius melpomene HMEL006181 I 0.829
ASIS007650 Anopheles sinensis ASIS007650 I 0.829
CPIJ004109 Culex quinquefasciatus CPIJ004109 I 0.829
ACUA019412 Anopheles culicifacies ACUA019412 I 0.829
ADIR005347 Anopheles dirus ADIR005347 I 0.829
ACOM028774 Anopheles coluzzii ACOM028774 I 0.829
ACHR006588 Anopheles christyi ACHR006588 I 0.829
AATE016309 Anopheles atroparvus AATE016309 I 0.829
AEPI001627 Anopheles epiroticus AEPI001627 I 0.829
AFAF013479 Anopheles farauti AFAF013479 I 0.829
AMEM005009 Anopheles merus AMEM005009 I 0.829
AMIN004031 Anopheles minimus AMIN004031 I 0.829
AMEC017317 Anopheles melas AMEC017317 I 0.829
AMAM011860 Anopheles maculatus AMAM011860 I 0.829
AFUN008966 Anopheles funestus AFUN008966 I 0.829
bap Drosophila simulans FBgn0067504 I 0.829
AARA010121 Anopheles arabiensis AARA010121 I 0.829
bap Drosophila melanogaster FBgn0004862 D 0.829
nkx3-1 Danio rerio ENSDARG00000078280 I 0.827
YQE_10102 Dendroctonus ponderosae YQE_10102 I 0.826
LDEC009723 Leptinotarsa decemlineata LDEC009723 I 0.826
TC012743 Tribolium castaneum TC012743 I 0.826
NKX3-2 Gorilla gorilla ENSGGOG00000008589 I 0.825
Nkx3-2 Rattus norvegicus ENSRNOG00000060782 I 0.825
NKX3-2 Callithrix jacchus ENSCJAG00000012159 I 0.825
NKX3-2 Cavia porcellus ENSCPOG00000005449 I 0.825
NKX3-2 Pteropus vampyrus ENSPVAG00000002830 I 0.825
ENSCSAG00000016338 Chlorocebus sabaeus ENSCSAG00000016338 I 0.825
ENSPPYG00000014611 Pongo abelii ENSPPYG00000014611 I 0.825
ENSPSIG00000012169 Pelodiscus sinensis ENSPSIG00000012169 I 0.825
NKX3-2 Myotis lucifugus ENSMLUG00000008362 I 0.825
ENSPTRG00000031253 Pan troglodytes ENSPTRG00000031253 I 0.825
nkx3.2 Gasterosteus aculeatus ENSGACG00000016378 I 0.825
ENSMICG00000000190 Microcebus murinus ENSMICG00000000190 I 0.825
ENSSSCG00000024594 Sus scrofa ENSSSCG00000024594 I 0.825
nkx3.2 Takifugu rubripes ENSTRUG00000014438 I 0.825
ENSTTRG00000003623 Tursiops truncatus ENSTTRG00000003623 I 0.825
ENSAMEG00000009342 Ailuropoda melanoleuca ENSAMEG00000009342 I 0.825
ENSGMOG00000018725 Gadus morhua ENSGMOG00000018725 I 0.825
NKX3-2 Loxodonta africana ENSLAFG00000031404 I 0.825
NKX3-2 Bos taurus ENSBTAG00000010896 I 0.825
ENSSTOG00000021803 Ictidomys tridecemlineatus ENSSTOG00000021803 I 0.825
ENSLOCG00000009892 Lepisosteus oculatus ENSLOCG00000009892 I 0.825
NKX3-2 Canis familiaris ENSCAFG00000015412 I 0.825
ENSMPUG00000000476 Mustela putorius furo ENSMPUG00000000476 I 0.825
nkx3.2 Danio rerio ENSDARG00000037639 I 0.825
ENSAMXG00000003840 Astyanax mexicanus ENSAMXG00000003840 I 0.825
Alligator_sinensis_CCG000534.1 Alligator sinensis Alligator_sinensis_CCG000534.1 I 0.825
NKX3-2 Oryctolagus cuniculus ENSOCUG00000009039 I 0.825
NKX3-2 Otolemur garnettii ENSOGAG00000015615 I 0.825
ENSONIG00000002379 Oreochromis niloticus ENSONIG00000002379 I 0.825
ENSEEUG00000012691 Erinaceus europaeus ENSEEUG00000012691 I 0.825
ENSXMAG00000016282 Xiphophorus maculatus ENSXMAG00000016282 I 0.825
nkx3-2.S Xenopus laevis XB-GENE-876836 I 0.825
Pvit_15821 Pogona vitticeps Pvit_15821 I 0.825
Nkx3-2 Mus musculus ENSMUSG00000049691 D 0.825
NKX3-2 Homo sapiens ENSG00000109705 D 0.825
ENSNLEG00000016256 Nomascus leucogenys ENSNLEG00000016256 I 0.825
nkx3-2 Xenopus tropicalis XB-GENE-876834 I 0.825
Ocbimv22026957m.g Octopus bimaculoides Ocbimv22026957m.g I 0.825
NKX3-2 Procavia capensis ENSPCAG00000013077 I 0.825
NKX3-2 Dasypus novemcinctus ENSDNOG00000043074 I 0.825
ENSPFOG00000002882 Poecilia formosa ENSPFOG00000002882 I 0.825
NKX3-2 Monodelphis domestica ENSMODG00000024753 I 0.825
ENSOPRG00000005452 Ochotona princeps ENSOPRG00000005452 I 0.825
ENSPANG00000021310 Papio anubis ENSPANG00000021310 I 0.825
nkx3-3.S Xenopus laevis XB-GENE-865322 I 0.825
ENSLACG00000003608 Latimeria chalumnae ENSLACG00000003608 I 0.825
nkx3.2 Oryzias latipes ENSORLG00000000593 I 0.825
ENSMMUG00000022026 Macaca mulatta ENSMMUG00000022026 I 0.825
LotgiG60615 Lottia gigantea LotgiG60615 I 0.823
ENSAPLG00000014690 Anas platyrhynchos ENSAPLG00000014690 I 0.822
ENSFALG00000011121 Ficedula albicollis ENSFALG00000011121 I 0.822
Myotis_brandtii_NKX3_10014306 Myotis brandtii Myotis_brandtii_NKX3_10014306 I 0.820
XP_002932598 Xenopus tropicalis XP_002932598 I 0.820
nkx3-1.S Xenopus laevis XB-GENE-6252708 I 0.820
nkx3-1.L Xenopus laevis XB-GENE-479031 I 0.820
ENSP00000370253 Macaca fascicularis ENSP00000370253 I 0.820
ENSBTAP00000001615-D1 Bos grunniens ENSBTAP00000001615-D1 I 0.820
ENSSSCG00000028216 Sus scrofa ENSSSCG00000028216 I 0.820
NKX3-1 Microcebus murinus ENSMICG00000011189 I 0.820
NKX3-1 Myotis lucifugus ENSMLUG00000006118 I 0.820
ENSLOCG00000015015 Lepisosteus oculatus ENSLOCG00000015015 I 0.820
NKX3-1 Loxodonta africana ENSLAFG00000008941 I 0.820
NKX3-1 Gorilla gorilla ENSGGOG00000014369 I 0.820
ENSXMAG00000020262 Xiphophorus maculatus ENSXMAG00000020262 I 0.820
NKX3-1 Macaca mulatta ENSMMUG00000009796 I 0.820
NKX3-1 Monodelphis domestica ENSMODG00000016789 I 0.820
ENSOARG00000010071 Ovis aries ENSOARG00000010071 I 0.820
NKX3-1 Oryctolagus cuniculus ENSOCUG00000004294 I 0.820
NKX3-1 Ornithorhynchus anatinus ENSOANG00000008027 I 0.820
ENSNLEG00000015968 Nomascus leucogenys ENSNLEG00000015968 I 0.820
ENSMPUG00000003418 Mustela putorius furo ENSMPUG00000003418 I 0.820
Nkx3-1 Mus musculus ENSMUSG00000022061 D 0.820
nkx3-1 Gasterosteus aculeatus ENSGACG00000010776 I 0.820
NKX3-1 Homo sapiens ENSG00000167034 D 0.820
ENSCAFG00000009107 Canis familiaris ENSCAFG00000009107 I 0.820
ENSCHOG00000011132 Choloepus hoffmanni ENSCHOG00000011132 I 0.820
NKX3-1 Bos taurus ENSBTAG00000001221 I 0.820
ENSAMXG00000024837 Astyanax mexicanus ENSAMXG00000024837 I 0.820
ENSACAG00000026683 Anolis carolinensis ENSACAG00000026683 I 0.820
ENSAMEG00000002866 Ailuropoda melanoleuca ENSAMEG00000002866 I 0.820
NKX3-1 Callithrix jacchus ENSCJAG00000020092 I 0.820
ENSCPOG00000010557 Cavia porcellus ENSCPOG00000010557 I 0.820
NKX3-1 Erinaceus europaeus ENSEEUG00000001113 I 0.820
NKX3-1 Echinops telfairi ENSETEG00000018790 I 0.820
ENSECAG00000001509 Equus caballus ENSECAG00000001509 I 0.820
NKX3-1 Dasypus novemcinctus ENSDNOG00000044451 I 0.820
ENSCSAG00000016229 Chlorocebus sabaeus ENSCSAG00000016229 I 0.820
NKX3-1 Otolemur garnettii ENSOGAG00000001303 I 0.820
ENSGMOG00000005518 Gadus morhua ENSGMOG00000005518 I 0.820
ENSPFOG00000009654 Poecilia formosa ENSPFOG00000009654 I 0.820
ENSSHAG00000015475 Sarcophilus harrisii ENSSHAG00000015475 I 0.820
ENSPCAG00000016644 Procavia capensis ENSPCAG00000016644 I 0.820
ENSPPYG00000018442 Pongo abelii ENSPPYG00000018442 I 0.820
ENSPSIG00000017342 Pelodiscus sinensis ENSPSIG00000017342 I 0.820
Nkx3-1 Rattus norvegicus ENSRNOG00000015477 I 0.820
NKX3-1 Pteropus vampyrus ENSPVAG00000005378 I 0.820
NKX3-1 Pan troglodytes ENSPTRG00000020081 I 0.820
ENSSARG00000001895 Sorex araneus ENSSARG00000001895 I 0.820
ENSPANG00000004934 Papio anubis ENSPANG00000004934 I 0.820
ENSONIG00000011762 Oreochromis niloticus ENSONIG00000011762 I 0.820
ENSTBEG00000002319 Tupaia belangeri ENSTBEG00000002319 I 0.820
nkx3-1 Oryzias latipes ENSORLG00000010925 I 0.820
NKX3-1 Vicugna pacos ENSVPAG00000004503 I 0.820
ENSTSYG00000007109 Tarsius syrichta ENSTSYG00000007109 I 0.820
NKX3-1 Ochotona princeps ENSOPRG00000003179 I 0.820
nkx3.2 Tetraodon nigroviridis ENSTNIG00000015732 I 0.815
SMU15003549 Schmidtea mediterranea SMU15003549 I 0.815
CapteG79432 Capitella teleta CapteG79432 I 0.815
ENSP00000371875 Macaca fascicularis ENSP00000371875 I 0.808
PXEA_0003190801 Protopolystoma xenopodis PXEA_0003190801 I 0.805
A_02450 Schistosoma haematobium A_02450 I 0.801
SMRZ_0000016501 Schistosoma margrebowiei SMRZ_0000016501 I 0.801
SMTD_0000549701 Schistosoma mattheei SMTD_0000549701 I 0.801
csin109461 Clonorchis sinensis csin109461 I 0.801
Smp_140730 Schistosoma mansoni Smp_140730 I 0.801
BGLB010692 Biomphalaria glabrata BGLB010692 I 0.789
TCLT_0000478201 Thelazia callipaeda TCLT_0000478201 I 0.733
Aan_R009530 Calypte anna Aan_R009530 I 0.713
ENSONIG00000018347 Oreochromis niloticus ENSONIG00000018347 I 0.698
D915_02578 Fasciola hepatica D915_02578 I 0.688
ENSTTRG00000012332 Tursiops truncatus ENSTTRG00000012332 I 0.681
MCOS_0000074801 Mesocestoides corti MCOS_0000074801 I 0.681
HelroG138724 Helobdella robusta HelroG138724 I 0.668
TTAC_0000184701 Hydatigera taeniaeformis TTAC_0000184701 I 0.645
ECANG7_00763 Echinococcus canadensis ECANG7_00763 I 0.645
TsM_000540100 Taenia solium TsM_000540100 I 0.645
EmuJ_000895600 Echinococcus multilocularis EmuJ_000895600 I 0.645
TASK_0000475201 Taenia asiatica TASK_0000475201 I 0.645
ENSAMXG00000009415 Astyanax mexicanus ENSAMXG00000009415 I 0.635
TTRE_0000463801 Trichuris trichiura TTRE_0000463801 I 0.632
D918_06873 Trichuris suis D918_06873 I 0.632
L893_g18140 Steinernema glaseri L893_g18140 I 0.629
BTMF_0000772101 Brugia timori BTMF_0000772101 I 0.624
nLs.2.1.2.g07743 Litomosoides sigmodontis nLs.2.1.2.g07743 I 0.624
NKX2-6 Canis familiaris ENSCAFG00000024691 I 0.617
ASIM_0001224701 Anisakis simplex ASIM_0001224701 I 0.617
NKX2-6 Equus caballus ENSECAG00000013714 I 0.617
NKX2-6 Pteropus vampyrus ENSPVAG00000005380 I 0.617
ENSTGUG00000004550 Taeniopygia guttata ENSTGUG00000004550 I 0.614
Minc11316 Meloidogyne incognita Minc11316 I 0.613
hlx Ciona intestinalis ENSCING00000019191 I 0.606
A_06201 Schistosoma haematobium A_06201 I 0.606
ENSPFOG00000009440 Poecilia formosa ENSPFOG00000009440 I 0.604
ENSONIG00000000279 Oreochromis niloticus ENSONIG00000000279 I 0.604
NKX2-3 Takifugu rubripes ENSTRUG00000002729 I 0.604
D917_04750 Trichinella nativa D917_04750 I 0.604
NKX2-3 Takifugu rubripes ENSTRUG00000003800 I 0.604
ENSXMAG00000005680 Xiphophorus maculatus ENSXMAG00000005680 I 0.604
ENSAMXG00000015414 Astyanax mexicanus ENSAMXG00000015414 I 0.603
tetur22g00030 Tetranychus urticae tetur22g00030 I 0.603
WUBG_10043 Wuchereria bancrofti WUBG_10043 I 0.601