|
HHAL007363-PA
(Halyomorpha halys)
Homeodomain
|
TF Information |
Pfam ID |
Interpro ID |
Gene ID |
CIS-BP ID |
Sequence source |
PF00046 (Homeobox) |
IPR001356 |
HHAL007363-PA |
T229851_2.00 |
Misc (2018-Jan-19) |
NCBI Gene Info:This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016] |
Directly determined binding motifs |
Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR Score |
DBD Identity |
No direct experiments |
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Motifs from related TFs |
Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR Score |
DBD Identity |
MEIS3
M03093_2.00 |
Homo sapiens |
![](data/2.00/DataFiles/Logos/Files/M03093_2.00_fwd.png) DTGACANN |
![](data/2.00/DataFiles/Logos/Files/M03093_2.00_rev.png) NNTGTCAH |
SELEX
Jolma et al.(2013)
MEIS3_1
|
0.815
|
0.667
|
MEIS3
M03094_2.00 |
Homo sapiens |
![](data/2.00/DataFiles/Logos/Files/M03094_2.00_fwd.png) TGACAGSTGTCA |
![](data/2.00/DataFiles/Logos/Files/M03094_2.00_rev.png) TGACASCTGTCA |
SELEX
Jolma et al.(2013)
MEIS3_2
|
0.815
|
0.667
|
MEIS3
M04951_2.00 |
Homo sapiens |
![](data/2.00/DataFiles/Logos/Files/M04951_2.00_fwd.png) TGWCABVTGWCA |
![](data/2.00/DataFiles/Logos/Files/M04951_2.00_rev.png) TGWCABVTGWCA |
SELEX
Yin et al.(2017)
MEIS3_eDBD_HT-SELEX
|
0.815
|
0.667
|
MEIS3
M04952_2.00 |
Homo sapiens |
![](data/2.00/DataFiles/Logos/Files/M04952_2.00_fwd.png) YGWCABVTGWCR |
![](data/2.00/DataFiles/Logos/Files/M04952_2.00_rev.png) YGWCABVTGWCR |
SELEX
Yin et al.(2017)
MEIS3_eDBD_Methyl-HT-SELEX
|
0.815
|
0.667
|
Q5EVH4_OIKDI
M02227_2.00 |
Oikopleura dioica |
![](data/2.00/DataFiles/Logos/Files/M02227_2.00_fwd.png) NTGACAKN |
![](data/2.00/DataFiles/Logos/Files/M02227_2.00_rev.png) NMTGTCAN |
PBM
Weirauch et al.(2014)
pTH6041
|
0.792
|
0.769
|
KNAT7
M01064_2.00 |
Arabidopsis thaliana |
![](data/2.00/DataFiles/Logos/Files/M01064_2.00_fwd.png) TGACRKST |
![](data/2.00/DataFiles/Logos/Files/M01064_2.00_rev.png) ASMYGTCA |
PBM
Sullivan et al.(2014)
pTH9798
|
0.673
|
0.487
|
KNAT4
M01238_2.00 |
Arabidopsis thaliana |
![](data/2.00/DataFiles/Logos/Files/M01238_2.00_fwd.png) NNGACNNNN |
![](data/2.00/DataFiles/Logos/Files/M01238_2.00_rev.png) NNNNGTCNN |
PBM
Lambert et al.(2019)
pTH9968
|
0.669
|
0.487
|
KNAT3
M02051_2.00 |
Arabidopsis thaliana |
![](data/2.00/DataFiles/Logos/Files/M02051_2.00_fwd.png) NNNGACVBNN |
![](data/2.00/DataFiles/Logos/Files/M02051_2.00_rev.png) NNVBGTCNNN |
PBM
Weirauch et al.(2014)
pTH7600
|
0.669
|
0.462
|
HOS66
M02156_2.00 |
Oryza sativa |
![](data/2.00/DataFiles/Logos/Files/M02156_2.00_fwd.png) NNNNDHNN |
![](data/2.00/DataFiles/Logos/Files/M02156_2.00_rev.png) NNDHNNNN |
PBM
Weirauch et al.(2014)
pTH8332
|
0.634
|
0.487
|
For this family, TFs with SR scores > 0.599 will likely have a similar motif |